Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q14790 (
caspase-8
)
8,899
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase-8
8899
caspase-3
3908
caspase-9
2457
Fas
1925
Bcl-2
1847
cytochrome c
1489
Bid
959
p53
844
tumor necrosis factor
794
Mol
768
PARP
725
FADD
697
Sep
614
TNF
569
TRAIL
520
CD95
492
Fas ligand
444
FasL
444
FLICE
393
cytokine
381
more...
Disease
cancer
2331
tumor
1381
leukemia
441
breast cancer
381
hepatocellular carcinoma
289
tumor growth
271
carcinoma
264
MCF
262
colon cancer
214
prostate cancer
190
lung cancer
167
GSH
165
neuroblastoma
158
melanoma
157
lymphoma
154
ischemia
153
adenocarcinoma
149
glioma
146
carcinogenesis
139
colorectal cancer
131
more...
Symptom
collapse
51
starvation
21
seizures
15
diarrhea
12
hypothermia
12
hyperoxia
11
splenomegaly
10
pain
9
functional recovery
8
exhaustion
5
anesthesia
5
weakness
5
respiratory distress
4
cachexia
4
thinning
4
memory loss
3
insomnia
3
dry eye
3
skin damage
3
headache
3
more...
Drug
ROS
209
IL-2
55
IFN-gamma
51
Dermatol
35
Bortezomib
34
lysine
30
p75
26
vitamin E
22
ascorbate
20
Taxol
18
MAP
18
CSF
17
Arsenic trioxide
17
Monit
15
IFN-beta
14
Cardiovasc
12
ADR
11
Glycyrrhiza
11
caffeine
10
Etoposide
9
more...
Enzyme
caspase-8
6750
caspase-3
3202
caspase-9
2021
mitogen-activated protein kinase
804
PARP
790
ERK
301
caspase-1
248
protein kinase
211
superoxide dismutase
169
caspase-2
158
caspase-2
157
catalase
151
proteasome
151
caspase-7
146
caspase-7
143
caspase-10
116
caspase-10
112
protein kinase C
107
caspase-6
100
caspase-6
96
more...
Compound
DNA
1446
oxygen
831
Dec
692
TNF
569
MTT
373
cysteine
295
MDA
209
Asp
208
dUTP
183
GSH
170
GSH
170
iodine
164
calcium
155
alanine
137
Clin
136
ADP-ribose
131
glucose
128
ATP
114
nitric oxide
110
N-acetylcysteine
109
more...