Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P80404 (
GABA transaminase
)
786
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The porphyrin precursor delta-aminolevulinic acid (delta-ALA) is a structural analogue of the putative amino acid neurotransmitter, gamma-aminobutyric acid (GABA). This study has demonstrated that delta-ALA has no effect on glutamate decarboxylase activity and only a small inhibitory effect of
GABA aminotransferase
activity. This would suggest that if accumulation of delta-ALA is related to development of the acute attack of
porphyria
, it is not via an effect on GABA synthesis and metabolism.
...
PMID:The effect of delta-aminolevulinic acid on the synthesis and metabolism of GABA in rabbit brain homogenates. 736 97
