Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q02556 (
DNA-binding domain
)
6,431
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DNA-binding domain
6431
Mol
1303
fused
526
Sep
493
GAL4
436
p53
401
zinc finger
333
transcriptional activator
277
NMR
248
glucocorticoid receptor
229
DNA-binding protein
196
estrogen receptor
188
nuclear receptor
179
leucine zipper
170
androgen receptor
165
polypeptide
155
transcriptional regulator
131
transcriptional repressor
124
histone
115
dimeric
113
SOD
110
AP-1
110
hinge
108
interferon
105
ATP
98
Sp1
93
nuclear protein
89
thyroid hormone
75
chimeric protein
73
DNase I
72
Gen
70
c-Jun
69
helicase
69
telomeric
67
SWI
67
RNA polymerase II
67
threonine
64
ATPase
62
transactivator
61
lymphoid
61
CREB
57
mutant p53
57
p21
56
EBP
55
erythroid
53
basic helix-loop-helix
53
thyroid hormone receptor
52
Pseudomonas
52
progesterone receptor
52
endonuclease
52
p300
52
AP2
51
IRF
49
GST
49
cytokine
49
SRY
47
glutathione S-transferase
45
c-myb
45
alternatively spliced
44
MYB
43
thymus
43
PU.1
42
insulin
42
interacting protein
42
proline-rich
41
proto-oncogene
41
EWS
41
PARP
40
retinoic acid receptor
40
IFN
39
p73
39
CAT
39
unknown function
38
vitamin D receptor
38
ADP
37
E2 protein
37
p65
37
nuclear hormone receptor
37
serum response factor
37
p63
37
more...
Disease
cancer
418
tumor
359
breast cancer
130
tumorigenesis
110
leukemia
103
herpes simplex
71
prostate cancer
63
cold
59
acute myeloid leukemia
55
hepatocellular carcinoma
51
Epstein
50
immunodeficiency
44
carcinogenesis
44
Mycobacterium
42
MCF
40
HIV
40
tuberculosis
39
virus infection
39
Ewing's sarcoma
38
carcinoma
36
mammary tumor
29
leukemogenesis
28
WT1
28
retinoblastoma
27
tumor progression
27
dehydration
24
melanoma
24
Klebsiella
24
Leukemia
21
SDS
21
tumor growth
21
diabetes
20
lymphoma
20
acute lymphoblastic leukemia
19
Kaposi's sarcoma
18
cytomegalovirus
18
osteosarcoma
18
dysplasia
18
cholera
17
Steroids
17
ectodermal dysplasia
16
acute promyelocytic leukemia
15
testicular feminization
15
Li-Fraumeni syndrome
15
uterus
15
myeloid leukemia
15
PML
14
chronic myeloid leukemia
14
gonadal dysgenesis
14
xeroderma pigmentosum
14
LBD
14
bends
13
candidiasis
13
rickets
13
lung cancer
13
neuroblastoma
13
ARF
12
embryonal carcinoma
12
acute leukemia
11
sarcoma
11
myeloblastosis
11
autoimmune disease
11
systemic lupus erythematosus
11
myelodysplastic syndrome
11
developmental delay
11
hepatitis B
11
gastric cancer
11
vaccinia
10
infertility
10
diphtheria
10
colorectal cancer
10
cervical cancer
10
cataract
10
non-small cell lung cancer
9
EEC
9
erythroblastosis
9
hepatitis C
9
Alzheimer's disease
9
adenocarcinoma
9
atherosclerosis
9
more...
Symptom
starvation
31
seizures
7
hypotonia
6
masculinization
6
acidity
4
collapse
4
diarrhea
3
ataxia
2
dystonia
2
vomiting
2
abdominal pain
2
fatigue
2
adenitis
1
spasticity
1
pain
1
Fluctuation
1
thinning
1
pallor
1
cerebellar ataxia
1
nausea
1
anorexia
1
polyuria
1
impaired motor coordination
1
fasciculation
1
ENT
1
exhaustion
1
Drug
lysine
138
ETS
99
DNase I
74
Gel
56
AraC
24
ICI
18
Asn
18
IFN-gamma
17
TEL
16
Dermatol
10
IL-2
10
lactose
10
MAP
9
Retinoic acid
9
Leaf
8
Alanine
7
IFN-beta
6
p75
6
EE2
5
Glutathione
5
CTA
5
nitroglycerin
4
G-CSF
4
Orphan
4
NADH
4
ABC
4
ROS
4
Mutagen
4
R1881
3
TAT
3
Capsicum
3
BLM
3
GVG
3
Cardiovasc
2
Kenyan
2
ENT
2
Biopolymers
2
SF6
2
FLP
2
Vitamin A
2
MRC
2
CaCl2
2
Itraconazole
2
G418
2
DHT
2
Taxol
2
Forskolin
2
DHT
2
Activin
2
ACT
2
CSF
2
CaCl2
2
CaCl2
2
Estrogens
2
DEX
2
CIA
1
Tao
1
IPM
1
Cobalamin
1
Cytidine
1
THF
1
EPI
1
MOF
1
Monit
1
RFP
1
Triclosan
1
Amifostine
1
Thyroglobulin
1
TTC
1
Albumin
1
FAD
1
AGG
1
Glycerol
1
PCB
1
CTT
1
Cellulase
1
beta-Galactosidase
1
Adenosine deaminase
1
ascorbate
1
Angiotensin II
1
more...
Enzyme
RNA polymerase
161
luciferase
145
protein kinase
104
glutathione S-transferase
95
mitogen-activated protein kinase
73
ATPase
63
PARP
53
ERK
52
endonuclease
52
chloramphenicol acetyltransferase
51
catalase
42
trypsin
38
beta-galactosidase
30
focal adhesion kinase
29
DNA polymerase
29
protein kinase C
28
reverse transcriptase
27
proteasome
25
histidine kinase
24
thymidine kinase
21
cdc2
21
DNA ligase
20
DNA ligase
20
topoisomerase
19
chymotrypsin
18
RNase
18
histone acetyltransferase
18
RNase
17
topoisomerase
17
collagenase
16
DNase
13
ACS
13
alkaline phosphatase
13
caspase-3
12
beta-glucuronidase
12
LexA repressor
11
beta-lactamase
11
calcineurin
11
nitrate reductase
10
DNA methyltransferase
10
phosphoenolpyruvate carboxykinase
10
peroxidase
10
MAT
10
prostate-specific antigen
10
nitrate reductase
9
phosphoenolpyruvate carboxykinase
9
MAT
9
nitrate reductase
9
phosphoenolpyruvate carboxykinase
9
tyrosine aminotransferase
9
nitrate reductase
9
nitrate reductase
9
nitrate reductase
9
S1 nuclease
8
aldehyde dehydrogenase
8
thrombin
8
nitrite reductase
7
nitrite reductase
7
nitrite reductase
7
IKK
7
AMPK
7
caspase-1
7
MEK
7
PRE
7
MAP
7
MMP-3
7
papain
7
lysozyme
7
RNase H
6
micrococcal nuclease
6
acid phosphatase
6
alcohol dehydrogenase
5
kinesin
5
aldehyde dehydrogenase
5
transcriptase
5
ribonuclease
5
demethylase
5
ribonuclease
5
urokinase-type plasminogen activator
5
invertase
5
more...
Compound
DNA
3738
Dec
484
zinc
430
lysine
171
cysteine
166
serine
166
arginine
165
alanine
135
leucine
126
His
121
salt
108
phosphate
99
ATP
98
hydrogen
97
tyrosine
96
DBD
94
threonine
90
retinoic acid
89
cAMP
89
proline
80
tryptophan
78
glutamine
74
glucose
71
COS
67
tryptophan
67
tryptophan
66
tryptophan
66
nitrogen
64
NH2
63
Clin
60
oxygen
58
water
55
Asp
50
acetate
47
methionine
42
CAT
39
CAT
39
CAT
39
calcium
38
ADP
38
ADP
37
ADP
37
iron
37
AMP
37
vitamin D
34
sodium
34
copper
33
NAD
32
Phe
32
AF-2
32
ATF
29
ADP-ribose
28
valine
27
Gly
27
urea
25
TEA
24
TEA
24
galactose
23
sulfate
23
ABA
22
glutamate
22
glutamic acid
22
SDS
21
GAL
21
NAD
21
Thyroid
20
aspartic acid
20
C2H2
20
ammonium
20
MDA
20
asparagine
19
Ile
18
Estrogen
18
nitrate
18
Estrogen
18
ICI
18
ethanol
17
TBP
17
TBP
17
aspartic acid
17
more...