Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q14790 (caspase-8)
 8,899 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CASP8 protein 11.8
ubiquitin specific protease 47 11.8
EFR3 homolog B 11.8
caspase-8 11.8
Death associated protein 3 11.8
H2BFM 11.8
TNFRSF6 protein 11.8
caspase and RIP adapter with death domain 11.8
Fas-associated death domain protein 10.9
FADD 10.9
caspase 10 10.8
VLIG-1 10.8
sorting nexin 7 10.8
G1/S-specific cyclin E2 10.8
C4orf22 10.8
Apoptotic peptidase activating factor 1 10.8
DEDD2 10.8
Sal-like 4 (Drosophila) 10.8
FLICE 10.7
c-FLIP 10.7
Bid 10.5
FAS-associated death domain protein 10.4
FLIP 10.2
APACD 10.2
EPH receptor B4 10.2
FLICE-associated huge protein 10.2
DOPEY1 10.2
inhibitor of growth family, member 3 10.2
RELL2 10.2
PTPRK protein 10.2
death effector domain-containing 10.0
DFF35 9.9
TNFR1-associated death domain protein 9.9
FADD protein 9.9
caspase-9 9.9
uveal autoantigen with coiled-coil domains and ankyrin repeats 9.8
EFR3B 9.8
PMEPA1 protein 9.8
BAP29 9.8
Squamous cell carcinoma antigen 1 9.8
more...
Disease
BRIC2 10.2
HMN7B 9.8
Acute glaucoma 9.1
Reovirus infection 8.6
Coliform mastitis 8.5
Chronic Chagas' disease 8.1
DFNB59 7.9
autoimmune lymphoproliferative syndrome 7.8
methionine synthase deficiency 7.8
Hypersensitivity syndrome 7.4
AIDS cholangiopathy 7.4
CYLD 7.2
Corneal infection 6.9
amok 6.7
FAS 6.6
Geographic atrophy 6.6
AD5 6.6
KRS 6.6
salivary gland adenoid cystic carcinoma 6.6
salivary gland cancer 6.5
Polypoidal choroidal vasculopathy 6.5
Epidermolysis bullosa simplex 6.3
recurrent osteosarcoma 6.3
Parasitic infection 6.3
Extranodal NK/T-cell lymphoma, nasal type 6.3
childhood rhabdomyosarcoma 6.2
mouse leukemia P388 6.2
VED 6.2
salivary gland adenocarcinoma 6.0
Testicular Cancer 5.9
colon neoplasm 5.9
Cytokine storm 5.9
Tumour necrosis 5.9
DFNA5 5.9
cowpox 5.8
Polycystic liver disease 5.7
Epithelioma 5.7
Chronic beryllium disease 5.7
molluscum contagiosum 5.7
AGS 5.7
more...
Symptom
loss of equilibrium 4.7
bradypnea 4.2
hyperemesis 3.6
Tenderness 3.3
loss of balance 3.0
hyperoxia 2.9
skin damage 2.8
ataxic gait 2.7
collapse 2.7
halitosis 2.6
dry eye 2.0
splenomegaly 1.9
hot flashes 1.7
starvation 1.6
memory loss 1.6
nasal discharge 1.4
sore throat 1.4
cachexia 1.3
hypothermia 1.3
menopausal symptoms 1.1
functional recovery 1.1
exhaustion 0.4
thinning 0.3
HSA 0.3
bone pain 0.2
insomnia 0.0
hepatosplenomegaly -0.3
acute stress -0.4
diarrhea -0.4
respiratory distress -0.5
seizures -0.6
hepatomegaly -0.7
hypotonia -0.7
back pain -0.8
myalgia -0.9
tinnitus -0.9
spasm -1.0
weakness -1.1
dystonia -1.2
tremor -1.4
more...
Drug
Edratide 11.8
2-Iminobiotin 9.2
Lexatumumab 9.2
Alexidine 8.8
Zedoary 8.5
Mapatumumab 8.5
Methadone hydrochloride 8.3
Bear bile 8.3
Cupric sulfate 7.8
Citrus unshiu peel 7.7
Naftopidil 7.5
Mevastatin 7.4
Radicicol 7.3
Flavopiridol 7.3
Epothilone B 7.3
2-Methoxyestradiol 7.2
Avasimibe 7.2
Motexafin gadolinium 7.1
Berberine chloride 7.1
Sodium ascorbate 7.1
Irofulven 6.9
Revlimid 6.7
Lonafarnib 6.6
CA-074 6.6
Ilomastat 6.6
Bucillamine 6.5
Bortezomib 6.3
Peridinin 6.3
Olomoucine 6.3
Hyperforin 6.3
Trabectedin 6.2
Nafamostat mesilate 5.8
Dextran sulfate sodium 5.8
Zebularine 5.7
Tipifarnib 5.7
Vorinostat 5.7
Cilengitide 5.6
CED 5.6
Arsenic trioxide 5.6
Alimta 5.5
more...
Enzyme
caspase-8 11.8
caspase-10 11.1
caspase-10 11.1
caspase-9 9.9
caspase-2 9.5
caspase-6 9.5
caspase-6 9.5
caspase-2 9.4
caspase-7 9.2
caspase-7 9.1
caspase-4 8.9
caspase-4 8.8
caspase-3 8.3
caspase-11 8.3
caspase-11 8.3
caspase-5 8.2
caspase-5 8.1
PARP 7.7
lombricine kinase 7.6
Omi/HtrA2 7.6
caspase-1 7.1
AO1 6.6
adamalysin 6.5
neutral sphingomyelinase 6.1
TdT 6.1
granzyme B 5.8
DIPP 5.8
deoxyhypusine hydroxylase 5.8
10-formyltetrahydrofolate dehydrogenase 5.7
3-hydroxy-3-methylglutaryl-CoA lyase 5.5
sphingomyelin synthase 5.5
lysyl-tRNA synthetase 5.3
IKK 5.2
mu-calpain 5.2
m-calpain 5.1
PTR1 5.1
ECH 5.1
aspartase 5.1
glutaryl-CoA dehydrogenase 5.1
cathepsin B 5.0
more...
Compound
estra-1,3,5(10)-trien-17-ol 11.8
Defenuron 10.8
4-chloro-N-methylbenzamide 10.8
Justicidin A 10.5
C14H21N3O2 10.2
C14H21N3O2 10.2
C14H21N3O2 10.2
Glucoraphenin 10.2
C14H21N3O2 10.2
C14H21N3O2 10.2
24-Hydroxycholesterol 10.2
Cephalochromin 10.2
Lupulone 10.0
Dihydrosanguinarine 9.8
C14H21N3O2 9.8
Sarcophine 9.8
Kinetin riboside 9.8
Codeinone 9.8
Cephalostatin 1 9.6
Decylubiquinone 9.5
Saucernetin 9.5
Tigogenin 9.5
C14H21N3O2 9.5
Valtrate 9.5
2-hexadecanol 9.5
C14H21N3O2 9.5
Kinetin riboside 9.5
C14H21N3O2 9.2
Gartanin 9.2
2,5-Dihydroxyacetophenone 9.2
alpha-Santalol 9.2
Raddeanin A 9.1
Linoelaidic acid 9.0
Deltonin 9.0
methyl 2-benzoylbenzoate 9.0
Sinularin 8.8
1-pyrrolidinecarbodithioic acid 8.8
androst-2-en-17-one 8.8
C14H21N3O2 8.8
Rocaglamide 8.7
more...