Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q16637 (SMA)
 8,107 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nitrogen balance measurements were carried out on children aged 5 to 30 months. They were fed diets supplemented by PRFMs or by SMA milk powder as the sole source of dietary protein. Sesamena (or SLW-II) was fed to a group of 8 children, Arabeana to another group of 9 and Supramine to a third group of 8 children. The measurements were reported on the same children when they were given SMA milk powder as a reference protein. Therefore, each subject acted as his own control. The technique used was that of Fomon et al(23) with certain modifications. All three mixtures could maintain the children in positive nitrogen balance. Sesamena gave the best mean NPU value (69 +/- 5.9) which is 96% of reference. Supramine gave the highest mean digestibility (87 +/- 6.8) which is 102% of reference. Sesamena proved to be a suitable weaning food satisfying all the standards of PRFMs recommended by the PAG(14,15). It contains a good quality protein, cheap and can be easily prepared at the family level after appropriate education of mothers. This mixture can be also manufactured at the national level.
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PMID:Nitrogen balance studies on protein-rich food mixtures for preschool children in Egypt. 122 94

Studying of the impact of social context on the perception of pain in others is important for understanding the role of intentionality in interpersonal sensitivity, empathy, and implicit moral reasoning. Here we used an event-related fMRI with pain and social context (i.e., the number of individuals in the stimuli) as the two factors to investigate how different social contexts and resulting perceived agency modulate the neural response to the perception of pain in others. Twenty-six healthy participants were scanned while presented with short dynamic visual stimuli depicting painful situations accidentally caused by or intentionally caused by another individual. The main effect of perception of pain was associated with signal increase in the aMCC, insula, somatosensory cortex, SMA and PAG. Importantly, perceiving the presence of another individual led to specific hemodynamic increase in regions involved in representing social interaction and emotion regulation including the temporoparietal junction, medial prefrontal cortex, inferior frontal gyrus, and orbitofrontal cortex. Furthermore, the functional connectivity pattern between the left amygdala and other brain areas was modulated by the perceived agency. Our study demonstrates that the social context in which pain occurs modulate the brain response to other's pain. This modulation may reflect successful adaptation to potential danger present in a social interaction. Our results contribute to a better understanding of the neural mechanisms underpinning implicit moral reasoning that concern actions that can harm other people.
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PMID:Social context and perceived agency affects empathy for pain: an event-related fMRI investigation. 1943 83