Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q02556 (DNA-binding domain)
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Human Gene/Protein
hLBH 12.3
KIAA1769 12.3
PDIP1beta 12.3
ZNF446 protein 12.3
DNA-binding domain 12.3
THAP0 12.3
TBR1 protein 12.3
ZNF218 12.3
ZNF569 protein 12.3
ZNF328 12.3
A-kinase anchor protein 10 12.3
C17orf64 12.3
MYT1 protein 12.3
NYD-SP10 12.3
A-myb protein 11.7
ETS-domain protein 11.7
RSRFC4 11.5
RSRFR2 11.3
Ets variant gene 6 11.3
EPVH 11.3
FLYWCH1 11.3
ZNF821 11.3
ZNF383 11.3
Sp2 protein 11.3
KIAA0461 11.3
Forkhead-related activator 2 11.3
FOXD4L1 11.3
CGI-55 11.3
Polyamine-modulated factor 1 11.3
DAP4 11.3
FOXD4L6 11.3
B-cell membrane protein 11.3
ZNF419 11.3
RARB protein 11.3
C11orf9 11.3
ZNF446 11.3
NK10 11.0
GBX1 11.0
HZF 11.0
HSF protein 10.9
truncated progesterone receptor 10.9
THAP7 10.7
meiosis-specific RecA-like protein 10.7
SOX22 10.7
C20orf112 10.7
G antigen 6 10.7
KLHL31 10.7
GATA zinc finger domain containing 2A 10.7
CSN7A 10.7
COMMD4 10.7
mutant SRY 10.7
NABC1 10.7
Mahlavu hepatocellular carcinoma 10.7
EWSR2 10.7
IBP1 10.7
ZNF569 10.7
BRD8 protein 10.7
TR2-11 10.5
TAFII55 10.5
LKB1-interacting protein 1 10.3
JARID1C protein 10.3
THG-1 10.3
DMRTA2 10.3
NIPBL protein 10.3
estrogen receptor-related protein 10.3
NUCKS protein 10.3
BEND6 10.3
DJBP 10.3
presenilin-binding protein 10.3
HUEL 10.3
COMMD8 10.3
ZNF649 10.3
transcription factor Pax-5 10.3
pregnancy-specific beta-1-glycoprotein 4 10.3
Histone H1.2 10.3
H-2RIIBP 10.2
PRP21 10.1
NUCKS 10.1
PR domain-containing protein 9 10.1
K6E 10.0
more...
Disease
RIEG2 12.3
SCDO2 11.3
SCDO3 11.3
IRID1 11.3
HPC3 10.3
DFNB35 10.0
HVDRR 9.9
Myeloproliferation 9.5
MSMD 9.5
GCR2 8.9
PPR1 8.8
MDD2 8.8
eyelid infection 8.8
DFNA15 8.1
PFIC3 8.0
BPES 7.8
Vertebral anomalies 7.6
PFIC2 7.5
FUSE 7.4
XY females 7.2
Chronic mucocutaneous candidiasis 7.1
Marshall-Smith syndrome 7.0
PGL3 7.0
Hughes syndrome 7.0
ED4 6.9
testicular feminization 6.9
pediatric liver cancer 6.9
MODY1 6.8
AD2 6.8
Alveolar rhabdomyosarcoma 6.8
HSAN IV 6.8
inv(X) 6.7
conotruncal anomaly face syndrome 6.7
Persistent hyperinsulinemic hypoglycemia of infancy 6.6
congenital hypoplastic anemia 6.6
Desmoplastic small round cell tumor 6.6
Axenfeld-Rieger syndrome 6.6
Reifenstein syndrome 6.5
VDDR 6.5
Enterovirus infection 6.4
PIT 6.4
AD1 6.4
WS4 6.3
Swyer syndrome 6.3
RP9 6.3
AD3 6.3
Drash syndrome 6.2
Epithelioma 6.2
Li-Fraumeni syndrome 6.2
Jacobsen syndrome 6.2
Primary lymphedema 6.1
LBD 6.0
Brachydactyly 6.0
Aeromonas hydrophila infection 6.0
ATE 5.9
erythroblastosis 5.9
vitamin D-resistant rickets 5.9
Pituitary gland 5.9
Pituitary gland 5.9
Pituitary gland 5.9
CRD1 5.9
blepharophimosis-ptosis-epicanthus inversus syndrome 5.8
Nesidioblastosis 5.8
language disorder 5.8
myeloblastosis 5.8
dyserythropoietic anemia 5.8
gonadal dysgenesis 5.8
BLS 5.8
ectodermal dysplasia 5.7
Hopkins syndrome 5.7
CMD1 5.6
NLS 5.6
acute undifferentiated leukemia 5.6
HMR 5.6
cleft lip/palate 5.5
Greig cephalopolysyndactyly syndrome 5.5
TEC 5.5
FANCD1 5.5
Desmoplastic 5.5
hereditary sensory neuropathy 5.5
more...
Symptom
impaired motor coordination 4.7
masculinization 3.5
adenitis 3.1
Fluctuation 3.0
starvation 2.6
hypotonia 2.3
fasciculation 1.9
pallor 1.0
polyuria 0.7
cerebellar ataxia 0.5
acidity 0.4
dystonia 0.2
ENT -0.1
spasticity -0.4
collapse -0.5
ataxia -0.7
thinning -1.2
seizures -1.2
exhaustion -1.5
anorexia -1.5
abdominal pain -1.7
vomiting -1.7
diarrhea -2.0
nausea -2.2
fatigue -2.4
pain -5.7
Drug
1-Methylimidazole 9.1
ETS 7.5
Moco 7.4
K201 7.2
Histidinol 7.0
AraC 6.8
TEL 6.7
GVG 6.5
Ddc 5.7
DNase I 5.5
Orphan 5.2
NLF 5.0
Casodex 4.7
Cinacalcet 4.6
R1881 4.6
Cytidine 4.4
Gel 4.2
Cobalamin 4.2
CTA 4.1
ID2 4.1
ICI 4.0
AC2 3.9
Amifostine 3.8
Retinoic acid 3.7
Tao 3.7
Alanine 3.6
CTT 3.6
lysine 3.5
beta-Galactosidase 3.5
SF6 3.5
BLM 3.5
DEX 3.4
OMP 3.4
Thyroglobulin 3.3
IFN-beta 3.3
Cellulase 3.3
FLP 3.2
CED 3.1
p75 2.9
Lenalidomide 2.9
Asn 2.9
Adenosine deaminase 2.8
Capsicum 2.7
CIA 2.7
AGG 2.6
TAT 2.6
Activin 2.5
Itraconazole 2.3
Reserpine 2.3
Glutathione 2.2
ACT 2.2
Doxycycline 2.2
DHT 2.2
G418 2.1
Estrogens 2.1
Lactose 2.1
DHT 2.1
RFP 2.0
Vitamin B12 2.0
CoCl2 2.0
CoCl2 2.0
Pronase 1.9
Forskolin 1.9
G-CSF 1.9
IPM 1.7
Mutagen 1.7
Vitamin A 1.7
EE2 1.7
Triclosan 1.6
Taxol 1.6
TAC 1.6
lactose 1.6
IFN-gamma 1.5
MRC 1.5
Kenyan 1.5
MAP 1.5
TTC 1.4
EPI 1.2
ABC 1.2
nitroglycerin 1.2
more...
Enzyme
AtIpk2beta 9.0
cathepsin B-like protease 8.5
alpha-aminoadipate aminotransferase 7.9
LexA repressor 7.9
2-haloacid dehalogenase 7.4
steroid 17alpha-hydroxylase 7.4
CobB 7.3
L-2-haloacid dehalogenase 7.0
7-keto-8-aminopelargonic acid 6.8
cholesterol 25-hydroxylase 6.8
dihydroxyacetone synthase 6.8
FabA 6.7
PdxH 6.6
isopenicillin N synthetase 6.5
pyrroline-5-carboxylate dehydrogenase 6.4
diacetyl reductase 6.4
pantothenate synthetase 6.3
protease La 6.3
agmatine deiminase 6.2
hygromycin B phosphotransferase 6.1
proline dehydrogenase 6.0
butyryl-CoA dehydrogenase 5.9
gluconate dehydrogenase 5.8
SsuE 5.7
chloramphenicol acetyltransferase 5.6
histidine kinase 5.6
endonuclease VII 5.6
exonuclease I 5.5
shikimate kinase 5.4
AlkA 5.4
Escherichia coli exonuclease III 5.4
glycoprotease 5.3
nicotinamide mononucleotide adenylyltransferase 5.3
TGT 5.3
oligopeptide permease 5.3
T-protein 5.3
endodeoxyribonuclease 5.2
DNA ligase 5.2
DNA ligase 5.2
tyrosine aminotransferase 5.1
STK 5.1
succinic semialdehyde dehydrogenase 5.0
histone acetyltransferase 5.0
p-hydroxybenzoate hydroxylase 5.0
glycine N-methyltransferase 5.0
MAT 4.9
NMT 4.9
p-hydroxybenzoate hydroxylase 4.9
VIP1 4.9
malate synthase 4.8
PHD 4.8
MAT 4.8
transaldolase 4.6
lysine decarboxylase 4.6
adenylosuccinate synthetase 4.6
RNA polymerase 4.5
PRT 4.5
CO dehydrogenase 4.5
2A protease 4.4
ADE2 4.4
acylphosphatase 4.4
AP lyase 4.4
mercuric reductase 4.4
glutathione S-transferase 4.4
asparagine synthetase 4.3
ClpP 4.3
PARP 4.3
CPL 4.3
luciferase 4.2
nitrite reductase 4.2
HtrA 4.2
nitrite reductase 4.2
nitrite reductase 4.2
lysyl-tRNA synthetase 4.2
p80 4.2
PRE 4.2
p100 4.0
flavin reductase 4.0
uridine phosphorylase 4.0
Rex 4.0
more...
Compound
DBD 9.6
2,4,6-Trichloroanisole 9.1
Pretilachlor 8.4
K486 8.2
AF-2 8.2
Pyrvinium 8.0
RP 1 8.0
2,4-pentadienoic acid 7.9
alpha-isopropylmalate 7.5
Ponasterone A 7.5
Fucosyllactose 7.5
KTS 7.4
DR-1 7.4
Hydroxyflutamide 7.3
ICI 164384 7.2
Nicotinamide riboside 7.1
Cobaltous chloride 7.0
TEL 6.6
hexadecanedioic acid 6.6
Quine 6.6
Maltotriose 6.6
1-methyl-1H-imidazole 6.6
Octopine 6.5
dADP 6.3
ATF 6.2
EPB 6.1
XPA 6.1
XPA 6.1
Cucurbitacin B 6.1
ML-236B 6.1
Distamycin A 6.0
TTNPB 6.0
Butein 6.0
TBP 6.0
Mimosine 5.9
Mimosine 5.8
C2H2 5.8
dodecanedioic acid 5.8
TBP 5.7
Vitexin 5.7
Pregnane 5.6
Mr 30 5.6
GC-1 5.6
TGT 5.6
TEC 5.5
bromoacetic acid 5.5
PRD 5.5
TEA 5.4
TIF 5.4
TEA 5.4
AG-3 5.4
Ellipticine 5.3
A 150 5.2
Cyanogen bromide 5.2
PIPES 5.2
PIPES 5.2
PIPES 5.2
Florid 5.1
C 6 5.0
Poly I 5.0
pyrroline-5-carboxylate 5.0
sulfamic acid 5.0
sulfamic acid 5.0
4-OHT 4.8
Heptachlor 4.8
COS 4.7
APO 4.7
2-methyl-2,4-pentanediol 4.7
Histidine 4.6
zinc 4.6
ADP-ribose 4.6
TET 4.5
TET 4.5
Selenomethionine 4.5
HNS 4.5
DNA 4.5
GAL 4.4
CAT 4.4
CAT 4.4
HAP 4.4
more...