Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q02556 (DNA-binding domain)
 6,431 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DNA-binding domain 6431
Mol 1303
fused 526
Sep 493
GAL4 436
p53 401
zinc finger 333
transcriptional activator 277
NMR 248
glucocorticoid receptor 229
DNA-binding protein 196
estrogen receptor 188
nuclear receptor 179
leucine zipper 170
androgen receptor 165
polypeptide 155
transcriptional regulator 131
transcriptional repressor 124
histone 115
dimeric 113
SOD 110
AP-1 110
hinge 108
interferon 105
ATP 98
Sp1 93
nuclear protein 89
thyroid hormone 75
chimeric protein 73
DNase I 72
Gen 70
helicase 69
c-Jun 69
RNA polymerase II 67
telomeric 67
SWI 67
threonine 64
ATPase 62
transactivator 61
lymphoid 61
mutant p53 57
CREB 57
p21 56
EBP 55
erythroid 53
basic helix-loop-helix 53
p300 52
Pseudomonas 52
endonuclease 52
thyroid hormone receptor 52
progesterone receptor 52
AP2 51
cytokine 49
IRF 49
GST 49
SRY 47
glutathione S-transferase 45
c-myb 45
alternatively spliced 44
MYB 43
thymus 43
interacting protein 42
PU.1 42
insulin 42
proto-oncogene 41
proline-rich 41
EWS 41
PARP 40
retinoic acid receptor 40
IFN 39
CAT 39
p73 39
vitamin D receptor 38
unknown function 38
p63 37
ADP 37
serum response factor 37
E2 protein 37
nuclear hormone receptor 37
p65 37
orphan nuclear receptor 36
homeobox 36
AMP 36
histone deacetylase 36
TATA-binding protein 35
AML1 34
repressor protein 34
ubiquitin 33
c-myc 33
ERF 33
hormone receptor 32
poly(ADP-ribose) polymerase 32
tumour suppressor 32
c-fos 32
zinc finger protein 32
histone H3 30
transcriptional factor 30
Oct-1 30
endoplasmic reticulum 30
MDM2 29
Fli-1 29
ATF 29
CBP 28
RAR 28
single-stranded DNA-binding protein 28
integrase 27
mer 27
transcriptional coactivator 27
STAT1 27
phosphatase 26
TFIIB 26
mineralocorticoid receptor 25
c-Myc 25
proteasome 24
putative transcription factor 24
orphan receptor 24
Poly(ADP-ribose) polymerase 23
IRF-1 23
peroxisome proliferator-activated receptor 23
ORF 23
Pax 22
MyoD 22
beta-catenin 22
AP1 22
SHP 22
NAD 21
HSF1 21
TEL 21
Transcription factor 21
A. nidulans 21
TCF 21
GAL 21
SDS 21
WT1 21
Pol 21
thymidine kinase 21
p50 21
rhabdomyosarcoma 20
cryptic 20
IRF8 20
C2H2 20
high mobility group box 1 20
CBF 20
cyclin D1 20
X-linked 20
GATA-1 19
GAL1 19
TFIID 19
STAT 19
BRCA2 19
osteocalcin 19
ras 19
RNA polymerase I 19
CD4 19
MAPK 19
transcription factor IIIA 18
caspase-3 18
cage 18
E12 18
peroxisome proliferator-activated receptor gamma 18
more...
Disease
cancer 418
tumor 359
breast cancer 130
tumorigenesis 110
leukemia 103
herpes simplex 71
prostate cancer 63
cold 59
acute myeloid leukemia 55
hepatocellular carcinoma 51
Epstein 50
carcinogenesis 44
immunodeficiency 44
Mycobacterium 42
MCF 40
HIV 40
virus infection 39
tuberculosis 39
Ewing's sarcoma 38
carcinoma 36
mammary tumor 29
WT1 28
leukemogenesis 28
retinoblastoma 27
tumor progression 27
melanoma 24
dehydration 24
Klebsiella 24
tumor growth 21
Leukemia 21
SDS 21
diabetes 20
lymphoma 20
acute lymphoblastic leukemia 19
dysplasia 18
Kaposi's sarcoma 18
osteosarcoma 18
cytomegalovirus 18
cholera 17
Steroids 17
ectodermal dysplasia 16
uterus 15
Li-Fraumeni syndrome 15
acute promyelocytic leukemia 15
myeloid leukemia 15
testicular feminization 15
LBD 14
xeroderma pigmentosum 14
PML 14
gonadal dysgenesis 14
chronic myeloid leukemia 14
candidiasis 13
bends 13
rickets 13
lung cancer 13
neuroblastoma 13
embryonal carcinoma 12
ARF 12
sarcoma 11
gastric cancer 11
myeloblastosis 11
developmental delay 11
myelodysplastic syndrome 11
acute leukemia 11
hepatitis B 11
systemic lupus erythematosus 11
autoimmune disease 11
infertility 10
diphtheria 10
vaccinia 10
cataract 10
colorectal cancer 10
cervical cancer 10
non-small cell lung cancer 9
EEC 9
atherosclerosis 9
erythroblastosis 9
Alzheimer's disease 9
adenocarcinoma 9
hepatitis C 9
mole 8
osteoporosis 8
type 2 diabetes 8
anemia 8
NLS 8
developmental disabilities 8
squamous cell carcinoma 8
metastases 8
erythroleukemia 8
autism 8
abdominal aortic aneurysm 7
HMR 7
mole 7
bacterial infection 7
AAA 7
pheochromocytoma 7
sepsis 7
Fox 7
cleft palate 7
rhabdomyosarcoma 7
PDB 7
heart disease 7
fibrosarcoma 7
infectious diseases 7
AIDS 7
plaque 7
CAP 7
neoplastic transformation 7
PIT 7
language disorder 7
ovarian cancer 7
papilloma 6
pneumonia 6
myeloproliferative disorders 6
Rous sarcoma 6
cleft lip/palate 6
worms 6
Desmoplastic small round cell tumor 6
Yersinia 6
colon cancer 6
pancreatic cancer 6
multiple myeloma 6
hypogonadotropic hypogonadism 6
varicella 6
Klippel-Trenaunay syndrome 6
insulinoma 6
endometrial cancer 6
hyperparathyroidism 6
hormone deficiency 6
genetic disorder 6
FUS 6
ATM 6
thrombocytopenia 6
liposarcoma 6
Fanconi 6
HP1 6
hepatitis 6
CHARGE syndrome 5
influenza 5
B-cell lymphoma 5
LAP 5
chondrosarcoma 5
stomatitis 5
Hippel 5
fits 5
Huntington's disease 5
Rett syndrome 5
LIN 5
Schistosoma mansoni 5
Waardenburg syndrome 5
TEC 5
hypertension 5
NAME 5
XY females 5
chronic lymphocytic leukemia 5
obesity 5
glioma 5
glioblastoma 5
ABL 5
Recruitment 5
more...
Symptom
starvation 31
seizures 7
hypotonia 6
masculinization 6
acidity 4
collapse 4
diarrhea 3
ataxia 2
dystonia 2
vomiting 2
abdominal pain 2
fatigue 2
adenitis 1
spasticity 1
pain 1
Fluctuation 1
thinning 1
pallor 1
cerebellar ataxia 1
nausea 1
anorexia 1
polyuria 1
impaired motor coordination 1
fasciculation 1
ENT 1
exhaustion 1
Drug
lysine 138
ETS 99
DNase I 74
Gel 56
AraC 24
Asn 18
ICI 18
IFN-gamma 17
TEL 16
Dermatol 10
IL-2 10
lactose 10
MAP 9
Retinoic acid 9
Leaf 8
Alanine 7
IFN-beta 6
p75 6
EE2 5
Glutathione 5
CTA 5
Mutagen 4
ROS 4
G-CSF 4
Orphan 4
ABC 4
nitroglycerin 4
NADH 4
BLM 3
TAT 3
R1881 3
Capsicum 3
GVG 3
Cardiovasc 2
Kenyan 2
ENT 2
Biopolymers 2
FLP 2
SF6 2
CSF 2
CaCl2 2
Vitamin A 2
CaCl2 2
ACT 2
Activin 2
Itraconazole 2
CaCl2 2
DHT 2
G418 2
DHT 2
Forskolin 2
MRC 2
Taxol 2
Estrogens 2
DEX 2
CIA 1
Tao 1
IPM 1
Cobalamin 1
Cytidine 1
THF 1
EPI 1
MOF 1
Monit 1
RFP 1
Triclosan 1
Amifostine 1
Thyroglobulin 1
TTC 1
Albumin 1
FAD 1
AGG 1
CED 1
Glycerol 1
PCB 1
Ddc 1
CTT 1
AC2 1
Vitamin B12 1
Doxycycline 1
Cellulase 1
TAC 1
beta-Galactosidase 1
Adenosine deaminase 1
ascorbate 1
Growth hormone 1
Angiotensin II 1
Reserpine 1
caffeine 1
Glucagon 1
vitamin E 1
K201 1
PTH 1
Casodex 1
AZT 1
Lactose 1
HCH 1
Histidinol 1
CoCl2 1
NLF 1
1-Methylimidazole 1
CoCl2 1
Growth hormone 1
Cinacalcet 1
niacin 1
Pronase 1
OMP 1
ID2 1
Moco 1
Lenalidomide 1
Enzyme
RNA polymerase 161
luciferase 145
protein kinase 104
glutathione S-transferase 95
mitogen-activated protein kinase 73
ATPase 63
PARP 53
endonuclease 52
ERK 52
chloramphenicol acetyltransferase 51
catalase 42
trypsin 38
beta-galactosidase 30
focal adhesion kinase 29
DNA polymerase 29
protein kinase C 28
reverse transcriptase 27
proteasome 25
histidine kinase 24
cdc2 21
thymidine kinase 21
DNA ligase 20
DNA ligase 20
topoisomerase 19
histone acetyltransferase 18
chymotrypsin 18
RNase 18
RNase 17
topoisomerase 17
collagenase 16
ACS 13
alkaline phosphatase 13
DNase 13
beta-glucuronidase 12
caspase-3 12
LexA repressor 11
beta-lactamase 11
calcineurin 11
MAT 10
nitrate reductase 10
DNA methyltransferase 10
prostate-specific antigen 10
peroxidase 10
phosphoenolpyruvate carboxykinase 10
phosphoenolpyruvate carboxykinase 9
phosphoenolpyruvate carboxykinase 9
nitrate reductase 9
nitrate reductase 9
nitrate reductase 9
nitrate reductase 9
MAT 9
tyrosine aminotransferase 9
nitrate reductase 9
aldehyde dehydrogenase 8
S1 nuclease 8
thrombin 8
papain 7
MAP 7
nitrite reductase 7
MMP-3 7
nitrite reductase 7
IKK 7
AMPK 7
PRE 7
nitrite reductase 7
MEK 7
caspase-1 7
lysozyme 7
RNase H 6
acid phosphatase 6
micrococcal nuclease 6
alcohol dehydrogenase 5
ribonuclease 5
aldehyde dehydrogenase 5
kinesin 5
invertase 5
ribonuclease 5
demethylase 5
firefly luciferase 5
urokinase-type plasminogen activator 5
PHD 5
transcriptase 5
phosphodiesterase 4
aldehyde dehydrogenase 4
chaperonin 4
gamma-glutamyl transpeptidase 4
superoxide dismutase 4
proline dehydrogenase 4
proteinase K 4
APC 4
cathepsin D 4
aldehyde dehydrogenase 4
phosphatidylinositol 3-kinase 4
alpha-amylase 4
aldehyde dehydrogenase 4
TGT 4
acyl-CoA oxidase 3
ClpP 3
malate synthase 3
TAT 3
urease 3
adenosine deaminase 3
pyruvate kinase 3
CYP7A1 3
adenosine deaminase 3
complex I 3
PRA 3
NADPH oxidase 3
guanylate cyclase 3
matrix metalloproteinase 2 3
GSK 3
Rex 3
p100 3
caspase-8 3
urease 3
GAS 3
isocitrate lyase 3
phosphoglycerate kinase 3
hormone-sensitive lipase 3
SPC 2
endonuclease VII 2
cytochrome oxidase 2
matrix metalloproteinase 9 2
nitrogenase 2
ribonucleotide reductase 2
ribonucleotide reductase 2
phospholipase D 2
alcohol oxidase 2
lipase 2
lysine decarboxylase 2
asparagine synthetase 2
thermolysin 2
xylanase 2
CobB 2
Pla 2
PKG 2
21-hydroxylase 2
neutrophil elastase 2
TOR 2
cellulase 2
xylanase 2
peroxiredoxin 2
deaminase 2
N-acetyltransferase 2
adenylate cyclase 2
exonuclease I 2
MEKK1 2
CYP3A4 2
protein phosphatase 2A 2
ATP synthase 2
dihydrofolate reductase 2
PAL 2
pyrroline-5-carboxylate dehydrogenase 2
HtrA 2
glutamate dehydrogenase 2
furin 2
ascorbate oxidase 2
p80 2
histone demethylase 2
succinic semialdehyde dehydrogenase 2
more...
Compound
DNA 3738
Dec 484
zinc 430
lysine 171
cysteine 166
serine 166
arginine 165
alanine 135
leucine 126
His 121
salt 108
phosphate 99
ATP 98
hydrogen 97
tyrosine 96
DBD 94
threonine 90
retinoic acid 89
cAMP 89
proline 80
tryptophan 78
glutamine 74
glucose 71
tryptophan 67
COS 67
tryptophan 66
tryptophan 66
nitrogen 64
NH2 63
Clin 60
oxygen 58
water 55
Asp 50
acetate 47
methionine 42
CAT 39
CAT 39
CAT 39
calcium 38
ADP 38
iron 37
ADP 37
AMP 37
ADP 37
sodium 34
vitamin D 34
copper 33
AF-2 32
NAD 32
Phe 32
ATF 29
ADP-ribose 28
valine 27
Gly 27
urea 25
TEA 24
TEA 24
galactose 23
sulfate 23
glutamic acid 22
glutamate 22
ABA 22
SDS 21
GAL 21
NAD 21
C2H2 20
ammonium 20
aspartic acid 20
Thyroid 20
MDA 20
asparagine 19
Ile 18
ICI 18
Estrogen 18
nitrate 18
Estrogen 18
aspartic acid 17
ethanol 17
aspartic acid 17
TBP 17
aspartic acid 17
TBP 17
glycerol 16
cadmium 16
TEL 16
PEG 16
PAS 16
ABA 15
Mg2+ 15
XPA 14
XPA 14
ACS 13
ACS 13
nickel 13
nitric oxide 12
pyrimidine 12
isoleucine 12
isoleucine 12
Androgen 12
pyrimidine 12
salicylic acid 12
EDTA 11
EDTA 11
TOF 11
TNF 10
cobalt 10
GSH 10
GSH 10
N-acetylcysteine 10
PAR 9
H2O2 9
VP-16 9
Ethylene 9
PEG 9
aldosterone 9
nicotinamide 9
manganese 9
ACTH 9
TPA 8
GMP 8
TPA 8
CAM 8
xylose 8
GlcNAc 8
chromate 8
TSH 8
BCR 8
TEM 7
APO 7
Alanine 7
CAP 7
PDB 7
adenosylmethionine 7
SET 7
hydroxylamine 7
Dexamethasone 7
Histidine 7
MAP 7
GTP 7
hydroxylamine 7
homoserine 7
homoserine 7
AAA 7
homoserine 7
THP 7
pyrene 7
CAP 7
Panam 7
THP 7
TAR 7
CoA 7
NTA 7
ABL 6
Estradiol 6
boron 6
GABA 6
potassium 6
cGMP 6
A 1 6
GABA 6
more...