Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q14790 (caspase-8)
8,899 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-8 8899
caspase-3 3908
caspase-9 2457
Fas 1925
Bcl-2 1847
cytochrome c 1489
Bid 959
p53 844
tumor necrosis factor 794
Mol 768
PARP 725
FADD 697
Sep 614
TNF 569
TRAIL 520
CD95 492
Fas ligand 444
FasL 444
FLICE 393
cytokine 381
annexin V 373
p38 361
DR5 340
c-FLIP 339
JNK 334
FLIP 327
poly(ADP-ribose) polymerase 295
endoplasmic reticulum 261
p21 255
MAPK 222
Bak 218
DR4 216
XIAP 215
Tumor necrosis factor 215
ROS 209
RIPK1 206
ERK 197
TNF-alpha 193
cytochrome 183
TNF receptor 180
more...
Disease
cancer 2331
tumor 1381
leukemia 441
breast cancer 381
hepatocellular carcinoma 289
tumor growth 271
carcinoma 264
MCF 262
colon cancer 214
prostate cancer 190
lung cancer 167
GSH 165
neuroblastoma 158
melanoma 157
lymphoma 154
ischemia 153
adenocarcinoma 149
glioma 146
carcinogenesis 139
colorectal cancer 131
multiple myeloma 125
B-cell lymphoma 113
FAS 111
tumorigenesis 111
gastric cancer 90
glioblastoma 90
acute myeloid leukemia 89
diabetes 89
squamous cell carcinoma 89
cervical cancer 82
ovarian cancer 81
liver cancer 77
Alzheimer's disease 77
virus infection 76
non-small cell lung cancer 74
osteosarcoma 74
tumor progression 73
acute promyelocytic leukemia 70
HIV 60
pancreatic cancer 58
more...
Symptom
collapse 51
starvation 21
seizures 15
hypothermia 12
diarrhea 12
hyperoxia 11
splenomegaly 10
pain 9
functional recovery 8
anesthesia 5
exhaustion 5
weakness 5
cachexia 4
respiratory distress 4
thinning 4
insomnia 3
memory loss 3
dry eye 3
skin damage 3
headache 3
nausea 2
tremor 2
overweight 2
dyspnea 2
back pain 2
sore throat 2
abdominal pain 2
myalgia 1
bradypnea 1
angina 1
hypotonia 1
discomfort 1
discomfort 1
loss of equilibrium 1
Tenderness 1
tinnitus 1
nausea and vomiting 1
ataxia 1
hepatomegaly 1
hot flashes 1
more...
Drug
ROS 209
IL-2 55
IFN-gamma 51
Dermatol 35
Bortezomib 34
lysine 30
p75 26
vitamin E 22
ascorbate 20
MAP 18
Taxol 18
Arsenic trioxide 17
CSF 17
Monit 15
IFN-beta 14
Cardiovasc 12
ADR 11
Glycyrrhiza 11
caffeine 10
Flavopiridol 9
Ethanol 9
Etoposide 9
Glutathione 8
CED 8
Mutagen 8
MRC 8
2-Methoxyestradiol 7
Sorafenib 7
CTX 7
AMC 7
-deoxyadenosine 6
DHT 6
Propofol 6
ICI 6
DHT 6
Indomethacin 6
G-CSF 6
CCL 6
EE2 6
Oxaliplatin 5
more...
Enzyme
caspase-8 6750
caspase-3 3202
caspase-9 2021
mitogen-activated protein kinase 804
PARP 790
ERK 301
caspase-1 248
protein kinase 211
superoxide dismutase 169
caspase-2 158
caspase-2 157
catalase 151
proteasome 151
caspase-7 146
caspase-7 143
caspase-10 116
caspase-10 112
protein kinase C 107
caspase-6 100
caspase-6 96
MEK 94
focal adhesion kinase 87
lactate dehydrogenase 74
luciferase 71
cdc2 71
phosphatidylinositol 3-kinase 63
granzyme B 53
glutathione peroxidase 53
caspase-4 52
IKK 52
caspase-4 47
alanine aminotransferase 45
calcineurin 40
cathepsin B 38
aspartate aminotransferase 36
TdT 36
glutathione S-transferase 35
ATPase 34
P-glycoprotein 32
RNase 31
more...
Compound
DNA 1446
oxygen 831
Dec 692
TNF 569
MTT 373
cysteine 295
MDA 209
Asp 208
dUTP 183
GSH 170
GSH 170
iodine 164
calcium 155
alanine 137
Clin 136
ADP-ribose 131
glucose 128
ATP 114
nitric oxide 110
N-acetylcysteine 109
boron 105
bromide 103
serine 102
water 94
sodium 91
threonine 85
hydrogen 79
tyrosine 78
ADP 77
ADP 74
ADP 73
Curcumin 57
ethanol 54
acetate 52
THP 49
MEK 49
DDP 49
THP 49
acridine 49
Ile 48
more...