Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P62988 (Ubiquitin)
4,326 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Ubiquitin 4326
ubiquitin 2625
proteasome 1087
Mol 672
Sep 246
ubiquitin ligase 243
E3 ubiquitin ligase 190
ATP 158
deubiquitinating enzyme 141
NMR 134
Proteasome 134
SUMO 125
p53 121
endoplasmic reticulum 103
fused 94
SCF 88
polypeptide 85
proteasome inhibitor 84
ubiquitin-conjugating enzyme 82
interferon 76
p62 76
peptidase 75
ATPase 72
diubiquitin 66
Ubc13 63
cytokine 59
ubiquitin-specific protease 59
NEMO 57
cullin 56
A20 52
BRCA1 51
TNF 50
histone 50
TRAF6 46
IKK 45
CYLD 44
ubiquitin-like protein 44
Skp1 43
interacting protein 42
F-box protein 42
p97 41
LC3 41
PDB 41
NEDD8 41
RIG-I 40
proliferating cell nuclear antigen 39
PHD 38
Parkin 37
zinc finger 35
E2 ubiquitin-conjugating enzyme 35
APC 33
Rpn10 33
tumor necrosis factor 33
GST 32
cyclin 31
ISG15 31
USP7 30
IFN 30
p21 28
histone H2A 28
TAK1 28
insulin 27
catenin 27
Cdc48 26
SDS 26
amyloid precursor protein 26
caspase-3 25
adaptor protein 25
axonal 25
USP5 25
VCP 25
ubiquitin conjugating enzyme 25
AAA 25
Mdm2 24
JNK 24
UBC 24
K27 23
ataxin-3 23
type I interferon 23
IkappaB kinase 22
more...
Disease
cancer 432
tumor 278
Alzheimer's disease 109
tumorigenesis 105
Parkinson's disease 80
virus infection 64
dementia 61
amyotrophic lateral sclerosis 54
breast cancer 52
tumor progression 46
hepatocellular carcinoma 42
tumor growth 37
CYLD 35
APC 34
leukemia 33
ischemia 29
carcinoma 28
cold 27
motor neuron disease 27
carcinogenesis 26
SDS 26
multiple myeloma 25
muscular atrophy 25
AAA 25
abdominal aortic aneurysm 25
lung cancer 24
colorectal cancer 24
diabetes 24
adenocarcinoma 22
prostate cancer 21
gastric cancer 18
immunodeficiency 18
Huntington's disease 18
myopathy 16
metastases 16
ovarian cancer 16
non-small cell lung cancer 16
influenza 15
sepsis 15
HIV 15
pruritus 14
parkinsonism 14
tuberculosis 14
SARS 14
Legionella 13
Epstein 13
infertility 13
heart failure 13
melanoma 13
squamous cell carcinoma 13
sepsis 13
herpes simplex 12
liver disease 12
depression 12
glioma 12
PDB 12
Pick's disease 12
ATM 12
Mycobacterium 12
hypertension 11
plaque 11
Dementia with Lewy bodies 11
PML 11
acute promyelocytic leukemia 11
pancreatic cancer 10
MCF 10
colon cancer 10
progressive supranuclear palsy 10
anemia 10
hepatitis B 9
neuroblastoma 9
Angelman syndrome 9
bacterial infection 9
lymphoma 9
Kaposi's sarcoma 9
male infertility 8
Hippel 8
cytomegalovirus 8
B-cell lymphoma 8
glioblastoma 8
more...
Symptom
starvation 31
ataxia 16
weakness 9
collapse 7
seizures 6
respiratory distress 5
cachexia 5
diarrhea 4
tremor 4
pain 4
myoclonus 2
dysarthria 2
hypothermia 2
bradykinesia 2
fatigue 2
hypotonia 2
pallor 1
irregular bleeding 1
erythema 1
cerebellar ataxia 1
apathy 1
despair 1
twitching 1
hepatomegaly 1
sleepiness 1
anorexia 1
anesthesia 1
dystonia 1
Flaccid dysarthria 1
splenomegaly 1
loss of taste 1
acute stress 1
exhaustion 1
spasticity 1
memory loss 1
male subfertility 1
agitation 1
colic 1
acidity 1
Drug
lysine 427
Parkin 37
Parkin 37
ROS 16
AMC 12
Bortezomib 10
Retinoic acid 6
GEO 4
Asn 4
Monit 4
Biopolymers 4
Adriamycin 3
IFN-gamma 3
Gel 3
CSF 3
Glutathione 3
TAT 3
Cardiovasc 3
Kenyan 3
ACT 3
NADH 3
ROC 3
Fraction 3
EE2 2
IFN-beta 2
L-tyrosine 2
MAP 2
Ethanol 2
IL-2 2
Leaf 2
Amiloride 2
Amiloride 2
ascorbate 2
RFP 2
Gleevec 1
CTC 1
Paraffin 1
Forskolin 1
ATV 1
Glycerol 1
MDM 1
citric acid 1
caffeine 1
Maltose 1
ADR 1
p75 1
BLM 1
ABC 1
HCG 1
Lenalidomide 1
Singular 1
Heme 1
DM1 1
Glide 1
TAK 1
Ketoconazole 1
Nitric Oxide 1
Gefitinib 1
Fluconazole 1
RBT 1
CTC 1
Itraconazole 1
BH4 1
Capsicum 1
Dihydro 1
Alliance 1
Gelatin 1
TAC 1
Dermatol 1
PCP 1
balanced salt solution 1
Angiotensin II 1
NVP 1
Asthma 1
ADM 1
Xanthium 1
Fluorescein 1
Papain 1
Enzyme
proteasome 1094
IKK 82
protein kinase 80
ATPase 74
mitogen-activated protein kinase 66
ubiquitin-protein ligase 55
isopeptidase 51
PHD 38
glutathione S-transferase 38
ERK 37
APC 35
trypsin 32
luciferase 26
papain 24
caspase-3 22
lysozyme 20
glyceraldehyde-3-phosphate dehydrogenase 20
protein kinase C 18
calcineurin 16
glyceraldehyde-3-phosphate dehydrogenase 15
AMP-activated protein kinase 14
ACS 13
beta-glucuronidase 12
cdc2 12
superoxide dismutase 12
caspase-8 12
AMPK 11
glyceraldehyde-3-phosphate dehydrogenase 11
PARP 11
glyceraldehyde-3-phosphate dehydrogenase 11
glyceraldehyde-3-phosphate dehydrogenase 11
RNA polymerase 11
cathepsin B 10
AMPK 10
protein phosphatase 2A 10
ornithine decarboxylase 9
catalase 9
MEK 8
focal adhesion kinase 8
peroxidase 8
beta-galactosidase 8
cathepsin D 7
RNase 7
tyrosine hydroxylase 7
polo-like kinase 1 6
phosphatidylinositol 3-kinase 6
MEKK1 6
chymotrypsin 5
dihydrofolate reductase 5
carbonic anhydrase 5
GSK 5
topoisomerase 4
caspase-1 4
endonuclease 4
lipoxygenase 4
conjugase 4
RNase 4
carboxypeptidase Y 4
phosphoglycerate kinase 4
ubiquityl-calmodulin synthetase 4
DNA polymerase 4
complex I 3
3C protease 3
NADPH oxidase 3
aspartate aminotransferase 3
reverse transcriptase 3
TAT 3
phosphoinositide 3-kinase 3
NADPH oxidase 3
Protein 2 3
phospholipase C 3
CEP 3
invertase 3
demethylase 3
histone acetyltransferase 3
phosphodiesterase 3
caspase-9 3
alkaline phosphatase 3
peroxiredoxin 3
topoisomerase 3
more...
Compound
Ubiquitin 2654
lysine 593
DNA 552
Dec 309
ATP 158
cysteine 104
tyrosine 53
oxygen 50
TNF 50
zinc 48
serine 46
arginine 46
Clin 43
alanine 42
Gly 42
methionine 41
His 40
water 40
leucine 37
salt 36
threonine 36
hydrogen 34
calcium 31
Phe 26
glucose 26
SDS 26
sodium 25
AAA 25
Cbl 23
CUE 22
aldehyde 20
aldehyde 20
Asp 19
phosphate 19
Ile 19
NH2 17
sulfate 17
glutamine 16
cAMP 16
AMP 16
glutamate 16
CHIP 15
ADP 15
cadmium 15
Cardiol 15
acetate 15
iron 14
ADP 14
ADP 14
urea 13
ACS 13
ACS 13
proline 13
retinoic acid 12
MDA 12
TOF 12
PEG 12
ethanol 12
tryptophan 11
nitrogen 11
MTT 11
nitric oxide 11
PDB 9
GSH 9
potassium 9
GSH 9
Neuronal 9
salicylic acid 9
H2O2 8
methanol 8
tryptophan 8
DPA 8
ABA 7
TNM 7
copper 7
boron 7
cGMP 7
ABA 7
silver 7
PEG 7
more...