Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q14790 (
caspase-8
)
8,899
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase-8
8899
caspase-3
3908
caspase-9
2457
Fas
1925
Bcl-2
1847
cytochrome c
1489
Bid
959
p53
844
tumor necrosis factor
794
Mol
768
PARP
725
FADD
697
Sep
614
TNF
569
TRAIL
520
CD95
492
Fas ligand
444
FasL
444
FLICE
393
cytokine
381
annexin V
373
p38
361
DR5
340
c-FLIP
339
JNK
334
FLIP
327
poly(ADP-ribose) polymerase
295
endoplasmic reticulum
261
p21
255
MAPK
222
Bak
218
DR4
216
XIAP
215
Tumor necrosis factor
215
ROS
209
RIPK1
206
ERK
197
TNF-alpha
193
cytochrome
183
TNF receptor
180
more...
Disease
cancer
2331
tumor
1381
leukemia
441
breast cancer
381
hepatocellular carcinoma
289
tumor growth
271
carcinoma
264
MCF
262
colon cancer
214
prostate cancer
190
lung cancer
167
GSH
165
neuroblastoma
158
melanoma
157
lymphoma
154
ischemia
153
adenocarcinoma
149
glioma
146
carcinogenesis
139
colorectal cancer
131
multiple myeloma
125
B-cell lymphoma
113
FAS
111
tumorigenesis
111
gastric cancer
90
glioblastoma
90
acute myeloid leukemia
89
diabetes
89
squamous cell carcinoma
89
cervical cancer
82
ovarian cancer
81
liver cancer
77
Alzheimer's disease
77
virus infection
76
non-small cell lung cancer
74
osteosarcoma
74
tumor progression
73
acute promyelocytic leukemia
70
HIV
60
pancreatic cancer
58
more...
Symptom
collapse
51
starvation
21
seizures
15
hypothermia
12
diarrhea
12
hyperoxia
11
splenomegaly
10
pain
9
functional recovery
8
anesthesia
5
exhaustion
5
weakness
5
cachexia
4
respiratory distress
4
thinning
4
insomnia
3
memory loss
3
dry eye
3
skin damage
3
headache
3
nausea
2
tremor
2
overweight
2
dyspnea
2
back pain
2
sore throat
2
abdominal pain
2
myalgia
1
bradypnea
1
angina
1
hypotonia
1
discomfort
1
discomfort
1
loss of equilibrium
1
Tenderness
1
tinnitus
1
nausea and vomiting
1
ataxia
1
hepatomegaly
1
hot flashes
1
more...
Drug
ROS
209
IL-2
55
IFN-gamma
51
Dermatol
35
Bortezomib
34
lysine
30
p75
26
vitamin E
22
ascorbate
20
MAP
18
Taxol
18
Arsenic trioxide
17
CSF
17
Monit
15
IFN-beta
14
Cardiovasc
12
ADR
11
Glycyrrhiza
11
caffeine
10
Flavopiridol
9
Ethanol
9
Etoposide
9
Glutathione
8
CED
8
Mutagen
8
MRC
8
2-Methoxyestradiol
7
Sorafenib
7
CTX
7
AMC
7
-deoxyadenosine
6
DHT
6
Propofol
6
ICI
6
DHT
6
Indomethacin
6
G-CSF
6
CCL
6
EE2
6
Oxaliplatin
5
more...
Enzyme
caspase-8
6750
caspase-3
3202
caspase-9
2021
mitogen-activated protein kinase
804
PARP
790
ERK
301
caspase-1
248
protein kinase
211
superoxide dismutase
169
caspase-2
158
caspase-2
157
catalase
151
proteasome
151
caspase-7
146
caspase-7
143
caspase-10
116
caspase-10
112
protein kinase C
107
caspase-6
100
caspase-6
96
MEK
94
focal adhesion kinase
87
lactate dehydrogenase
74
luciferase
71
cdc2
71
phosphatidylinositol 3-kinase
63
granzyme B
53
glutathione peroxidase
53
caspase-4
52
IKK
52
caspase-4
47
alanine aminotransferase
45
calcineurin
40
cathepsin B
38
aspartate aminotransferase
36
TdT
36
glutathione S-transferase
35
ATPase
34
P-glycoprotein
32
RNase
31
more...
Compound
DNA
1446
oxygen
831
Dec
692
TNF
569
MTT
373
cysteine
295
MDA
209
Asp
208
dUTP
183
GSH
170
GSH
170
iodine
164
calcium
155
alanine
137
Clin
136
ADP-ribose
131
glucose
128
ATP
114
nitric oxide
110
N-acetylcysteine
109
boron
105
bromide
103
serine
102
water
94
sodium
91
threonine
85
hydrogen
79
tyrosine
78
ADP
77
ADP
74
ADP
73
Curcumin
57
ethanol
54
acetate
52
THP
49
MEK
49
DDP
49
THP
49
acridine
49
Ile
48
more...