Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P62988 (
Ubiquitin
)
4,326
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Ubiquitin
4326
ubiquitin
2625
proteasome
1087
Mol
672
Sep
246
ubiquitin ligase
243
E3 ubiquitin ligase
190
ATP
158
deubiquitinating enzyme
141
Proteasome
134
NMR
134
SUMO
125
p53
121
endoplasmic reticulum
103
fused
94
SCF
88
polypeptide
85
proteasome inhibitor
84
ubiquitin-conjugating enzyme
82
p62
76
interferon
76
peptidase
75
ATPase
72
diubiquitin
66
Ubc13
63
cytokine
59
ubiquitin-specific protease
59
NEMO
57
cullin
56
A20
52
BRCA1
51
TNF
50
histone
50
TRAF6
46
IKK
45
CYLD
44
ubiquitin-like protein
44
Skp1
43
F-box protein
42
interacting protein
42
more...
Disease
cancer
432
tumor
278
Alzheimer's disease
109
tumorigenesis
105
Parkinson's disease
80
virus infection
64
dementia
61
amyotrophic lateral sclerosis
54
breast cancer
52
tumor progression
46
hepatocellular carcinoma
42
tumor growth
37
CYLD
35
APC
34
leukemia
33
ischemia
29
carcinoma
28
cold
27
motor neuron disease
27
SDS
26
carcinogenesis
26
abdominal aortic aneurysm
25
muscular atrophy
25
multiple myeloma
25
AAA
25
lung cancer
24
diabetes
24
colorectal cancer
24
adenocarcinoma
22
prostate cancer
21
immunodeficiency
18
gastric cancer
18
Huntington's disease
18
non-small cell lung cancer
16
myopathy
16
metastases
16
ovarian cancer
16
sepsis
15
influenza
15
HIV
15
more...
Symptom
starvation
31
ataxia
16
weakness
9
collapse
7
seizures
6
respiratory distress
5
cachexia
5
diarrhea
4
tremor
4
pain
4
myoclonus
2
dysarthria
2
hypothermia
2
bradykinesia
2
fatigue
2
hypotonia
2
pallor
1
irregular bleeding
1
erythema
1
cerebellar ataxia
1
apathy
1
despair
1
twitching
1
hepatomegaly
1
sleepiness
1
anorexia
1
anesthesia
1
dystonia
1
Flaccid dysarthria
1
splenomegaly
1
loss of taste
1
acute stress
1
exhaustion
1
spasticity
1
memory loss
1
male subfertility
1
agitation
1
colic
1
acidity
1
Drug
lysine
427
Parkin
37
Parkin
37
ROS
16
AMC
12
Bortezomib
10
Retinoic acid
6
Asn
4
Biopolymers
4
GEO
4
Monit
4
Kenyan
3
Glutathione
3
CSF
3
Fraction
3
NADH
3
ROC
3
Adriamycin
3
IFN-gamma
3
Gel
3
Cardiovasc
3
TAT
3
ACT
3
L-tyrosine
2
ascorbate
2
IFN-beta
2
MAP
2
Ethanol
2
EE2
2
Amiloride
2
IL-2
2
Amiloride
2
Leaf
2
RFP
2
BH4
1
CTC
1
Dihydro
1
Forskolin
1
Dermatol
1
citric acid
1
more...
Enzyme
proteasome
1094
IKK
82
protein kinase
80
ATPase
74
mitogen-activated protein kinase
66
ubiquitin-protein ligase
55
isopeptidase
51
glutathione S-transferase
38
PHD
38
ERK
37
APC
35
trypsin
32
luciferase
26
papain
24
caspase-3
22
glyceraldehyde-3-phosphate dehydrogenase
20
lysozyme
20
protein kinase C
18
calcineurin
16
glyceraldehyde-3-phosphate dehydrogenase
15
AMP-activated protein kinase
14
ACS
13
beta-glucuronidase
12
caspase-8
12
superoxide dismutase
12
cdc2
12
RNA polymerase
11
glyceraldehyde-3-phosphate dehydrogenase
11
AMPK
11
glyceraldehyde-3-phosphate dehydrogenase
11
glyceraldehyde-3-phosphate dehydrogenase
11
PARP
11
protein phosphatase 2A
10
AMPK
10
cathepsin B
10
ornithine decarboxylase
9
catalase
9
peroxidase
8
focal adhesion kinase
8
beta-galactosidase
8
more...
Compound
Ubiquitin
2654
lysine
593
DNA
552
Dec
309
ATP
158
cysteine
104
tyrosine
53
TNF
50
oxygen
50
zinc
48
serine
46
arginine
46
Clin
43
Gly
42
alanine
42
methionine
41
His
40
water
40
leucine
37
threonine
36
salt
36
hydrogen
34
calcium
31
glucose
26
Phe
26
SDS
26
sodium
25
AAA
25
Cbl
23
CUE
22
aldehyde
20
aldehyde
20
phosphate
19
Asp
19
Ile
19
sulfate
17
NH2
17
cAMP
16
glutamate
16
glutamine
16
more...