Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P61278 (somatostatin)
22,083 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
somatostatin 22083
insulin 4199
glucagon 3261
growth hormone 2087
SRIF 1933
gastrin 1776
substance P 1745
Sep 1438
somatostatin receptor 1155
cholecystokinin 1131
neuropeptide Y 1069
polypeptide 1034
pancreatic polypeptide 979
calcitonin 950
Mol 811
neurotensin 768
vasoactive intestinal peptide 710
parvalbumin 708
GHRH 705
beta-endorphin 644
gut 639
SMS 603
bombesin 591
secretin 549
prolactin 506
GABA 470
galanin 464
vasoactive intestinal peptide (VIP) 460
vasopressin 439
ACTH 419
adenylate cyclase 412
SSTR2 323
AMP 321
motilin 320
tyrosine hydroxylase 319
VIP 311
ghrelin 308
TRH 304
IGF-I 299
CCK 295
chromogranin A 281
calretinin 278
Growth hormone 268
calbindin 267
CA1 266
oxytocin 258
SSTR5 240
nitric oxide synthase 238
peroxidase 237
thyrotropin-releasing hormone 237
SSTR1 232
dynorphin 232
amylase 210
Gen 209
choline acetyltransferase 203
adenylyl cyclase 203
LHRH 196
neuron-specific enolase 191
PRL 187
corticotropin-releasing factor 184
gastrin-releasing peptide 182
axonal 179
insulin-like growth factor 172
5-hydroxytryptamine 170
GTP 163
synaptophysin 161
epidermal growth factor 160
BOD 155
peptide YY 154
mTOR 153
MRI 150
IGF-1 150
ATP 146
NPY 142
insulin-like growth factor I 141
interferon 140
Neuropeptide Y 137
cortistatin 136
SSTR3 135
SST 134
more...
Disease
tumor 2442
diabetes 1236
cancer 1112
acromegaly 771
metastases 674
carcinoid 629
SMS 603
hypoglycemia 470
hyperglycemia 442
pertussis 395
Alzheimer's disease 354
carcinoma 350
neuroendocrine tumor 303
tumor growth 260
carcinoid syndrome 260
adenoma 256
hyperinsulinemia 250
depression 219
Pituitary 218
SEM 216
insulinoma 211
liver metastases 205
pituitary adenoma 205
obesity 205
pituitary tumor 188
medullary thyroid carcinoma 175
varices 168
adenocarcinoma 162
multiple endocrine neoplasia 156
type 2 diabetes 153
breast cancer 152
cirrhosis 145
epilepsy 144
acute pancreatitis 139
hypertension 137
pancreatitis 137
Pancreas 130
Pancreas 129
gallstones 122
gastrinoma 119
prostate cancer 117
Zollinger-Ellison syndrome 115
dementia 114
portal hypertension 112
Cushing's syndrome 109
schizophrenia 109
primary tumor 108
pheochromocytoma 107
pancreatic cancer 107
glucose intolerance 107
Cushing's disease 107
somatostatinoma 106
chronic renal failure 103
neuroblastoma 102
glucagonoma 101
Huntington's disease 97
type 1 diabetes 96
duodenal ulcer 92
ischemia 92
cold 90
Parkinson's disease 90
hyperthyroidism 85
peptic ulcer 83
esophageal varices 80
cholera 75
lung cancer 73
paraganglioma 72
lymphoma 70
neuroendocrine carcinoma 70
chronic pancreatitis 68
hepatocellular carcinoma 65
hypothyroidism 65
celiac disease 64
small cell lung cancer 62
temporal lobe epilepsy 62
gastritis 60
tumor progression 59
plaque 58
chylothorax 57
tumorigenesis 55
more...
Symptom
diarrhea 421
pain 314
seizures 264
anesthesia 110
flushing 103
abdominal pain 93
headache 81
analgesia 54
nausea 52
vomiting 51
constipation 43
starvation 40
acidity 39
erythema 36
fatigue 36
anorexia 33
nausea and vomiting 20
hypothermia 19
epigastric pain 18
weakness 16
discomfort 16
discomfort 16
acute stress 15
hunger 14
bone pain 13
dyspnea 13
abdominal discomfort 12
abdominal cramps 12
respiratory distress 12
arthralgia 11
overweight 11
tremor 11
wheezing 10
cachexia 10
exhaustion 9
polyuria 8
ataxia 8
functional recovery 8
polydipsia 8
excessive sweating 7
HSA 7
dystonia 7
dizziness 7
memory loss 7
bloating 7
ketonuria 6
Ill 6
acute pain 6
sleepiness 6
cancer pain 6
agitation 6
POA 6
collapse 6
paresthesia 6
lethargy 5
low back pain 5
hypercapnia 5
chest pain 5
syncope 5
hepatomegaly 5
autodigestion 5
hypoproteinemia 4
back pain 4
neuralgia 4
cough 4
shortness of breath 4
angina 4
Wind 4
myoclonus 4
regurgitation 3
Deafferentation 3
emaciation 3
Cushingoid 3
intestinal bleeding 3
exertional dyspnea 3
chronic constipation 3
hemoptysis 3
cyanosis 3
chorea 3
Welt 3
more...
Drug
Glucagon 297
Growth hormone 253
Growth hormone 211
Sandostatin 205
Sandostatin 205
GRF 173
Gel 95
lysine 92
CSF 90
GHRP 78
Secretin 75
Atropine 69
Forskolin 63
ENT 61
Nephron 56
Asn 52
Sandostatin LAR 46
Pegvisomant 42
Histamine 42
Dermatol 38
OctreoScan 36
Portal 36
nitroglycerin 31
Cardiovasc 30
Omeprazole 24
Paraffin 23
PTH 23
IFN-gamma 21
Everolimus 21
IL-2 19
Indomethacin 19
Leaf 18
caffeine 17
Luteinizing 17
EE2 16
Phentolamine 16
ICI 16
DNase I 15
Biopolymers 14
Clonidine 13
Terlipressin 13
Terlipressin 13
DMSA 12
ABC 12
Ethanol 12
MAP 11
Vapreotide 11
Theophylline 11
Alanine 10
Cimetidine 10
Gastro 10
DHT 10
Cimetidine 10
DHT 10
CaCl2 9
Angiotensin II 9
CaCl2 9
CaCl2 9
Fructose 9
Activin 9
Albumin 9
Cetrorelix 8
HCG 8
CAM 7
ascorbate 7
ADM 7
ETA 7
HCH 7
Kainic acid 7
PCB 6
Ringer's solution 6
Ranitidine 6
Retinoic acid 6
CTX 6
Ketoconazole 6
NADH 6
Bisacodyl 6
Apomorphine 6
Proglumide 6
CPT-11 5
more...
Enzyme
adenylate cyclase 426
tyrosine hydroxylase 312
peroxidase 262
protein kinase 235
choline acetyltransferase 204
protein kinase C 185
ERK 143
acetylcholinesterase 142
SST 134
mitogen-activated protein kinase 131
NADPH-diaphorase 104
trypsin 87
collagenase 85
pepsin 76
NO synthase 75
lipase 74
phosphodiesterase 73
phospholipase C 69
ATPase 69
renin 57
reverse transcriptase 55
CD10 50
glutamate decarboxylase 47
enolase 47
alkaline phosphatase 46
histidine decarboxylase 43
diaphorase 41
dopamine beta-hydroxylase 41
NQO1 40
diaphorase 40
catalase 34
luciferase 32
cholinesterase 31
guanylate cyclase 31
calcineurin 30
chymotrypsin 30
glucokinase 30
superoxide dismutase 29
NOS 28
acid phosphatase 28
caspase-3 25
AMPK 24
focal adhesion kinase 23
MEK 22
chloramphenicol acetyltransferase 22
RNase 22
PTPase 21
phospholipase A2 21
RNase 21
lipoxygenase 20
RNA polymerase 19
ACE 19
lactate dehydrogenase 19
tryptophan hydroxylase 19
transcriptase 19
lysozyme 16
urease 15
phosphatidylinositol 3-kinase 15
prostate-specific membrane antigen 15
phosphorylase 15
urease 15
thymidine kinase 14
alpha-glucosidase 14
ribonuclease 14
ribonuclease 14
carbonic anhydrase 13
kallikrein 13
alanine aminotransferase 13
ACS 13
thrombin 12
Lys4 12
CaMKII 12
phosphoenolpyruvate carboxykinase 12
phenylethanolamine N-methyltransferase 12
beta-galactosidase 11
phosphoinositide 3-kinase 11
furin 11
sucrase 11
GRK5 10
glyceraldehyde-3-phosphate dehydrogenase 10
more...
Compound
glucose 2661
Clin 1572
Dec 1538
calcium 1059
cAMP 694
arginine 571
Octreotide 560
Insulin 545
tyrosine 530
GABA 487
GABA 481
DNA 445
Phe 432
lysine 425
ACTH 422
sodium 413
TSH 381
TRH 355
AMP 334
water 326
glutamate 319
threonine 300
Glucagon 297
NH2 273
leucine 264
acetate 259
potassium 258
5-HT 254
noradrenaline 245
methionine 242
alanine 235
gamma-aminobutyric acid 220
Substance P 213
DTPA 187
GTP 164
His 163
nitric oxide 162
silver 150
phosphate 149
ATP 147
ethanol 142
Diabetol 116
galactose 109
Dopamine 104
acetic acid 102
iodine 101
glycerol 100
oxygen 98
Gly 97
Ile 92
Calcitonin 81
HCl 80
isoleucine 77
isoleucine 76
Cysteamine 75
Secretin 75
Thyroid 74
ACh 73
Adrenal 73
Neurotensin 73
sulfate 71
cGMP 70
Atropine 69
salt 69
NMDA 69
tryptophan 66
L-DOPA 65
Cereb 64
ADP 63
Forskolin 63
hydroxyindoleacetic acid 62
ADP 62
nitrogen 61
serine 61
alloxan 61
Neuronal 61
cysteine 61
ADP 61
urea 59
tryptophan 59
more...