Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P61278 (somatostatin)
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Human Gene/Protein
SP8 protein 10.5
GPR107 protein 10.5
somatostatin 10.5
ASTN1 protein 10.5
G protein-coupled receptor 107 10.5
SSTR1 10.3
SRIF 10.2
SSTR2 10.2
SSTR4 10.2
SSTR5 10.1
SSTR3 10.1
somatostatin receptor 1 10.0
SST3 9.8
somatostatin receptor 9.8
somatostatin receptor 2 9.7
DC25 9.5
PAX4 protein 9.5
netrin G2 9.5
astrotactin 1 9.5
v-maf musculoaponeurotic fibrosarcoma oncogene homolog 9.5
RAP1 GTPase activating protein 9.5
Preprotachykinin B 9.5
F-box and leucine-rich repeat protein 20 9.5
gastric juice peptide 9.5
sodium/hydrogen exchanger 8 9.5
FLJ32356 9.5
KIAA1200 9.5
regulator of G protein signaling 12 9.5
MTLRP 9.5
cortistatin 9.4
Somatostatin receptor type 2 9.4
SMS 9.3
DC32 9.2
Aryl hydrocarbon receptor interacting protein 9.1
G protein-coupled receptor 25 8.9
parathyroid hormone receptor 2 8.9
skeletal muscle C-protein 8.9
somatostatin receptor 3 8.9
regulator of G-protein signaling 6 8.9
GHRH-R 8.8
pancreatic polypeptide 8.8
RAP1GA1 8.5
somatostatin receptor type 5 8.5
glutamate receptor, ionotropic, kainate 2 8.5
delta-6 fatty acid desaturase 8.5
TCEB3C 8.5
GPR20 8.5
PSS2 8.4
GPR107 8.4
GHRH 8.3
Lhx6 8.3
growth hormone releasing hormone 8.3
SOM 8.2
motilin 8.2
protocadherin 20 8.2
Neuroligin 3 8.2
KCNS3 8.2
MEN1 protein 8.2
astrotactin 2 8.2
SSR2 8.1
gastrin 8.0
LHX6 8.0
SST 8.0
IQSEC3 7.9
PSS1 7.9
gastric inhibitory polypeptide 7.9
NAPG 7.9
GPR45 7.9
OR1G1 7.9
neurotensin 7.9
bombesin 7.9
LAR 7.8
vasoactive intestinal peptide 7.7
LIM homeobox 1 7.7
ERp27 7.7
NRG-4 7.7
GPR22 7.7
preprotachykinin B 7.7
parvalbumin alpha 7.7
PPP1R2 7.7
more...
Disease
Congenital microvillous atrophy 10.5
Left sided heart 10.5
Idiopathic diarrhea 10.5
Gastric ileus 10.5
Symmer's pipe-stem fibrosis 10.5
Somatostatinoma 9.8
Somatostatinomas 9.8
Hypoglucagonemia 9.7
somatostatinoma 9.6
Carcinoid crisis 9.5
gastrectasis 9.5
Unilateral vision loss 9.5
recurrent childhood medulloblastoma 9.5
Ulcer haemorrhage 9.5
Malignant gastrinoma 9.5
Islet cell adenoma 9.5
TSH secreting adenoma 9.2
Tumor-induced hypoglycemia 9.2
SMS 9.1
Diabetic diarrhea 8.9
Atypical adenoma 8.9
Gastric motor dysfunction 8.9
Late-onset cystinosis 8.9
TSH hypersecretion 8.9
VIPoma 8.8
GH-secreting pituitary adenoma 8.7
TSHoma 8.6
Adrenocortical hyperplasia 8.5
Mesenteric fibrosis 8.5
Mycobacterium avium complex lymphadenitis 8.5
Hepatic artery occlusion 8.5
WDHA syndrome 8.3
glucagonoma 8.2
carcinoid syndrome 8.2
Cerebellar medulloblastoma 8.2
Endocrine pancreas 8.2
Chronic superficial gastritis 8.2
Endocrine pancreas 8.2
acromegaly 8.1
GIN 8.1
reflex disorder 7.9
Duodenal carcinoid 7.9
Malignant paraganglioma 7.9
G cell hyperplasia 7.8
gastrinoma 7.8
Insulin hypoglycemia 7.7
C cell adenoma 7.7
AA1 7.7
postgastrectomy dumping syndrome 7.5
Postoperative atelectasis 7.5
Malignant insulinoma 7.5
neuroendocrine tumor 7.5
pancreatic gastrinoma 7.4
Drug-induced neutropenia 7.3
Typical carcinoid 7.3
ovarian mixed germ cell tumor 7.3
Android obesity 7.3
Necrolytic migratory erythema 7.3
Congenital chylothorax 7.3
stage II gastric cancer 7.2
pyloric dysfunction 7.2
Islet cell tumor 7.2
ACTH-secreting pituitary adenoma 7.1
Zollinger-Ellison syndrome 7.1
pituitary cancer 7.1
Nesidioblastosis 7.0
Biventricular hypertrophy 7.0
ACTH-producing pituitary tumor 7.0
DIPNECH 7.0
Endotoxicosis 7.0
Gastrointestinal angiodysplasia 7.0
carcinoid 7.0
Polycystic liver disease 7.0
Pancreatic ascites 7.0
dumping syndrome 6.9
Chronic hypotension 6.9
SCN1 6.9
Microcystic adenoma 6.9
Gastric carcinoid 6.9
Carcinoid heart disease 6.9
more...
Symptom
Gurgling 10.5
Sharp pain 8.2
Lid lag 7.9
Paroxysmal hypertension 6.8
Mechanical pain 5.4
retrosternal discomfort 5.4
Food intolerance 5.3
musculoskeletal impairment 5.1
stomach distension 5.1
abdominal cramps 5.0
stomach cramps 4.9
Deafferentation 4.7
Severe diarrhea 4.7
flushing 4.5
autodigestion 4.5
generalized rash 4.3
Cushingoid 4.3
excessive sweating 4.1
Motor dysfunction 4.1
male puberty 4.1
POA 4.0
ketonuria 4.0
sighing 3.9
chyluria 3.9
Cushingoid 3.8
phosphatemia 3.7
Visceral pain 3.6
female puberty 3.6
diarrhea 3.4
abdominal discomfort 3.3
nocturnal polyuria 3.3
blushing 3.0
Regurgitation 3.0
Neurologic symptoms 3.0
epigastric pain 2.9
impaired motor coordination 2.9
tonic seizure 2.8
labored breathing 2.8
constipation 2.6
bloating 2.6
bone pain 2.6
periorbital edema 2.5
athetosis 2.5
intestinal bleeding 2.4
polydipsia 2.4
hypoproteinemia 2.3
prostatism 2.3
Gastrointestinal symptoms 2.3
hyperemesis 2.3
seizures 2.2
right lower quadrant pain 2.2
acute stress 2.2
Excitability 2.2
No adverse effect 2.2
Physical findings 2.1
abdominal pain 2.1
leg edema 2.1
right upper quadrant pain 2.1
emaciation 2.0
erythema 2.0
prostration 2.0
polyuria 1.9
acidity 1.9
hunger 1.8
rigors 1.8
abdominal fullness 1.8
belching 1.8
anorexia 1.8
HSA 1.8
chronic constipation 1.8
neuralgia 1.7
nausea 1.7
orofacial pain 1.6
tenesmus 1.6
wheezing 1.6
nausea and vomiting 1.6
rundown 1.5
cancer pain 1.5
memory loss 1.5
analgesia 1.5
more...
Drug
SDZ 215-811 10.5
Vapreotide 10.3
Sandostatin 9.9
Sandostatin 9.9
Depreotide 9.8
OctreoScan 9.7
Sandostatin LAR 9.6
Pegvisomant 9.5
Aclatonium napadisilate 9.5
Lanreotide acetate 9.5
Geref 8.9
Geref 8.9
GRF 8.0
Tesamorelin 7.7
Mecasermin rinfabate 7.7
GHRP 7.6
Itopride hydrochloride 7.5
Terlipressin 7.4
Terlipressin 7.4
Axokine 7.3
Secretin 7.2
Limaprost 7.2
Bisacodyl 7.1
Ecabet sodium 7.0
Growth hormone 6.9
L 364718 6.9
Iletin II 6.9
Glucagon 6.8
Methyltyrosine 6.7
Growth hormone 6.6
Enprostil 6.6
Loxiglumide 6.6
Lafutidine 6.5
Alrestatin 6.5
Gastrin I 6.2
Proglumide 6.2
Gonadorelin 6.0
Rioprostil 6.0
Cetrorelix 5.9
Humulin 5.7
Everolimus 5.4
Metoclopramide hydrochloride 5.4
Parlodel 5.3
Gastrozepin 5.2
Ciprofibrate 5.2
Hoelen 5.1
Forskolin 5.1
Regitine 5.1
Omeprazole 5.1
Stannous chloride 5.1
Myotrophin 5.1
Parlodel 5.0
Progabide 5.0
Zinc sulfate 5.0
Zinc sulfate 4.9
Atropine 4.9
1-Deoxynojirimycin 4.9
Sodium ascorbate 4.7
Beraprost 4.7
Liposyn 4.7
Intron A 4.7
Morphine sulfate 4.6
Alarin 4.6
Atabrine 4.6
Tham 4.6
Luteinizing 4.6
DMSA 4.5
Primperan 4.5
Intron A 4.5
Dextran sulfate sodium 4.4
Intron A 4.4
Vandetanib 4.4
Tegaserod 4.4
Zebularine 4.4
Marimastat 4.3
Phentolamine 4.3
Velban 4.3
Catapres 4.2
Gliclazide 4.2
Tegaserod 4.1
more...
Enzyme
peptide hormone inactivating endopeptidase 8.9
SST 8.0
yapsin 1 7.6
calpain 9 7.5
proprotein convertase 2 6.7
pyroglutamyl peptidase II 5.9
neurolysin 5.9
Lys4 5.6
protein acyltransferase 5.6
choline acetyltransferase 5.5
nardilysin 5.5
histidine decarboxylase 5.4
dopamine beta-hydroxylase 5.4
NADPH-diaphorase 5.3
adenylate cyclase 5.0
glutamate decarboxylase 5.0
tyrosine hydroxylase 4.9
PTPase 4.9
thimet oligopeptidase 4.8
phenylethanolamine N-methyltransferase 4.8
GPH 4.7
pantetheinase 4.7
acetyl-CoA hydrolase 4.7
histone-lysine N-methyltransferase 4.5
aspartate semialdehyde dehydrogenase 4.4
diaphorase 4.4
myo-inositol oxygenase 4.2
endo-N 4.2
enolase 4.2
KAR 4.1
PTR 4.1
matrix metalloproteinase 14 4.0
aromatic L-amino acid decarboxylase 4.0
tryptophan hydroxylase 4.0
glucokinase 3.9
carboxypeptidase E 3.9
dynamin GTPase 3.8
GRK5 3.7
pepsin 3.7
prostate-specific membrane antigen 3.6
PRPP synthetase 3.6
proprotein convertase 3.6
GRK2 3.5
GABA transaminase 3.4
diaphorase 3.3
carboxypeptidase B 3.2
NQO1 3.2
endothelin-converting enzyme 3.2
type 1 protein phosphatase 3.1
VIP1 3.1
KLK7 3.0
GAS 2.9
CD10 2.9
carboxypeptidase A 2.9
prolyl endopeptidase 2.9
acetylcholinesterase 2.9
phosphatidylinositol-4,5-bisphosphate 3-kinase 2.9
lysin 2.8
NO synthase 2.8
collagenase 2.7
aminopeptidase B 2.7
sucrase 2.7
arylalkylamine N-acetyltransferase 2.7
phosphatidylinositol 4-kinase 2.7
chloramphenicol acetyltransferase 2.6
oxytocinase 2.6
eEF2 kinase 2.6
alanine aminopeptidase 2.6
insulin-degrading enzyme 2.6
clostripain 2.5
peroxidase 2.5
lipase 2.5
phosphodiesterase 2.5
NOS 2.5
DOPA decarboxylase 2.5
protein kinase C 2.4
phospholipase C 2.4
guanylate cyclase 2.4
SpeB 2.4
cytochrome P-450scc 2.4
more...
Compound
Octreotide 9.7
N,N'-dimethyl-N,N'-diphenylurea 9.5
Sodium isethionate 9.5
2,3-diaminosuccinic acid 8.9
CYN 8.9
C8H16N2O2 8.5
Synthalin 8.5
4'-Phosphopantetheine 8.5
Picrotin 8.2
V 12 8.2
Saprol 8.2
Asperlicin 8.2
Depostat 7.9
TIPPS 7.9
Isethionate 7.7
Cysteamine 7.7
Pyridostigmine 7.5
C3H6O3 7.5
Pantethine 7.3
BON 7.2
Secretin 7.1
Hydroflumethiazide 7.0
Glucagon 6.8
Diadenosine triphosphate 6.8
Neurotensin 6.8
Pentagastrin 6.7
Yohimbine hydrochloride 6.7
CPDS 6.7
4-fluorobenzamide 6.7
X 48 6.7
Lys-vasopressin 6.6
NBTGR 6.6
NBTGR 6.6
NBTGR 6.6
NBTGR 6.6
Substance P 6.6
cyclohexylacetic acid 6.5
Arg-vasopressin 6.4
Mannoheptulose 6.4
2-aminocyclopentanecarboxylic acid 6.4
Gallein 6.4
Cabergoline 6.4
TRH 6.3
DADT 6.3
Gallein 6.3
L-Homocysteic acid 6.2
Tripalmitin 6.2
Histidyl-proline diketopiperazine 6.2
Morphiceptin 6.2
Tranzer 6.2
Resiniferatoxin 6.1
(aminooxy)acetic acid 6.0
Gonadorelin 6.0
DVC 5.9
Diazoxide 5.9
1,4,7,10-tetraazacyclododecane 5.9
1-aminocyclopentanecarboxylic acid 5.9
1-aminocyclopentanecarboxylic acid 5.9
4-fluorobenzaldehyde 5.9
New Fuchsin 5.9
4-fluorobenzaldehyde 5.9
p-Chloroamphetamine 5.8
3-(2-naphthyl)alanine 5.8
Oxythiamine 5.8
Lappaconitine 5.8
3,4-D 5.8
Endomorphin-2 5.8
Methyl linoleate 5.7
Glyceraldehyde 5.7
Phenylglycine 5.7
Calcitonin 5.7
Methionine enkephalin 5.6
MK-329 5.6
H-69 5.6
MMU 5.5
DMHP 5.4
G17 5.4
TETA 5.4
Acetonitrile, 5.4
Cosyntropin 5.3
more...