Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q02556 (
DNA-binding domain
)
6,431
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DNA-binding domain
6431
Mol
1303
fused
526
Sep
493
GAL4
436
p53
401
zinc finger
333
transcriptional activator
277
NMR
248
glucocorticoid receptor
229
DNA-binding protein
196
estrogen receptor
188
nuclear receptor
179
leucine zipper
170
androgen receptor
165
polypeptide
155
transcriptional regulator
131
transcriptional repressor
124
histone
115
dimeric
113
AP-1
110
SOD
110
hinge
108
interferon
105
ATP
98
Sp1
93
nuclear protein
89
thyroid hormone
75
chimeric protein
73
DNase I
72
Gen
70
helicase
69
c-Jun
69
SWI
67
telomeric
67
RNA polymerase II
67
threonine
64
ATPase
62
transactivator
61
lymphoid
61
more...
Disease
cancer
418
tumor
359
breast cancer
130
tumorigenesis
110
leukemia
103
herpes simplex
71
prostate cancer
63
cold
59
acute myeloid leukemia
55
hepatocellular carcinoma
51
Epstein
50
immunodeficiency
44
carcinogenesis
44
Mycobacterium
42
HIV
40
MCF
40
virus infection
39
tuberculosis
39
Ewing's sarcoma
38
carcinoma
36
mammary tumor
29
leukemogenesis
28
WT1
28
tumor progression
27
retinoblastoma
27
dehydration
24
melanoma
24
Klebsiella
24
tumor growth
21
Leukemia
21
SDS
21
diabetes
20
lymphoma
20
acute lymphoblastic leukemia
19
dysplasia
18
osteosarcoma
18
Kaposi's sarcoma
18
cytomegalovirus
18
Steroids
17
cholera
17
more...
Symptom
starvation
31
seizures
7
hypotonia
6
masculinization
6
acidity
4
collapse
4
diarrhea
3
ataxia
2
dystonia
2
vomiting
2
abdominal pain
2
fatigue
2
adenitis
1
spasticity
1
pain
1
Fluctuation
1
thinning
1
pallor
1
cerebellar ataxia
1
nausea
1
anorexia
1
polyuria
1
impaired motor coordination
1
fasciculation
1
ENT
1
exhaustion
1
Drug
lysine
138
ETS
99
DNase I
74
Gel
56
AraC
24
ICI
18
Asn
18
IFN-gamma
17
TEL
16
IL-2
10
Dermatol
10
lactose
10
MAP
9
Retinoic acid
9
Leaf
8
Alanine
7
p75
6
IFN-beta
6
CTA
5
EE2
5
Glutathione
5
G-CSF
4
ROS
4
NADH
4
nitroglycerin
4
ABC
4
Mutagen
4
Orphan
4
GVG
3
BLM
3
TAT
3
Capsicum
3
R1881
3
Cardiovasc
2
Kenyan
2
Biopolymers
2
ENT
2
Vitamin A
2
SF6
2
Taxol
2
more...
Enzyme
RNA polymerase
161
luciferase
145
protein kinase
104
glutathione S-transferase
95
mitogen-activated protein kinase
73
ATPase
63
PARP
53
endonuclease
52
ERK
52
chloramphenicol acetyltransferase
51
catalase
42
trypsin
38
beta-galactosidase
30
focal adhesion kinase
29
DNA polymerase
29
protein kinase C
28
reverse transcriptase
27
proteasome
25
histidine kinase
24
cdc2
21
thymidine kinase
21
DNA ligase
20
DNA ligase
20
topoisomerase
19
RNase
18
histone acetyltransferase
18
chymotrypsin
18
topoisomerase
17
RNase
17
collagenase
16
DNase
13
alkaline phosphatase
13
ACS
13
beta-glucuronidase
12
caspase-3
12
calcineurin
11
LexA repressor
11
beta-lactamase
11
prostate-specific antigen
10
MAT
10
more...
Compound
DNA
3738
Dec
484
zinc
430
lysine
171
serine
166
cysteine
166
arginine
165
alanine
135
leucine
126
His
121
salt
108
phosphate
99
ATP
98
hydrogen
97
tyrosine
96
DBD
94
threonine
90
retinoic acid
89
cAMP
89
proline
80
tryptophan
78
glutamine
74
glucose
71
COS
67
tryptophan
67
tryptophan
66
tryptophan
66
nitrogen
64
NH2
63
Clin
60
oxygen
58
water
55
Asp
50
acetate
47
methionine
42
CAT
39
CAT
39
CAT
39
ADP
38
calcium
38
more...