Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q07644 (polypeptide)
 72,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Matricin, a fundamental protein fibrillar structure of the eucaryotic cell nucleus, has been isolated from the rat liver nuclear matrix. The isolated matricin forms a diffuse reticulum of 30--50 A fibrils and consists predominantly of three primary polypeptide fractions with apparent molecular weights of 62,000, 66,000 and 70,000. Aside from a major role in nuclear structure, matricin may provide an important functional milieu for such fundamental nuclear processes as replication, transcription and the processing and transport of RNA.
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PMID:Matricin fibrils: isolation of the primary nuclear matrix polypeptides. 738 67