Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q06643 (
non-Hodgkin's lymphoma
)
11,307
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
AA-type amyloidosis is a consequence of a long-standing systemic inflammation and is not associated with a monoclonal protein or clonal bone marrow plasma cells. Proinflammatory cytokines such as interleukin (IL)1, IL-6, and tumor necrosis factor (TNF) stimulate the synthesis of
serum amyloid A
during inflammation. Although the association of
non-Hodgkin's lymphoma
(
NHL
) with AL-type amyloidosis is well known and patients with Hodgkin's lymphoma with AA amyloidosis have been described, AA-type amyloidosis with
NHL
is extremely infrequent. We report a case of amyloidosis associated with
NHL
that subsided during R-CHOP chemotherapy.
...
PMID:A patient with diffuse large B-cell non-Hodgkin's lymphoma and AA type amyloidosis. 1840 97
Amyloidosis in
non-Hodgkin's lymphoma
(
NHL
) is known to be of the AL type, and AA-type amyloidosis in
NHL
is extremely rare. Herein is reported an autopsy case of follicular lymphoma that transformed to diffuse large B-cell lymphoma (DLBCL) in a relapse associated with systemic AA amyloidosis. CMV infection in an immunocompromised state with chemotherapy against DLBCL may have been involved in amyloid accumulation. The
serum amyloid A
(
SAA
)1 gene polymorphism, SAA1.2/1.3, might have also been another factor in this case, considering the risk of AA amyloidosis in Japanese patients with rheumatoid arthritis.
...
PMID:AA-type amyloidosis in association with non-Hodgkin's lymphoma following CMV viremia: Autopsy case. 2040 49
