Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P62988 (
Ubiquitin
)
4,326
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Ubiquitin
4326
ubiquitin
2625
proteasome
1087
Mol
672
Sep
246
ubiquitin ligase
243
E3 ubiquitin ligase
190
ATP
158
deubiquitinating enzyme
141
NMR
134
Proteasome
134
SUMO
125
p53
121
endoplasmic reticulum
103
fused
94
SCF
88
polypeptide
85
proteasome inhibitor
84
ubiquitin-conjugating enzyme
82
interferon
76
p62
76
peptidase
75
ATPase
72
diubiquitin
66
Ubc13
63
cytokine
59
ubiquitin-specific protease
59
NEMO
57
cullin
56
A20
52
BRCA1
51
TNF
50
histone
50
TRAF6
46
IKK
45
CYLD
44
ubiquitin-like protein
44
Skp1
43
interacting protein
42
F-box protein
42
p97
41
LC3
41
PDB
41
NEDD8
41
RIG-I
40
proliferating cell nuclear antigen
39
PHD
38
Parkin
37
zinc finger
35
E2 ubiquitin-conjugating enzyme
35
APC
33
Rpn10
33
tumor necrosis factor
33
GST
32
cyclin
31
ISG15
31
USP7
30
IFN
30
p21
28
histone H2A
28
TAK1
28
insulin
27
catenin
27
Cdc48
26
SDS
26
amyloid precursor protein
26
caspase-3
25
adaptor protein
25
axonal
25
USP5
25
VCP
25
ubiquitin conjugating enzyme
25
AAA
25
Mdm2
24
JNK
24
UBC
24
K27
23
ataxin-3
23
type I interferon
23
IkappaB kinase
22
more...
Disease
cancer
432
tumor
278
Alzheimer's disease
109
tumorigenesis
105
Parkinson's disease
80
virus infection
64
dementia
61
amyotrophic lateral sclerosis
54
breast cancer
52
tumor progression
46
hepatocellular carcinoma
42
tumor growth
37
CYLD
35
APC
34
leukemia
33
ischemia
29
carcinoma
28
cold
27
motor neuron disease
27
carcinogenesis
26
SDS
26
multiple myeloma
25
muscular atrophy
25
AAA
25
abdominal aortic aneurysm
25
lung cancer
24
colorectal cancer
24
diabetes
24
adenocarcinoma
22
prostate cancer
21
gastric cancer
18
immunodeficiency
18
Huntington's disease
18
myopathy
16
metastases
16
ovarian cancer
16
non-small cell lung cancer
16
influenza
15
sepsis
15
HIV
15
pruritus
14
parkinsonism
14
tuberculosis
14
SARS
14
Legionella
13
Epstein
13
infertility
13
heart failure
13
melanoma
13
squamous cell carcinoma
13
sepsis
13
herpes simplex
12
liver disease
12
depression
12
glioma
12
PDB
12
Pick's disease
12
ATM
12
Mycobacterium
12
hypertension
11
plaque
11
Dementia with Lewy bodies
11
PML
11
acute promyelocytic leukemia
11
pancreatic cancer
10
MCF
10
colon cancer
10
progressive supranuclear palsy
10
anemia
10
hepatitis B
9
neuroblastoma
9
Angelman syndrome
9
bacterial infection
9
lymphoma
9
Kaposi's sarcoma
9
male infertility
8
Hippel
8
cytomegalovirus
8
B-cell lymphoma
8
glioblastoma
8
more...
Symptom
starvation
31
ataxia
16
weakness
9
collapse
7
seizures
6
respiratory distress
5
cachexia
5
diarrhea
4
tremor
4
pain
4
myoclonus
2
dysarthria
2
hypothermia
2
bradykinesia
2
fatigue
2
hypotonia
2
pallor
1
irregular bleeding
1
erythema
1
cerebellar ataxia
1
apathy
1
despair
1
twitching
1
hepatomegaly
1
sleepiness
1
anorexia
1
anesthesia
1
dystonia
1
Flaccid dysarthria
1
splenomegaly
1
loss of taste
1
acute stress
1
exhaustion
1
spasticity
1
memory loss
1
male subfertility
1
agitation
1
colic
1
acidity
1
Drug
lysine
427
Parkin
37
Parkin
37
ROS
16
AMC
12
Bortezomib
10
Retinoic acid
6
GEO
4
Asn
4
Monit
4
Biopolymers
4
Adriamycin
3
IFN-gamma
3
Gel
3
CSF
3
Glutathione
3
TAT
3
Cardiovasc
3
Kenyan
3
ACT
3
NADH
3
ROC
3
Fraction
3
EE2
2
IFN-beta
2
L-tyrosine
2
MAP
2
Ethanol
2
IL-2
2
Leaf
2
Amiloride
2
Amiloride
2
ascorbate
2
RFP
2
Gleevec
1
CTC
1
Paraffin
1
Forskolin
1
ATV
1
Glycerol
1
MDM
1
citric acid
1
caffeine
1
Maltose
1
ADR
1
p75
1
BLM
1
ABC
1
HCG
1
Lenalidomide
1
Singular
1
Heme
1
DM1
1
Glide
1
TAK
1
Ketoconazole
1
Nitric Oxide
1
Gefitinib
1
Fluconazole
1
RBT
1
CTC
1
Itraconazole
1
BH4
1
Capsicum
1
Dihydro
1
Alliance
1
Gelatin
1
TAC
1
Dermatol
1
PCP
1
balanced salt solution
1
Angiotensin II
1
NVP
1
Asthma
1
ADM
1
Xanthium
1
Fluorescein
1
Papain
1
Enzyme
proteasome
1094
IKK
82
protein kinase
80
ATPase
74
mitogen-activated protein kinase
66
ubiquitin-protein ligase
55
isopeptidase
51
PHD
38
glutathione S-transferase
38
ERK
37
APC
35
trypsin
32
luciferase
26
papain
24
caspase-3
22
lysozyme
20
glyceraldehyde-3-phosphate dehydrogenase
20
protein kinase C
18
calcineurin
16
glyceraldehyde-3-phosphate dehydrogenase
15
AMP-activated protein kinase
14
ACS
13
beta-glucuronidase
12
cdc2
12
superoxide dismutase
12
caspase-8
12
AMPK
11
glyceraldehyde-3-phosphate dehydrogenase
11
PARP
11
glyceraldehyde-3-phosphate dehydrogenase
11
glyceraldehyde-3-phosphate dehydrogenase
11
RNA polymerase
11
cathepsin B
10
AMPK
10
protein phosphatase 2A
10
ornithine decarboxylase
9
catalase
9
MEK
8
focal adhesion kinase
8
peroxidase
8
beta-galactosidase
8
cathepsin D
7
RNase
7
tyrosine hydroxylase
7
polo-like kinase 1
6
phosphatidylinositol 3-kinase
6
MEKK1
6
chymotrypsin
5
dihydrofolate reductase
5
carbonic anhydrase
5
GSK
5
topoisomerase
4
caspase-1
4
endonuclease
4
lipoxygenase
4
conjugase
4
RNase
4
carboxypeptidase Y
4
phosphoglycerate kinase
4
ubiquityl-calmodulin synthetase
4
DNA polymerase
4
complex I
3
3C protease
3
NADPH oxidase
3
aspartate aminotransferase
3
reverse transcriptase
3
TAT
3
phosphoinositide 3-kinase
3
NADPH oxidase
3
Protein 2
3
phospholipase C
3
CEP
3
invertase
3
demethylase
3
histone acetyltransferase
3
phosphodiesterase
3
caspase-9
3
alkaline phosphatase
3
peroxiredoxin
3
topoisomerase
3
more...
Compound
Ubiquitin
2654
lysine
593
DNA
552
Dec
309
ATP
158
cysteine
104
tyrosine
53
oxygen
50
TNF
50
zinc
48
serine
46
arginine
46
Clin
43
alanine
42
Gly
42
methionine
41
His
40
water
40
leucine
37
salt
36
threonine
36
hydrogen
34
calcium
31
Phe
26
glucose
26
SDS
26
sodium
25
AAA
25
Cbl
23
CUE
22
aldehyde
20
aldehyde
20
Asp
19
phosphate
19
Ile
19
NH2
17
sulfate
17
glutamine
16
cAMP
16
AMP
16
glutamate
16
CHIP
15
ADP
15
cadmium
15
Cardiol
15
acetate
15
iron
14
ADP
14
ADP
14
urea
13
ACS
13
ACS
13
proline
13
retinoic acid
12
MDA
12
TOF
12
PEG
12
ethanol
12
tryptophan
11
nitrogen
11
MTT
11
nitric oxide
11
PDB
9
GSH
9
potassium
9
GSH
9
Neuronal
9
salicylic acid
9
H2O2
8
methanol
8
tryptophan
8
DPA
8
ABA
7
TNM
7
copper
7
boron
7
cGMP
7
ABA
7
silver
7
PEG
7
more...