Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P80404 (GABA transaminase)
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Human Gene/Protein
GABA transaminase 15.3
JAKMIP2 15.3
FLJ35024 15.3
COPS7B 13.7
pyruvate dehydrogenase (lipoamide) beta 13.3
Succinate semialdehyde dehydrogenase 13.0
ERMP1 13.0
succinic semialdehyde dehydrogenase 12.9
succinate semialdehyde dehydrogenase 12.8
TMEM114 12.7
succinate-semialdehyde dehydrogenase 12.6
SSADH 12.4
ALDH6A1 12.1
BFAR 12.1
PRKCDBP 12.0
Succinic semialdehyde dehydrogenase 12.0
HNRNPH2 11.6
SUCLG1 11.6
D-3-aminoisobutyrate-pyruvate aminotransferase 11.5
4-aminobutyrate aminotransferase 11.4
WBSCR22 11.3
ALDH5A1 11.2
NDUFA10 11.1
GAT-2 11.1
RNASEH1 11.1
A2BP1 11.0
EPHA6 10.9
glutamate decarboxylase 10.8
DAPP1 10.7
FBXL4 10.6
EHHADH 10.6
cysteine sulfinic acid decarboxylase 10.6
NAD+-isocitrate dehydrogenase 10.6
EMP2 10.5
alpha-albumin 10.5
SUCLA2 10.5
EPHA5 10.4
GAD2 10.4
AGK 10.4
GAT2 10.4
UBN1 10.4
GAD 10.3
dGK 10.3
NRCAM 10.3
GABRD 10.3
MPV17 10.2
ALDH1B1 10.2
GABA transporter 10.0
PLA2G1B 10.0
nSMase2 10.0
GABA-B receptor 10.0
GABBR1 9.9
GAD1 9.9
G3BP2 9.9
TBX6 9.9
AKR7A2 9.8
KCND3 9.8
KRS 9.8
CRMP1 9.8
DGUOK 9.7
EVC2 9.6
betaine/GABA transporter 9.6
MRTF-B 9.6
POP2 9.6
GABRB2 9.5
GAT-3 9.5
glutamic acid decarboxylase 9.5
MDH1 9.4
GABRA5 9.4
PMCA3 9.4
KCNJ1 9.4
EHD2 9.4
THPO 9.4
PLA2G2A 9.4
PSORT 9.3
AKR1A1 9.3
GAD67 9.3
TK2 9.3
ABCA2 9.3
dCK 9.2
RRM2B 9.1
GABA 9.1
GRIN2A 9.0
AGXT 8.9
isocitric dehydrogenase 8.9
DAO 8.9
GDH 8.8
CHMP2B 8.8
betac 8.8
TCL1A 8.8
GOX 8.7
KCNJ10 8.7
EVC 8.7
PolB 8.7
GABA(B) receptor 8.7
ubiquilin 8.6
GAD65 8.6
Glutaminase 8.6
BHMT 8.5
KAT2 8.5
PFL 8.4
FOXF1 8.4
MAP4K4 8.4
p53R2 8.4
TWINKLE 8.4
2-oxoglutarate dehydrogenase 8.3
HOT 8.3
CYP4A11 8.2
PMM2 8.2
SV2A 8.2
ALOX5 8.2
GAT1 8.2
PMCA2 8.1
Diamine oxidase 8.1
VLDLR 8.1
polyamine oxidase 8.1
pyrroline-5-carboxylate synthetase 8.0
BCATm 8.0
ATP1A1 8.0
oxoglutarate 8.0
glutaminase 7.9
HTR1B 7.9
GABRB3 7.9
MME 7.9
CNR1 7.8
vesicular GABA transporter 7.8
PDZK1 7.8
PLP 7.8
ALR 7.8
sarcosine oxidase 7.8
fatty acid hydroxylase 7.8
gamma-amino butyric acid 7.7
PLP1 7.7
serotonin N-acetyltransferase 7.7
ALOX15 7.7
noradrenaline transporter 7.7
arginine decarboxylase 7.6
CPT1A 7.6
diamine oxidase 7.6
ornithine aminotransferase 7.6
alpha-ketoglutarate dehydrogenase 7.6
peroxiredoxin 1 7.5
ASS 7.5
glutamic dehydrogenase 7.5
Tryptophan hydroxylase 7.5
CKB 7.5
EOS 7.5
PSEN2 7.4
DNA2 7.4
TC1 7.4
CDH2 7.4
AMPS 7.4
UCH-L1 7.4
DMRT1 7.4
LDH-B 7.3
Alanine aminotransferase 7.3
MFN2 7.3
TK1 7.3
L-FABP 7.2
PDIA3 7.2
more...
Disease
Hyper-beta-alaninemia 13.7
Succinic semialdehyde dehydrogenase deficiency 12.6
GAD 9.9
Myelodysplastic Syndrome 9.9
audiogenic seizure 9.0
Acute encephalopathy 8.9
Medulla 8.8
KRS 8.5
catatonic schizophrenia 8.4
hyperglycinemia 8.2
hypo-osmolality 7.8
Inborn errors of metabolism 7.7
EOS 7.5
EOS 7.5
diabetic hyperglycemia 7.5
complex partial seizures 7.4
Ellis-van Creveld syndrome 7.3
cocaine addiction 7.1
Lennox-Gastaut syndrome 7.1
ornithine transcarbamylase deficiency 7.1
SPS 7.0
Lennox-Gastaut syndrome 6.8
aminoaciduria 6.6
SPS 6.6
propionic acidemia 6.6
premenstrual dysphoric disorder 6.4
PME 6.2
hepatic coma 6.2
PTD 6.1
SCH 6.0
petit mal 6.0
moderate mental retardation 6.0
OPA1 5.9
lymphogranuloma venereum 5.8
paranoid schizophrenia 5.8
catalepsy 5.7
generalized seizure 5.6
tardive dyskinesia 5.6
epilepsy 5.6
HCI 5.5
hyperosmolality 5.5
vitamin E deficiency 5.5
fits 5.4
trichotillomania 5.4
panic disorder 5.3
PIC 5.3
GCE 5.3
Venezuelan equine encephalitis 5.2
SCD 5.1
febrile convulsions 5.1
Esophageal squamous cell carcinoma 4.9
Rift Valley fever 4.8
porphyria 4.8
neoplastic process 4.8
cocaine abuse 4.8
Wuchereria 4.7
disinhibition 4.7
CSA 4.6
adrenocortical carcinoma 4.6
Cerebellum 4.5
fragile X syndrome 4.5
status epilepticus 4.5
tuberous sclerosis 4.4
DBA 4.3
developmental delay 4.3
Nelson 4.3
temporal lobe epilepsy 4.3
hyperprolactinemia 4.3
drug withdrawal 4.1
panic attacks 4.1
Cushing's disease 4.0
anhedonia 3.9
uterine leiomyoma 3.9
emotional stress 3.9
apraxia 3.8
listeriosis 3.8
African trypanosomiasis 3.8
ACP 3.8
anxiety disorders 3.7
Hepatocellular carcinoma 3.7
rickets 3.6
Huntington's disease 3.6
sleep disorders 3.5
PCP 3.5
astrocytoma 3.5
iron deficiency 3.5
meninges 3.5
encephalopathy 3.5
mental retardation 3.4
mental retardation 3.4
sexual dysfunction 3.3
hypoglycemia 3.3
migraine 3.3
movement disorder 3.2
brain metastases 3.2
MRS 3.1
Disorder 3.1
parkinsonism 3.1
HCG 3.1
brain atrophy 3.1
Posterior 2.9
PSA 2.9
Pituitary 2.9
amnesia 2.9
sleep disturbances 2.9
suicide 2.9
conjunctiva 2.9
vitamin D deficiency 2.9
affective disorder 2.8
psychosis 2.8
PCC 2.8
hyperphagia 2.7
alcoholism 2.7
tetanus 2.7
drug addiction 2.7
autism 2.6
NAME 2.6
Autism 2.6
neuroblastoma 2.5
duodenal ulcer 2.5
prematurity 2.5
memory impairment 2.5
aggression 2.5
myelodysplastic syndrome 2.4
hallucinations 2.4
peptic ulcer 2.3
schizophrenia 2.2
Still 2.2
ADHD 2.2
neurological disease 2.1
depression 2.1
cold 2.0
ischemia 1.8
prolapse 1.8
sickle cell disease 1.8
myopathy 1.8
brain tumor 1.7
substance abuse 1.6
addiction 1.5
bipolar disorder 1.5
pheochromocytoma 1.5
respiratory failure 1.4
coma 1.4
cerebral ischemia 1.3
hepatocellular carcinoma 1.2
pulmonary hypertension 1.1
amyotrophic lateral sclerosis 1.1
meningitis 0.9
multiple sclerosis 0.9
Alzheimer's disease 0.9
renal cell carcinoma 0.9
lung carcinoma 0.8
West 0.7
autoimmune disease 0.7
infertility 0.6
herpes simplex 0.5
hyperglycemia 0.5
tumor growth 0.5
glioma 0.4
dysplasia 0.3
more...
Symptom
Subjective tinnitus 9.2
impaired motor coordination 7.7
tonic seizure 7.6
Psychiatric symptoms 7.0
POA 6.3
partial seizure 5.9
hypotonia 5.8
clonus 5.8
seizures 5.7
eds 5.3
lethargy 4.8
neuralgia 4.5
myoclonus 4.2
skin irritation 4.2
bradykinesia 4.1
tachypnea 4.0
ataxia 3.9
tinnitus 3.6
ophthalmoplegia 3.6
hypothermia 3.5
insomnia 3.5
sleepiness 3.2
spasticity 2.6
anorexia 2.6
analgesia 2.5
vertigo 2.5
dystonia 2.3
tremor 2.1
distraction 2.1
constipation 2.0
headache 1.9
agitation 1.7
starvation 1.7
anesthesia 0.9
vomiting 0.3
diarrhea -0.5
pain -0.7
Drug
Fengabine 13.0
GVG 12.9
Ganaxolone 11.0
Sodium valproate 9.8
Stiripentol 9.5
Rufinamide 9.4
Gabapentin 8.8
Pyridoxal phosphate 8.2
Abamectin 8.1
Quisqualate 7.8
pyridoxal phosphate 7.8
Deferasirox 7.7
Ethylenediamine 7.6
Compound 9 7.3
Pyridoxal 7.3
Apomorphine 6.6
DPA 6.6
Aminoguanidine 6.6
Pregabalin 6.5
OMP 6.4
Glutamic acid 6.3
Sulpiride 6.1
Helium 6.1
Pilocarpine 6.0
Kainic acid 6.0
ALA 5.8
TEL 5.7
niacin 5.4
Isoniazid 5.4
Vitamin B 5.0
Phenytoin 4.9
balanced salt solution 4.7
Activin 4.6
PCP 4.5
Frontal 4.3
Propofol 4.3
Estrogens 4.2
CDP 4.1
L-tyrosine 4.1
NADH 3.7
Vitamin E 3.6
CSF 3.6
Glucagon 3.4
Spectrum 3.3
Ethanol 3.0
citric acid 3.0
FAD 2.9
NH3 2.5
MAP 2.4
Spectrum 2.4
caffeine 1.9
Asn 1.8
lysine 1.5
Gel 1.4
vitamin E 1.2
Nephron 1.2
ROS 1.1
Leaf 0.9
ascorbate 0.8
Enzyme
GABA transaminase 14.9
EC 1.1.1.15 14.3
hydroxyacid-oxoacid transhydrogenase 13.5
EC 1.2.1.16 13.1
succinic semialdehyde dehydrogenase 12.9
beta-alanine-pyruvate aminotransferase 12.7
D-3-aminoisobutyrate-pyruvate aminotransferase 12.1
Xsc 11.3
glutamate decarboxylase 10.9
alpha-aminoadipate aminotransferase 10.9
2-oxoglutarate decarboxylase 10.4
propionyl-CoA synthetase 10.2
acetylornithine aminotransferase 10.0
desulfinase 9.8
pantothenate synthetase 9.3
glutamic dehydrogenase 8.5
branched-chain aminotransferase 8.5
ornithine aminotransferase 8.1
polyamine oxidase 8.0
sarcosine oxidase 7.9
glutaminase 7.9
arginine decarboxylase 7.8
alpha-ketoglutarate dehydrogenase 7.8
adenylosuccinate lyase 7.8
arginine decarboxylase 7.6
glutamate dehydrogenase 7.3
glutamate dehydrogenase 7.3
glutamate dehydrogenase 7.3
S-adenosylmethionine decarboxylase 7.1
diamine oxidase 7.0
proline dehydrogenase 7.0
alanine racemase 7.0
4CL 7.0
arylalkylamine N-acetyltransferase 6.9
propionyl-CoA carboxylase 6.9
propionyl-CoA carboxylase 6.9
SPS 6.6
succinyl-CoA synthetase 6.6
glutamine synthetase 6.6
carnitine acetyltransferase 6.6
cyclohydrolase 6.5
acetyl-CoA synthetase 6.5
aldehyde reductase 6.3
aldehyde reductase 6.3
DOPA decarboxylase 6.3
aldehyde reductase 6.3
aromatic L-amino acid decarboxylase 6.2
serine hydroxymethyltransferase 6.1
isocitrate dehydrogenase 6.0
monoamine oxidase 5.8
ascorbate oxidase 5.7
prolyl endopeptidase 5.7
ornithine decarboxylase 5.7
dihydropyrimidine dehydrogenase 5.6
BAT 5.6
tryptophan hydroxylase 5.5
SCS 5.3
aspartate aminotransferase 5.3
citrate synthase 5.2
fumarase 5.2
isocitrate dehydrogenase 5.1
N-acetyltransferase 5.1
dihydropyrimidine dehydrogenase 5.0
choline acetyltransferase 5.0
tyrosine hydroxylase 4.9
aldehyde dehydrogenase 4.8
aldehyde dehydrogenase 4.8
aldehyde dehydrogenase 4.8
alanine aminotransferase 4.8
pyruvate carboxylase 4.7
succinate dehydrogenase 4.6
phosphoenolpyruvate carboxylase 4.6
ornithine transcarbamylase 4.6
aldehyde dehydrogenase 4.6
thymidylate synthase 4.5
MPP 4.4
PCP 4.4
NADH dehydrogenase 4.2
aldehyde dehydrogenase 4.2
deaminase 4.0
glucose-6-phosphate dehydrogenase 4.0
hexokinase 3.9
pyruvate dehydrogenase 3.9
ascorbate peroxidase 3.8
ribonucleotide reductase 3.8
ribonucleotide reductase 3.8
aldose reductase 3.6
pyruvate dehydrogenase 3.5
pyruvate dehydrogenase 3.5
nitrate reductase 3.4
nitrate reductase 3.4
enolase 3.4
nitrate reductase 3.4
nitrate reductase 3.4
arginase 3.4
nitrate reductase 3.4
adenylate cyclase 3.4
nitrate reductase 3.4
NADPH-diaphorase 3.4
NO synthase 3.4
phosphoenolpyruvate carboxykinase 3.3
phosphoenolpyruvate carboxykinase 3.3
CPT 3.1
malate dehydrogenase 3.1
phosphoenolpyruvate carboxykinase 3.1
pyruvate kinase 3.0
CPR 3.0
acetylcholinesterase 2.8
phosphoinositide 3-kinase 2.8
diaphorase 2.8
kallikrein 2.7
AST 2.7
CYP3A4 2.7
NOS 2.5
lactate dehydrogenase 2.5
carbonic anhydrase 2.4
cytochrome oxidase 2.2
complex I 2.2
alcohol dehydrogenase 2.1
glutathione reductase 2.1
NADPH oxidase 2.0
peroxidase 1.9
phosphatidylinositol 3-kinase 1.9
NADPH oxidase 1.8
acid phosphatase 1.7
catalase 1.5
beta-galactosidase 1.5
reverse transcriptase 1.4
RNase 1.3
RNase 1.2
phosphodiesterase 1.1
luciferase 1.1
ATPase 0.9
glutathione peroxidase 0.9
ACS 0.6
superoxide dismutase 0.5
ERK 0.3
RNA polymerase 0.2
caspase-3 0.2
renin 0.2
mitogen-activated protein kinase -0.2
protein kinase C -0.3
Compound
3-phenylpentanoic acid 15.3
3-phenylpentanoic acid 15.3
Gabaculine 13.3
3-chloropropanoic acid 13.0
Vigabatrin 13.0
2-aminoethylphosphonic acid 11.7
3-MPA 11.4
Canaline 11.1
TXP 11.1
2-pentenoic acid 10.9
Homotaurine 10.8
THIP 10.7
Phenelzine 10.6
Phenelzine 10.6
4-bromobenzaldehyde 10.4
4-bromobenzaldehyde 10.4
4-bromobenzaldehyde 10.4
4-bromobenzaldehyde 9.8
4-methylpentanoic acid 9.8
Pyrithiamine 9.8
4-hydroxybenzyl alcohol 9.8
4-oxobutanoic acid 9.7
cinnamyl acetate 9.6
Tiagabine 9.6
1-penten-3-ol 9.3
gamma-aminobutyric acid 9.2
Muscimol 9.2
5-aminopentanoic acid 9.2
4-hydroxybenzaldehyde 9.2
4-hydroxybenzaldehyde 9.2
4-hydroxybenzaldehyde 9.1
4-hydroxybenzaldehyde 9.1
GABA 9.1
4-hydroxy-3-methoxybenzaldehyde 9.1
4-hydroxy-3-methoxybenzaldehyde 9.1
GABA 9.1
DBB 9.0
Ethosuximide 8.9
4-hydroxybenzaldehyde 8.9
gamma-hydroxybutyric acid 8.9
D-Cycloserine 8.8
L-2,4-diaminobutyric acid 8.8
2-pyrrolidinone 8.8
2-pentene 8.8
2-Chloroadenosine 8.7
2-Chloroadenosine 8.7
Semicarbazide 8.7
4-hydroxy-3-methoxybenzaldehyde 8.6
beta-alanine 8.6
TCTP 8.6
4-bromobenzaldehyde 8.5
HBA 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.5
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
2-hydroxybenzaldehyde 8.4
1,4-butanediamine 8.4
Roxarsone 8.3
Piperidine 8.3
2-oxoglutarate 8.3
2-hydroxybenzaldehyde 8.2
Felbamate 8.2
cysteate 8.1
Clobazam 8.1
2-hydroxybenzaldehyde 8.1
2-pyrrolidinone 8.1
isonicotinic acid 8.1
Bicuculline 7.9
Picrotoxin 7.9
Picrotoxin 7.9
Baclofen 7.9
vinyl 7.9
2-hydroxybenzaldehyde 7.8
PLP 7.8
Lamotrigine 7.8
Tetracaine 7.8
3-methylbutanoic acid 7.8
PMP 7.7
PMP 7.7
Oxcarbazepine 7.7
PMP 7.6
Clonazepam 7.5
2-hydroxybenzaldehyde 7.5
EOS 7.5
Vanillin 7.4
Valproic acid 7.4
Flumazenil 7.3
Levetiracetam 7.3
Valproic acid 7.3
Pyridoxal 7.3
Lithium chloride 7.2
Taurocholate 7.1
Cypermethrin 7.1
AIB 7.1
pentanoic acid 7.0
2-phenylethylamine 7.0
Putrescine 7.0
Chlordiazepoxide 6.9
2-furaldehyde 6.9
MME 6.9
Pyridoxine 6.7
Hydrazine 6.7
2-furaldehyde 6.7
butyric acid 6.6
Ether 6.6
Ether 6.6
Lorazepam 6.6
butyric acid 6.5
succinic acid 6.5
succinic acid 6.5
succinic acid 6.5
succinic acid 6.5
Veratridine 6.5
phenylacetaldehyde 6.5
Baicalein 6.4
hydroxyglutarate 6.4
Imipramine 6.4
Imipramine 6.4
butyric acid 6.4
OMP 6.3
Carnosine 6.3
Aminophylline 6.2
CPP 6.2
DPA 6.2
DPA 6.2
CPP 6.2
3-hydroxybutyric acid 6.2
succinic acid 6.1
NMP 6.1
5-Aza-2'-deoxycytidine 6.1
Topiramate 6.1
DPA 6.0
Pilocarpine 6.0
DPA 6.0
Flavonoid 6.0
DPA 6.0
glutamate 6.0
5-hydroxytryptophan 6.0
Glutamate 6.0
Heroin 6.0
Kainic acid 6.0
Kainic acid 6.0
Glutamine 5.9
Propionate 5.9
DPA 5.9
aminomethyl 5.8
CNQX 5.8
more...