Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P80404 (GABA transaminase)
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Human Gene/Protein
GABA transaminase 786
GABA 464
glutamate decarboxylase 89
glutamic acid decarboxylase 69
GAD 58
Sep 52
succinic semialdehyde dehydrogenase 39
GABA transporter 22
Mol 20
GAD67 18
aspartate aminotransferase 18
olfactory 16
glutamate dehydrogenase 15
GABA(A) receptor 15
ATP 13
GABA(B) receptor 13
GAD65 13
tyrosine hydroxylase 12
glutamine synthetase 12
succinate semialdehyde dehydrogenase 12
Gen 12
glutaminase 11
alanine aminotransferase 11
reductase 10
CSF 9
NAD 9
NMR 8
ornithine decarboxylase 8
SCH 8
SSADH 8
NMDA receptor 7
5-hydroxytryptamine 7
GDH 7
ionotropic 7
PLP 7
NADH 7
4-aminobutyrate aminotransferase 7
axonal 6
diamine oxidase 6
Pseudomonas 6
insulin 5
choline acetyltransferase 5
somatostatin 5
glutamate receptor 5
DBA 5
Succinic semialdehyde dehydrogenase 5
Pol 5
acetylcholinesterase 5
substance P 5
CA1 5
ALA 4
prolactin 4
succinate-semialdehyde dehydrogenase 4
GAT-3 4
lactate dehydrogenase 4
rat) 4
adenylate cyclase 4
GAD1 4
citrate synthase 4
CA3 4
GABA-B receptor 4
CO2 4
LDH 4
2-oxoglutarate dehydrogenase 4
MRI 4
ornithine aminotransferase 4
parvalbumin 4
peroxidase 4
catalase 4
vesicular GABA transporter 3
GAT-2 3
MAO-B 3
chloride channel 3
dopa decarboxylase 3
ALDH5A1 3
isocitrate dehydrogenase 3
dopamine D2 receptor 3
arginine decarboxylase 3
ASP 3
gamma-amino butyric acid 3
polyamine oxidase 3
cholecystokinin 3
aldehyde dehydrogenase 3
SUCLG1 3
DAO 3
nitric oxide synthase 3
SSA 3
serum albumin 3
lipopolysaccharide 3
beta-endorphin 3
growth hormone 3
alpha-ketoglutarate dehydrogenase 3
GAD2 3
LHRH 3
cysteine sulfinic acid decarboxylase 2
superoxide dismutase 2
NADPH 2
neuropeptide Y 2
AMP 2
SPS 2
GAT2 2
GAT1 2
HER2 2
Glutamine synthetase 2
EOS 2
FADD 2
amine oxidase 2
adenosine A1 receptor 2
AChE 2
HOT 2
glial fibrillary acidic protein 2
She 2
TK2 2
5-HT receptor 2
Glutaminase 2
GRIN2A 2
NAD+ 2
Alanine aminotransferase 2
calmodulin 2
cage 2
ACTH 2
PCP 2
pyrroline-5-carboxylate synthetase 2
ACS 2
TRH 2
isocitric dehydrogenase 2
NR1 2
tryptophan hydroxylase 2
thymidylate synthase 2
MAO-A 2
hemoglobin 2
MDH1 2
adenosine triphosphatase 2
glucose-6-phosphate dehydrogenase 2
N-acetyltransferase 2
SUCLA2 2
MPV17 2
hole 2
oxoglutarate 2
calcium channel 2
A2BP1 2
follicle-stimulating hormone 2
glucagon 2
transcriptional regulator 2
ALDH6A1 2
SDH 2
histone deacetylase 2
nSMase2 2
serotonin N-acetyltransferase 2
hexokinase 2
catechol-O-methyltransferase 2
muscarinic receptor 2
ERG 2
PTGS2 2
FBXL4 1
SMA 1
cytochrome b 1
ABCA2 1
SRIF 1
dopamine D1 receptor 1
more...
Disease
epilepsy 75
GAD 59
fits 33
depression 18
complex partial seizures 11
cancer 9
cold 9
SCH 8
ischemia 8
schizophrenia 7
psychosis 5
autism 5
hypoglycemia 5
panic disorder 5
Alzheimer's disease 5
suicide 5
diabetes 5
anxiety disorders 5
DBA 5
encephalopathy 5
mental retardation 4
cocaine addiction 4
hepatocellular carcinoma 4
neuroblastoma 4
aggression 4
developmental delay 4
audiogenic seizure 4
mental retardation 4
Huntington's disease 4
migraine 4
status epilepticus 4
tardive dyskinesia 3
Lennox-Gastaut syndrome 3
alcoholism 3
catalepsy 3
temporal lobe epilepsy 3
parkinsonism 3
breast cancer 3
Succinic semialdehyde dehydrogenase deficiency 3
West 3
disinhibition 3
tuberous sclerosis 3
SPS 2
astrocytoma 2
tetanus 2
NAME 2
tumor growth 2
PCP 2
EOS 2
Hepatocellular carcinoma 2
iron deficiency 2
EOS 2
SPS 2
Autism 2
addiction 2
obesity 2
myelodysplastic syndrome 2
Lennox-Gastaut syndrome 2
fragile X syndrome 2
hyperprolactinemia 2
multiple sclerosis 2
sleep disorders 2
hypertension 2
brain tumor 1
PCC 1
Ellis-van Creveld syndrome 1
Infection 1
respiratory failure 1
listeriosis 1
Parkinson's disease 1
brain metastases 1
infertility 1
substance abuse 1
hyperglycemia 1
cocaine abuse 1
PME 1
catatonic schizophrenia 1
HCG 1
Nelson 1
glioma 1
Cerebellum 1
rickets 1
premenstrual dysphoric disorder 1
Pituitary 1
affective disorder 1
Rift Valley fever 1
amyotrophic lateral sclerosis 1
Venezuelan equine encephalitis 1
hyperphagia 1
trichotillomania 1
carcinoma 1
SCD 1
memory impairment 1
metastases 1
meninges 1
paranoid schizophrenia 1
emotional stress 1
African trypanosomiasis 1
anemia 1
herpes simplex 1
petit mal 1
PIC 1
lung carcinoma 1
tumor 1
duodenal ulcer 1
propionic acidemia 1
bipolar disorder 1
stroke 1
prematurity 1
drug withdrawal 1
MRS 1
infectious diseases 1
sickle cell disease 1
hepatic coma 1
sexual dysfunction 1
dementia 1
neoplastic process 1
PSA 1
meningitis 1
aminoaciduria 1
KRS 1
autoimmune disease 1
Disorder 1
leukemia 1
hyperosmolality 1
pheochromocytoma 1
Hyper-beta-alaninemia 1
Posterior 1
CSA 1
brain atrophy 1
panic attacks 1
uterine leiomyoma 1
renal cell carcinoma 1
moderate mental retardation 1
hyperglycinemia 1
diabetic hyperglycemia 1
Acute encephalopathy 1
OPA1 1
SDS 1
neurological disease 1
Wuchereria 1
apraxia 1
hypo-osmolality 1
ornithine transcarbamylase deficiency 1
cognitive impairment 1
movement disorder 1
febrile convulsions 1
anhedonia 1
coma 1
dysplasia 1
Inborn errors of metabolism 1
malaria 1
conjunctiva 1
sleep disturbances 1
ADHD 1
amnesia 1
PTD 1
drug addiction 1
cerebral ischemia 1
generalized seizure 1
more...
Symptom
seizures 105
hypotonia 8
ataxia 6
anesthesia 5
hypothermia 5
headache 5
lethargy 4
analgesia 4
pain 4
insomnia 3
sleepiness 3
starvation 2
myoclonus 2
anorexia 2
tremor 2
tinnitus 2
diarrhea 1
vertigo 1
distraction 1
impaired motor coordination 1
POA 1
partial seizure 1
tonic seizure 1
spasticity 1
tachypnea 1
constipation 1
Subjective tinnitus 1
agitation 1
dystonia 1
neuralgia 1
skin irritation 1
Psychiatric symptoms 1
bradykinesia 1
vomiting 1
clonus 1
ophthalmoplegia 1
eds 1
Drug
GVG 31
pyridoxal phosphate 14
Gabapentin 10
CSF 9
NADH 7
Sodium valproate 7
niacin 4
ALA 4
lysine 4
DPA 3
Apomorphine 3
citric acid 2
MAP 2
PCP 2
caffeine 2
Ethanol 2
Glutamic acid 1
Helium 1
Spectrum 1
OMP 1
Spectrum 1
NH3 1
Pyridoxal 1
TEL 1
Compound 9 1
vitamin E 1
Fengabine 1
Asn 1
Vitamin E 1
Estrogens 1
Abamectin 1
Sulpiride 1
Frontal 1
Stiripentol 1
FAD 1
Nephron 1
Gel 1
CDP 1
Activin 1
Isoniazid 1
Pyridoxal phosphate 1
Rufinamide 1
Quisqualate 1
Kainic acid 1
Pregabalin 1
Glucagon 1
ascorbate 1
balanced salt solution 1
Vitamin B 1
ROS 1
Propofol 1
L-tyrosine 1
Ethylenediamine 1
Phenytoin 1
Aminoguanidine 1
Pilocarpine 1
Ganaxolone 1
Leaf 1
Deferasirox 1
Enzyme
GABA transaminase 618
glutamate decarboxylase 105
succinic semialdehyde dehydrogenase 56
aspartate aminotransferase 21
alanine aminotransferase 18
glutamate dehydrogenase 17
glutamate dehydrogenase 17
glutamate dehydrogenase 17
monoamine oxidase 15
glutamine synthetase 12
tyrosine hydroxylase 11
glutaminase 11
ornithine decarboxylase 8
diamine oxidase 8
alpha-ketoglutarate dehydrogenase 7
peroxidase 6
succinate dehydrogenase 5
ornithine aminotransferase 5
choline acetyltransferase 5
acetylcholinesterase 5
adenylate cyclase 5
isocitrate dehydrogenase 5
lactate dehydrogenase 4
NO synthase 4
EC 1.2.1.16 4
catalase 4
citrate synthase 4
arginine decarboxylase 3
isocitrate dehydrogenase 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
ERK 3
ATPase 3
aldehyde dehydrogenase 3
arginine decarboxylase 3
glucose-6-phosphate dehydrogenase 3
aldehyde dehydrogenase 3
ACS 3
polyamine oxidase 3
S-adenosylmethionine decarboxylase 3
aldehyde dehydrogenase 3
reverse transcriptase 2
superoxide dismutase 2
thymidylate synthase 2
hydroxyacid-oxoacid transhydrogenase 2
hexokinase 2
deaminase 2
glutamic dehydrogenase 2
tryptophan hydroxylase 2
arylalkylamine N-acetyltransferase 2
SPS 2
DOPA decarboxylase 2
mitogen-activated protein kinase 2
PCP 2
branched-chain aminotransferase 2
N-acetyltransferase 2
pyruvate dehydrogenase 2
luciferase 2
CYP3A4 1
cyclohydrolase 1
CPT 1
acetylornithine aminotransferase 1
4CL 1
pyruvate carboxylase 1
propionyl-CoA carboxylase 1
RNA polymerase 1
alcohol dehydrogenase 1
acetyl-CoA synthetase 1
pyruvate kinase 1
adenylosuccinate lyase 1
dihydropyrimidine dehydrogenase 1
propionyl-CoA synthetase 1
EC 1.1.1.15 1
Xsc 1
NADPH-diaphorase 1
alanine racemase 1
fumarase 1
beta-galactosidase 1
cytochrome oxidase 1
aldehyde reductase 1
diaphorase 1
beta-alanine-pyruvate aminotransferase 1
nitrate reductase 1
nitrate reductase 1
AST 1
NADH dehydrogenase 1
aldose reductase 1
SCS 1
CPR 1
acid phosphatase 1
succinyl-CoA synthetase 1
phosphodiesterase 1
NADPH oxidase 1
nitrate reductase 1
pyruvate dehydrogenase 1
dihydropyrimidine dehydrogenase 1
NADPH oxidase 1
nitrate reductase 1
protein kinase C 1
pantothenate synthetase 1
desulfinase 1
arginase 1
RNase 1
serine hydroxymethyltransferase 1
glutathione reductase 1
ribonucleotide reductase 1
ascorbate oxidase 1
ribonucleotide reductase 1
nitrate reductase 1
alpha-aminoadipate aminotransferase 1
phosphatidylinositol 3-kinase 1
ascorbate peroxidase 1
pyruvate dehydrogenase 1
phosphoenolpyruvate carboxylase 1
caspase-3 1
BAT 1
renin 1
phosphoenolpyruvate carboxykinase 1
prolyl endopeptidase 1
phosphoenolpyruvate carboxykinase 1
nitrate reductase 1
D-3-aminoisobutyrate-pyruvate aminotransferase 1
propionyl-CoA carboxylase 1
glutathione peroxidase 1
RNase 1
ornithine transcarbamylase 1
phosphoinositide 3-kinase 1
enolase 1
sarcosine oxidase 1
aldehyde reductase 1
carbonic anhydrase 1
NOS 1
2-oxoglutarate decarboxylase 1
carnitine acetyltransferase 1
kallikrein 1
phosphoenolpyruvate carboxykinase 1
aromatic L-amino acid decarboxylase 1
malate dehydrogenase 1
proline dehydrogenase 1
complex I 1
aldehyde reductase 1
MPP 1
Compound
GABA 492
GABA 478
gamma-aminobutyric acid 232
glutamate 114
vinyl 106
Vigabatrin 70
sodium 58
2-oxoglutarate 56
Dec 48
glutamine 33
calcium 28
water 26
nitrogen 26
glucose 25
phosphate 24
alanine 22
beta-alanine 20
DNA 19
oxygen 18
glutamic acid 16
THIP 16
Clin 15
sulfate 15
butyric acid 14
butyric acid 14
butyric acid 14
ethanol 14
Valproic acid 14
ATP 13
Muscimol 12
tyrosine 11
NAD 11
potassium 11
noradrenaline 10
Glutamate 10
NAD 9
Gabaculine 9
PLP 9
nitric oxide 9
NMDA 9
Bicuculline 8
Asp 8
ornithine 8
ornithine 8
ornithine 8
gamma-hydroxybutyric acid 8
ornithine 8
acetate 8
ornithine 8
NADH 7
salt 7
urea 7
ammonia 7
Baclofen 7
proline 7
Diazepam 6
aldehyde 6
HBA 6
aldehyde 6
succinic acid 6
5-HT 6
arginine 6
succinic acid 5
DBA 5
ammonium 5
DBA 5
succinic acid 5
hydroxyindoleacetic acid 5
DBA 5
isonicotinic acid 5
hydrogen 5
succinic acid 5
5-hydroxytryptophan 5
succinic acid 5
CO2 5
lysine 5
hydrazine 5
2-aminoethylphosphonic acid 4
4-hydroxybenzaldehyde 4
4-hydroxybenzaldehyde 4
Phenelzine 4
4-hydroxybenzaldehyde 4
Phenelzine 4
CPP 4
4-hydroxybenzaldehyde 4
Lamotrigine 4
Valproic acid 4
aspartic acid 4
Cocaine 4
cAMP 4
4-hydroxybenzaldehyde 4
acetic acid 4
CPP 4
Phe 4
serine 3
L-leucine 3
aspartic acid 3
piperidine 3
AMPA 3
tryptophan 3
NH2 3
Glutamine 3
cobalt 3
2-pyrrolidinone 3
zinc 3
ETA 3
aminomethyl 3
Putrescine 3
tryptophan 3
pyridine 3
Mg2+ 3
Tiagabine 3
piperidine 3
iron 3
tryptophan 3
HCl 3
aspartic acid 3
aspartic acid 3
Picrotoxin 3
Picrotoxin 3
2-pyrrolidinone 3
leucine 3
tryptophan 3
Homotaurine 2
caffeine 2
MPTP 2
L-DOPA 2
Testosterone 2
galactose 2
Gly 2
3-MPA 2
DPA 2
prostaglandin E1 2
Flumazenil 2
DPA 2
NADP 2
benzaldehyde 2
pyrimidine 2
NADPH 2
Melatonin 2
Cardiol 2
Neuronal 2
hydroxyglutarate 2
2-pentenoic acid 2
DPA 2
Ethosuximide 2
DPA 2
PMP 2
iodine 2
INH 2
DPA 2
cGMP 2
isoxazole 2
Ketamine 2
asparagine 2
DBB 2
Progesterone 2
Methamphetamine 2
CNQX 2
ACh 2
more...