Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UNIPROT:Q14790 (caspase-8)
8,899 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein caspase-8 8899 caspase-3 3908 caspase-9 2457 Fas 1925 Bcl-2 1847 cytochrome c 1489 Bid 959 p53 844 tumor necrosis factor 794 Mol 768 PARP 725 FADD 697 Sep 614 TNF 569 TRAIL 520 CD95 492 Fas ligand 444 FasL 444 FLICE 393 cytokine 381 annexin V 373 p38 361 DR5 340 c-FLIP 339 JNK 334 FLIP 327 poly(ADP-ribose) polymerase 295 endoplasmic reticulum 261 p21 255 MAPK 222 Bak 218 DR4 216 Tumor necrosis factor 215 XIAP 215 ROS 209 RIPK1 206 ERK 197 TNF-alpha 193 cytochrome 183 TNF receptor 180 Smac 170 inhibitor of apoptosis 167 TNF-related apoptosis-inducing ligand 166 GSH 165 Mcl-1 159 poly (ADP-ribose) polymerase 158 CD95L 156 survivin 154 BID 152 c-Jun 152 proteasome 151 AKT 147 PI3K 144 RIPK3 142 TRAIL-R1 136 p65 132 Apaf-1 131 ERK1 129 interacting protein 126 catalase 123 RIP1 121 TRAIL-R2 119 Bcl-X 118 DIABLO 116 TNFR1 115 anti-apoptotic protein 115 APO-1 115 superoxide dismutase 114 cyclin D1 114 ATP 114 FAS 111 bcl-2 111 MLKL 110 lipopolysaccharide 108 ubiquitin 106 BAX 106 IFN 106 IL-6 106 death receptor 5 104 Fas-associated death domain protein 103 more...

Disease cancer 2331 tumor 1381 leukemia 441 breast cancer 381 hepatocellular carcinoma 289 tumor growth 271 carcinoma 264 MCF 262 colon cancer 214 prostate cancer 190 lung cancer 167 GSH 165 neuroblastoma 158 melanoma 157 lymphoma 154 ischemia 153 adenocarcinoma 149 glioma 146 carcinogenesis 139 colorectal cancer 131 multiple myeloma 125 B-cell lymphoma 113 tumorigenesis 111 FAS 111 glioblastoma 90 gastric cancer 90 acute myeloid leukemia 89 diabetes 89 squamous cell carcinoma 89 cervical cancer 82 ovarian cancer 81 Alzheimer's disease 77 liver cancer 77 virus infection 76 osteosarcoma 74 non-small cell lung cancer 74 tumor progression 73 acute promyelocytic leukemia 70 HIV 60 pancreatic cancer 58 liver cancer 54 lung carcinoma 53 sepsis 51 sepsis 49 infectious diseases 49 Blocking 47 stroke 45 epithelial ovarian cancer 45 acute lymphoblastic leukemia 44 herpes simplex 41 immunodeficiency 39 bladder cancer 38 CEM 38 skin cancer 38 Parkinson's disease 37 Leukemia 37 renal cell carcinoma 36 chronic myeloid leukemia 36 metastases 36 Infection 35 atherosclerosis 35 AGS 32 heart failure 32 Tumour necrosis 32 chronic lymphocytic leukemia 31 DDP 31 myeloid leukemia 30 brain tumor 30 oral cancer 30 glioblastoma multiforme 29 autoimmune disease 29 obesity 28 rheumatoid arthritis 28 retinoblastoma 28 solid tumor 27 cytomegalovirus 27 ATM 27 cerebral ischemia 27 SCID 26 inflammatory bowel disease 26 more...

Symptom collapse 51 starvation 21 seizures 15 hypothermia 12 diarrhea 12 hyperoxia 11 splenomegaly 10 pain 9 functional recovery 8 anesthesia 5 weakness 5 exhaustion 5 cachexia 4 respiratory distress 4 thinning 4 insomnia 3 memory loss 3 skin damage 3 dry eye 3 headache 3 nausea 2 sore throat 2 tremor 2 back pain 2 dyspnea 2 overweight 2 abdominal pain 2 myalgia 1 bradypnea 1 angina 1 hypotonia 1 discomfort 1 discomfort 1 loss of equilibrium 1 Tenderness 1 tinnitus 1 nausea and vomiting 1 loss of balance 1 ataxia 1 menopausal symptoms 1 HSA 1 hepatomegaly 1 hot flashes 1 dizziness 1 acute stress 1 sleepiness 1 acidity 1 ataxic gait 1 bone pain 1 dystonia 1 spasm 1 erythema 1 nasal discharge 1 low back pain 1 hyperemesis 1 halitosis 1 hepatosplenomegaly 1 syncope 1 vomiting 1

Drug ROS 209 IL-2 55 IFN-gamma 51 Dermatol 35 Bortezomib 34 lysine 30 p75 26 vitamin E 22 ascorbate 20 MAP 18 Taxol 18 CSF 17 Arsenic trioxide 17 Monit 15 IFN-beta 14 Cardiovasc 12 ADR 11 Glycyrrhiza 11 caffeine 10 Flavopiridol 9 Etoposide 9 Ethanol 9 Glutathione 8 MRC 8 Mutagen 8 CED 8 AMC 7 CTX 7 2-Methoxyestradiol 7 Sorafenib 7 CCL 6 G-CSF 6 Propofol 6 EE2 6 Indomethacin 6 ICI 6 DHT 6 DHT 6 -deoxyadenosine 6 Vorinostat 5 Simvastatin 5 Oxaliplatin 5 Vitamin E 5 Vitamin K 5 Docetaxel 5 Dasatinib 5 Ginseng 5 NVP 4 Adriamycin 4 Emodin 4 lactose 4 EPA 4 CoCl2 4 Epigallocatechin 4 PFT 4 TAT 4 Fraction 4 Emodin 4 ALA 4 Angiotensin II 4 uPA 4 NADH 4 CoCl2 4 CPT-11 4 ZnO 3 CA-074 3 Lenalidomide 3 TTC 3 Vitamin B 3 CTX 3 Vitamin A 3 CTX 3 ADM 3 Silica 3 Hyperforin 3 Amiloride 3 Radicicol 3 Trabectedin 3 Cantor 3 Phosphatidylserine 3 more...

Enzyme caspase-8 6750 caspase-3 3202 caspase-9 2021 mitogen-activated protein kinase 804 PARP 790 ERK 301 caspase-1 248 protein kinase 211 superoxide dismutase 169 caspase-2 158 caspase-2 157 catalase 151 proteasome 151 caspase-7 146 caspase-7 143 caspase-10 116 caspase-10 112 protein kinase C 107 caspase-6 100 caspase-6 96 MEK 94 focal adhesion kinase 87 lactate dehydrogenase 74 luciferase 71 cdc2 71 phosphatidylinositol 3-kinase 63 granzyme B 53 glutathione peroxidase 53 caspase-4 52 IKK 52 caspase-4 47 alanine aminotransferase 45 calcineurin 40 cathepsin B 38 TdT 36 aspartate aminotransferase 36 glutathione S-transferase 35 ATPase 34 P-glycoprotein 32 RNase 31 RNase 31 caspase-11 30 caspase-11 30 GSK 28 AMP-activated protein kinase 28 peroxidase 27 MMP 27 NADPH oxidase 27 NADPH oxidase 26 topoisomerase 25 topoisomerase 25 reverse transcriptase 25 phosphoinositide 3-kinase 23 succinate dehydrogenase 23 cathepsin D 22 glutathione reductase 21 complex I 20 RNA polymerase 19 NO synthase 19 Omi/HtrA2 18 alkaline phosphatase 17 AMPK 16 MAP 16 AMPK 15 protein phosphatase 2A 14 phospholipase C 14 trypsin 14 collagenase 13 neutral sphingomyelinase 13 NOS 13 CAD 12 CAD 12 CAD 12 DNA ligase 11 DNA ligase 11 ribonucleotide reductase 11 AST 11 ribonuclease 11 DNase 11 ribonucleotide reductase 11 more...

Compound DNA 1446 oxygen 831 Dec 692 TNF 569 MTT 373 cysteine 295 MDA 209 Asp 208 dUTP 183 GSH 170 GSH 170 iodine 164 calcium 155 alanine 137 Clin 136 ADP-ribose 131 glucose 128 ATP 114 nitric oxide 110 N-acetylcysteine 109 boron 105 bromide 103 serine 102 water 94 sodium 91 threonine 85 hydrogen 79 tyrosine 78 ADP 77 ADP 74 ADP 73 Curcumin 57 ethanol 54 acetate 52 THP 49 DDP 49 THP 49 MEK 49 acridine 49 Ile 48 Cytochrome c 44 H2O2 44 leucine 43 ADR 41 NH2 41 Cyt 41 ASC 40 Hoechst 33342 39 zinc 38 arginine 36 retinoic acid 36 ethyl acetate 36 phosphate 35 Adriamycin 35 glutamate 35 Panam 34 lysine 33 CAT 30 CAT 30 CAT 30 nitrogen 30 His 28 5-FU 27 cadmium 27 sulfate 27 galactose 27 aldehyde 25 selenium 25 aspartic acid 24 aspartic acid 24 Pac 24 iron 23 aldehyde 23 methanol 23 aspartic acid 23 urea 23 aspartic acid 23 copper 22 proline 22 glutamine 22 more...

---