Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P62988 (Ubiquitin)
 4,326 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
OTUD3 protein 12.8
UBCH6 12.8
LINCR 12.8
cyclin-related protein FAM58A 12.8
NCUBE1 12.8
CYP51A1 protein 12.8
signal recognition particle receptor beta subunit 12.8
NCUBE2 12.8
Ubiquitin carboxyl-terminal hydrolase 37 12.8
Ubiquitin 12.8
TRIM6 protein 12.8
E3a ligase 12.8
UBFD1 12.8
UBL5 protein 12.3
STAM-binding protein-like 1 12.2
USP41 11.8
Tripartite motif-containing protein 45 11.8
Muscle, skeletal, receptor tyrosine kinase 11.8
TGS2 11.8
zinc finger, RAN-binding domain containing 3 11.8
dendritic cell-derived ubiquitin-like protein 11.8
ubiquitin carboxyl-terminal hydrolase L5 11.8
target of myb1 11.8
TBC1 domain family member 9 11.8
FAM63A 11.8
RNA HELICASE 11.8
TRAC-1 11.8
tripartite motif family-like 1 11.8
nuclear protein localization 4 11.8
ubiquitin-conjugating enzyme 16 11.8
TMED1 11.8
TNFAIP3 interacting protein 2 11.8
KIF24 11.8
RNFT1 11.8
60S ribosomal protein L23 11.8
UBE2E1 11.7
diubiquitin 11.6
UBIN 11.5
NZF1 11.5
USP10 protein 11.5
Riplet 11.3
Ubiquitin B 11.3
F-box and leucine-rich repeat protein 4 11.3
C19orf62 11.3
ASB10 11.3
Ribosomal protein S9 11.3
ring finger protein 126 11.3
RING finger protein 208 11.3
TEX27 11.3
THAP5 11.3
OTUD2 11.3
ZCCHC3 11.3
UBE2Q1 protein 11.3
RC3H2 11.3
FAM105B 11.3
UBE2S 11.2
SMAX2 11.1
DSK2 11.1
UBXN1 11.1
MOV34 11.0
UBP41 11.0
C1orf124 11.0
UBE2W 11.0
UBE2Q1 11.0
Ubc13 10.9
DUB1 10.8
SLC25A39 10.8
RNF166 10.8
USP54 10.8
OTUD3 10.8
NEDL2 10.8
lysozyme precursor 10.8
USP28 protein 10.8
FBXO21 10.8
APPBP1 10.8
UbcH2 10.8
presenilin-binding protein 10.8
UBC4/5 10.8
ubiquitin specific protease 17 10.8
RALGPS1 10.8
zinc finger protein 638 10.8
ZNF216 10.8
UBC protein 10.8
NEDD8-conjugating enzyme 10.8
HECTD1 protein 10.8
ZUFSP 10.8
HECTD3 10.8
ring finger protein 3 10.8
UbcH6 10.8
Dsk2 10.8
UBE2V1 10.7
UBE2D1 10.7
Ufm1 10.7
MARCH7 10.7
ZRANB1 10.7
USP5 10.6
USP4 10.6
AMSH 10.6
TUBE 10.6
CARD2 10.5
N4BP1 10.5
USP25 10.5
UbA52 10.5
PJA2 10.5
ubiquitin specific peptidase 16 10.5
PSMA8 10.5
UbcM2 10.5
TXNDC8 10.5
RALGPS2 10.5
WDR20 10.5
ING3 protein 10.5
MOSC1 10.5
PELI3 10.5
HSPA5 protein 10.5
ubiquitin fusion protein 10.5
POH1 10.5
TRIM6 10.4
USP11 10.4
Rpn10 10.4
Elongation factor 1-alpha 10.4
UBE2R2 10.4
USP37 10.4
UBA3 10.4
USP15 10.3
USP19 10.3
Uba5 10.3
hHR23A 10.3
Werner helicase-interacting protein 1 10.3
Ribosomal protein L18 10.3
Lysophosphatidic acid receptor 1 10.3
RBM26 10.3
CRIP3 10.3
otubain 1 10.3
URM1 10.3
ASCC2 10.3
Ufc1 10.3
Uba80 10.3
TMEM33 10.3
UBC3 10.3
PNUTL2 10.3
UFD2 10.3
HOIL-1 10.3
Ubiquitin-activating enzyme 10.3
Ozz 10.3
erasin 10.3
Sharpin 10.2
deubiquitinating enzyme 10.2
USP14 10.2
UCH37 10.2
UBD 10.1
ABIN2 10.1
E2-F1 10.1
E2 ubiquitin-conjugating enzyme 10.1
UBB 10.1
RPS27A 10.1
SHARPIN 10.1
TRIM40 10.0
Tomosyn-1 10.0
ubiquitin-conjugating enzyme E2A 10.0
ubiquitin-conjugating enzyme E2S 10.0
more...
Disease
SMAX2 11.8
Amyotrophic lateral sclerosis with dementia 11.3
SCA23 9.8
CYLD 9.6
PARK5 9.5
Congenital Myasthenic Syndromes 9.4
PARK13 9.3
LGMD2H 9.0
PARK4 8.8
PARK3 8.8
TORCH syndrome 8.4
ALS8 8.3
EPM2B 8.1
FTD-ALS 8.0
Semantic dementia 7.8
Avian infectious bronchitis 7.5
PARK1 7.5
Progressive Aphasia 7.5
transcortical aphasia 7.4
EBSS 7.3
PARK6 7.2
HRD 6.9
Neovascular age-related macular degeneration 6.8
FTLD 6.8
Pick's disease 6.8
Johanson-Blizzard syndrome 6.7
Transient ischemia 6.6
cerebral degeneration 6.6
PARK8 6.6
Cortical dysplasia 6.5
ARTS 6.5
Congenital muscular dystrophy 6.5
environmental carcinogenesis 6.4
VISA 6.4
PARK7 6.4
FANCI 6.3
abulia 6.2
PARK2 6.2
Kufs' disease 6.1
motor neuron disease 6.1
KRS 6.1
RHS 6.0
Angelman syndrome 6.0
AAA 5.9
Danon disease 5.9
PanIN 5.9
Werdnig-Hoffmann disease 5.8
Neurodegenerative Disorders 5.7
uterine carcinosarcoma 5.7
Carrion 5.6
X-linked hyper-IgM syndrome 5.6
Machado-Joseph disease 5.6
Dementia with Lewy bodies 5.6
valvulitis 5.6
MPS IIIA 5.6
Trichinella infection 5.5
multiple disorders 5.5
lymphoblastoma 5.5
CCA1 5.5
IBR 5.4
EDS1 5.4
incontinentia pigmenti 5.4
XP-A 5.4
anomia 5.4
DBA2 5.3
kidney hypertrophy 5.2
occupational lung disease 5.2
primary lateral sclerosis 5.1
LBD 5.1
ovarian neoplasm 5.1
ISM 5.0
Rosenthal 4.9
agraphia 4.9
Spinocerebellar ataxia 4.8
FHA 4.8
velocardiofacial syndrome 4.8
Tauopathies 4.8
LAD2 4.8
alexia 4.8
progressive muscular atrophy 4.7
familial disorder 4.7
CEP 4.6
testicular dysfunction 4.6
ectodermal dysplasia 4.6
APC 4.6
Cancer cachexia 4.6
dyscalculia 4.6
muscular atrophy 4.5
presenile dementia 4.5
LIN 4.4
progressive supranuclear palsy 4.4
osteoarthropathy 4.4
abdominal aortic aneurysm 4.4
amyotrophic lateral sclerosis 4.4
Alexander disease 4.4
Bielschowsky 4.3
trichothiodystrophy 4.3
organic brain syndrome 4.3
SCA1 4.3
nasal allergy 4.3
PML 4.3
RPC 4.2
Multiple system atrophy 4.1
pellagra 4.1
RP11 4.1
SCP 4.0
Alcoholic liver disease 4.0
MDM 4.0
Atrophic 4.0
alcoholic hepatitis 3.9
Frontotemporal dementia 3.9
HRS 3.9
olivopontocerebellar atrophy 3.9
Persistent infection 3.9
SM1 3.9
lysosomal storage disease 3.9
ARVD 3.9
western equine encephalomyelitis 3.8
CSB 3.8
inflammatory joint disease 3.8
CSB 3.8
Legionella 3.8
tumorigenesis 3.7
CJD 3.7
eastern equine encephalitis 3.7
B-cell lymphomas 3.7
emotional disturbance 3.7
LDLR 3.7
HOS 3.7
Hippel 3.7
PDB 3.7
blood disorder 3.7
AAT deficiency 3.6
FUS 3.6
motor aphasia 3.6
rhabdomyoma 3.6
NMS 3.6
Adenoid cystic carcinoma 3.6
Recruitment 3.6
DiGeorge syndrome 3.5
RDC 3.5
PIN 3.5
TMD 3.5
Fanconi 3.5
male infertility 3.4
Gerstmann 3.4
Haas 3.4
Franklin 3.4
acute promyelocytic leukemia 3.4
HEP 3.4
viral pneumonia 3.4
ERS 3.3
myopathy 3.3
AGS 3.3
monocytic leukemia 3.3
Huntington's disease 3.3
virus infection 3.3
Larsen 3.2
Parkinson's disease 3.2
recurrent cancer 3.2
more...
Symptom
Flaccid dysarthria 11.8
male subfertility 4.8
loss of taste 4.3
irregular bleeding 4.3
starvation 3.2
ataxia 2.9
cachexia 2.7
bradykinesia 2.6
despair 2.2
dysarthria 2.0
twitching 1.8
myoclonus 1.8
pallor 1.5
hypotonia 1.3
colic 1.2
cerebellar ataxia 1.0
memory loss 1.0
respiratory distress 0.9
apathy 0.8
collapse 0.8
weakness 0.8
tremor 0.7
acute stress 0.7
hepatomegaly 0.3
spasticity 0.2
dystonia -0.2
hypothermia -0.2
splenomegaly -0.4
agitation -0.7
sleepiness -0.8
erythema -0.8
seizures -0.9
exhaustion -0.9
anorexia -0.9
diarrhea -1.0
acidity -1.0
fatigue -1.8
pain -3.2
anesthesia -3.9
Drug
Parkin 7.2
Parkin 7.2
AMC 6.2
lysine 5.7
RBT 5.7
Bortezomib 5.6
ATV 4.3
GEO 4.2
MDM 4.1
Maltose 4.0
Singular 3.9
Dihydro 3.8
Papain 3.7
Retinoic acid 3.7
RFP 3.6
Glide 3.5
Lenalidomide 3.5
ACT 3.4
Amiloride 3.3
TAT 3.2
Xanthium 3.1
Fraction 3.1
Amiloride 3.0
NVP 2.9
TAK 2.9
Ketoconazole 2.8
CTC 2.8
Kenyan 2.7
L-tyrosine 2.6
Gefitinib 2.6
ROS 2.6
CTC 2.5
Fluconazole 2.5
BLM 2.4
Gleevec 2.4
IFN-beta 2.3
BH4 2.3
balanced salt solution 2.3
Adriamycin 2.2
DM1 2.2
TAC 2.2
Gelatin 2.1
Glutathione 2.0
Itraconazole 1.9
ADR 1.8
Biopolymers 1.8
Paraffin 1.8
Capsicum 1.7
Glycerol 1.7
ROC 1.5
Nitric Oxide 1.5
Forskolin 1.5
HCG 1.5
Alliance 1.5
Asn 1.3
Heme 1.2
ADM 1.2
PCP 1.0
Fluorescein 1.0
p75 0.9
EE2 0.9
Ethanol 0.6
Gel 0.6
Angiotensin II 0.5
NADH 0.0
MAP -0.1
Monit -0.3
ABC -0.3
IFN-gamma -0.4
citric acid -0.4
CSF -0.5
Leaf -0.6
ascorbate -0.6
IL-2 -1.0
caffeine -1.6
Asthma -1.8
Cardiovasc -3.2
Dermatol -5.2
Enzyme
ubiquityl-calmodulin synthetase 11.8
isopeptidase 9.4
carboxypeptidase 1 9.3
ubiquitin-protein ligase 9.0
proteasome ATPase 8.8
PHD 8.3
proteasome 8.1
assemblin 7.5
arginyltransferase 7.3
IKK 6.9
10-formyltetrahydrofolate dehydrogenase 6.7
conjugase 6.7
bleomycin hydrolase 6.5
pyrrolysyl-tRNA synthetase 6.1
peptidyl-tRNA hydrolase 6.1
DAHP synthase 6.0
aminopeptidase I 6.0
myo-inositol-1-phosphate synthase 5.8
Protein 2 5.7
GMP synthetase 5.6
protein disulfide-isomerase 5.5
oxoglutarate dehydrogenase 5.5
3C protease 5.5
NMT 5.5
phytoene synthase 5.2
starch synthase 5.1
acetylesterase 5.1
calpain 3 5.1
choline kinase 5.1
PRT 5.0
aspartyl-tRNA synthetase 5.0
NCP 4.9
lysyl endopeptidase 4.9
spermidine/spermine N1-acetyltransferase 4.9
CEP 4.9
polo-like kinase 1 4.8
papain 4.7
protein phosphatase 2A 4.6
MEKK1 4.6
4CL 4.5
carboxypeptidase Y 4.5
glyceraldehyde-3-phosphate dehydrogenase 4.5
MsrA 4.5
Omi/HtrA2 4.4
Lys4 4.4
oxidosqualene cyclase 4.4
CEP 4.3
rhodanese 4.3
glyceraldehyde-3-phosphate dehydrogenase 4.3
glyceraldehyde-3-phosphate dehydrogenase 4.2
glyceraldehyde-3-phosphate dehydrogenase 4.2
ACC synthase 4.2
cathepsin B 4.1
glyceraldehyde-3-phosphate dehydrogenase 4.1
phosphorylase kinase 4.0
p100 4.0
trehalase 4.0
SCP 4.0
APC 4.0
uroporphyrinogen decarboxylase 4.0
histone demethylase 4.0
TPP 3.9
cytidine deaminase 3.9
cathepsin S 3.9
O-GlcNAc transferase 3.9
TGT 3.8
ECH 3.8
arginine decarboxylase 3.8
SPT 3.8
phosphoglycerate kinase 3.8
prenyltransferase 3.7
caspase-8 3.7
cathepsin D 3.6
glutathione S-transferase 3.6
prenyltransferase 3.6
TSA 3.6
carboxypeptidase B 3.6
prenyltransferase 3.6
arginine decarboxylase 3.6
p-nitrophenylphosphatase 3.6
cysteine synthase 3.6
AMPK 3.5
beta-glucuronidase 3.5
TPP 3.5
NAT 3.5
3-hydroxyacyl-CoA dehydrogenase 3.4
beta-1,3-glucanase 3.4
3-hydroxyacyl-CoA dehydrogenase 3.4
beta-1,3-glucanase 3.4
methionine adenosyltransferase 3.4
adenine phosphoribosyltransferase 3.4
cdc2 3.4
PGM 3.4
ornithine decarboxylase 3.4
insulin-degrading enzyme 3.3
TOR 3.3
MAT 3.3
chalcone synthase 3.3
peptidyl-prolyl cis-trans isomerase 3.2
TAT 3.2
m-calpain 3.2
pyruvate decarboxylase 3.1
GRK2 3.1
MAT 3.1
peroxiredoxin 3.1
ATPase 3.1
S-adenosylmethionine decarboxylase 3.1
SPT 3.0
histone acetyltransferase 3.0
chitin synthase 3.0
AMP-activated protein kinase 3.0
calcium pump 2.9
protein kinase 2.9
ADP-ribosyltransferase 2.9
nucleotidase 2.8
ADP-ribosyltransferase 2.8
calcineurin 2.8
lysozyme 2.8
AMPK 2.7
15-lipoxygenase 2.7
dihydrofolate reductase 2.7
uricase 2.6
Thy1 2.6
PARP 2.6
alpha-ketoglutarate dehydrogenase 2.5
trypsin 2.5
rubisco 2.5
phosphoglucomutase 2.4
GSK 2.4
firefly luciferase 2.4
phenylalanine hydroxylase 2.4
ribonucleotide reductase 2.4
mitogen-activated protein kinase 2.3
transpeptidase 2.3
glucocerebrosidase 2.3
luciferase 2.3
carbonic anhydrase 2.3
ribonucleotide reductase 2.3
farnesyltransferase 2.3
alpha-mannosidase 2.3
triphosphatase 2.3
caspase-1 2.2
furin 2.2
caspase-3 2.2
leucine aminopeptidase 2.2
invertase 2.2
granzyme B 2.2
PRA 2.1
chloramphenicol acetyltransferase 2.1
aconitase 2.1
thymidylate synthase 2.0
prolyl hydroxylase 2.0
beta-galactosidase 2.0
demethylase 2.0
phosphatidylinositol 3-kinase 2.0
PAM 2.0
MPP 2.0
botulinum neurotoxin 2.0
phosphoinositide 3-kinase 1.9
DCF 1.9
more...
Compound
Ubiquitin 12.8
CUE 9.8
Xanthosine 9.0
RUB 8.8
4-piperidinone 8.6
Naphthazarin 8.6
Naphthazarin 8.5
Kaurenoic acid 7.8
TKB 7.4
UPP 7.3
CHIP 7.0
PTAP 7.0
2-butenoic acid 6.8
DVC 6.7
4-phenylbutanoic acid 6.7
Castanospermine 6.6
Cbl 6.6
2-butenoic acid 6.5
Molybdenum cofactor 6.5
RD4 6.4
Withaferin A 6.4
2-cyclopenten-1-one 6.3
Beauvericin 6.3
OLN 6.1
NIX 6.1
AAA 6.0
thiirane 6.0
Z-Gly 5.9
Gambogic acid 5.8
Formin 5.8
lysine 5.7
Dimethyl fumarate 5.7
prostaglandin J2 5.7
benzenesulfonyl fluoride 5.6
TCN 5.6
DOA 5.5
Temsirolimus 5.5
DPA 5.4
Thymoquinone 5.4
BTG 5.4
BTG 5.3
Elan 5.3
NOXA 5.3
Elan 5.0
ASK 4.9
Mesna 4.9
4-phenyl-1,2,3,6-tetrahydropyridine 4.9
AFC 4.8
4-Hydroxynonenal 4.8
Angiotensin I 4.8
SSH 4.8
ECS 4.7
phenyl acetate 4.6
pyrroline-5-carboxylate 4.6
MAK 4.6
Honokiol 4.6
PYR 4.5
TDP 4.5
Puromycin 4.4
Daidzein 4.4
CoM 4.4
Thymine 4.3
Poly I 4.3
K19 4.2
3-methylhistidine 4.2
TBC 4.2
APT 4.2
PHE 4.2
AIR 4.2
PDB 4.2
norvaline 4.1
AAT 4.1
Tumor Necrosis Factor 4.1
norvaline 4.0
DTP 4.0
Maltose 4.0
Histidine 3.9
methyl methanesulfonate 3.9
NFS 3.9
PPi 3.9
Vimentin 3.8
ASN 3.8
TAR 3.8
HOG 3.8
Astaxanthin 3.7
40S 3.7
Glu-Glu 3.7
carbamyl phosphate 3.7
Ferulic acid 3.7
BGE 3.7
Ferulic acid 3.7
Camptothecin 3.6
Camptothecin 3.6
C2H2 3.6
Camptothecin 3.6
Cycloheximide 3.6
Isoform 3.6
dCMP 3.6
ABA 3.5
NTA 3.5
alpha-ketoisocaproate 3.4
Dithiothreitol 3.4
TPP 3.4
HAP 3.4
HEP 3.4
HMG-CoA 3.4
LIN 3.3
cysteine 3.3
Uracil 3.3
Amiloride 3.3
ABA 3.3
PIN 3.3
IBA 3.3
Lea 3.2
GA3 3.2
DPC 3.2
DPC 3.2
Dithiothreitol 3.2
Histone 3.2
Gly 3.2
IAA 3.1
INT 3.1
ATP 3.1
Cysteine 3.1
POA 3.1
Rapamycin 3.1
Acetazolamide 3.1
VM-26 3.1
ITC 3.1
TPP 3.1
Casein 3.1
1H-imidazole 3.0
IBA 3.0
TCC 3.0
Proline 3.0
Choline 3.0
E-64 3.0
IAA 3.0
aldehyde 3.0
Methionine 2.9
DTT 2.9
PDH 2.9
Collagenase 2.9
Ketoconazole 2.9
Eosin 2.9
Hypo 2.9
CAA 2.8
ACN 2.8
PPI 2.8
NPA 2.8
DTT 2.8
Creatine 2.8
RU-486 2.8
CAP 2.8
Ile 2.7
DAP 2.7
SET 2.7
DAP 2.7
DAG 2.7
Alizarin 2.7
more...