Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P62988 (Ubiquitin)
4,326 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Ubiquitin 4326
ubiquitin 2625
proteasome 1087
Mol 672
Sep 246
ubiquitin ligase 243
E3 ubiquitin ligase 190
ATP 158
deubiquitinating enzyme 141
Proteasome 134
NMR 134
SUMO 125
p53 121
endoplasmic reticulum 103
fused 94
SCF 88
polypeptide 85
proteasome inhibitor 84
ubiquitin-conjugating enzyme 82
p62 76
interferon 76
peptidase 75
ATPase 72
diubiquitin 66
Ubc13 63
cytokine 59
ubiquitin-specific protease 59
NEMO 57
cullin 56
A20 52
BRCA1 51
TNF 50
histone 50
TRAF6 46
IKK 45
CYLD 44
ubiquitin-like protein 44
Skp1 43
F-box protein 42
interacting protein 42
more...
Disease
cancer 432
tumor 278
Alzheimer's disease 109
tumorigenesis 105
Parkinson's disease 80
virus infection 64
dementia 61
amyotrophic lateral sclerosis 54
breast cancer 52
tumor progression 46
hepatocellular carcinoma 42
tumor growth 37
CYLD 35
APC 34
leukemia 33
ischemia 29
carcinoma 28
cold 27
motor neuron disease 27
SDS 26
carcinogenesis 26
abdominal aortic aneurysm 25
muscular atrophy 25
multiple myeloma 25
AAA 25
lung cancer 24
diabetes 24
colorectal cancer 24
adenocarcinoma 22
prostate cancer 21
immunodeficiency 18
gastric cancer 18
Huntington's disease 18
non-small cell lung cancer 16
myopathy 16
metastases 16
ovarian cancer 16
sepsis 15
influenza 15
HIV 15
more...
Symptom
starvation 31
ataxia 16
weakness 9
collapse 7
seizures 6
respiratory distress 5
cachexia 5
diarrhea 4
tremor 4
pain 4
myoclonus 2
dysarthria 2
hypothermia 2
bradykinesia 2
fatigue 2
hypotonia 2
pallor 1
irregular bleeding 1
erythema 1
cerebellar ataxia 1
apathy 1
despair 1
twitching 1
hepatomegaly 1
sleepiness 1
anorexia 1
anesthesia 1
dystonia 1
Flaccid dysarthria 1
splenomegaly 1
loss of taste 1
acute stress 1
exhaustion 1
spasticity 1
memory loss 1
male subfertility 1
agitation 1
colic 1
acidity 1
Drug
lysine 427
Parkin 37
Parkin 37
ROS 16
AMC 12
Bortezomib 10
Retinoic acid 6
Asn 4
Biopolymers 4
GEO 4
Monit 4
Kenyan 3
Glutathione 3
CSF 3
Fraction 3
NADH 3
ROC 3
Adriamycin 3
IFN-gamma 3
Gel 3
Cardiovasc 3
TAT 3
ACT 3
L-tyrosine 2
ascorbate 2
IFN-beta 2
MAP 2
Ethanol 2
EE2 2
Amiloride 2
IL-2 2
Amiloride 2
Leaf 2
RFP 2
BH4 1
CTC 1
Dihydro 1
Forskolin 1
Dermatol 1
citric acid 1
more...
Enzyme
proteasome 1094
IKK 82
protein kinase 80
ATPase 74
mitogen-activated protein kinase 66
ubiquitin-protein ligase 55
isopeptidase 51
glutathione S-transferase 38
PHD 38
ERK 37
APC 35
trypsin 32
luciferase 26
papain 24
caspase-3 22
glyceraldehyde-3-phosphate dehydrogenase 20
lysozyme 20
protein kinase C 18
calcineurin 16
glyceraldehyde-3-phosphate dehydrogenase 15
AMP-activated protein kinase 14
ACS 13
beta-glucuronidase 12
caspase-8 12
superoxide dismutase 12
cdc2 12
RNA polymerase 11
glyceraldehyde-3-phosphate dehydrogenase 11
AMPK 11
glyceraldehyde-3-phosphate dehydrogenase 11
glyceraldehyde-3-phosphate dehydrogenase 11
PARP 11
protein phosphatase 2A 10
AMPK 10
cathepsin B 10
ornithine decarboxylase 9
catalase 9
peroxidase 8
focal adhesion kinase 8
beta-galactosidase 8
more...
Compound
Ubiquitin 2654
lysine 593
DNA 552
Dec 309
ATP 158
cysteine 104
tyrosine 53
TNF 50
oxygen 50
zinc 48
serine 46
arginine 46
Clin 43
Gly 42
alanine 42
methionine 41
His 40
water 40
leucine 37
threonine 36
salt 36
hydrogen 34
calcium 31
glucose 26
Phe 26
SDS 26
sodium 25
AAA 25
Cbl 23
CUE 22
aldehyde 20
aldehyde 20
phosphate 19
Asp 19
Ile 19
sulfate 17
NH2 17
cAMP 16
glutamate 16
glutamine 16
more...