Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P61278 (
somatostatin
)
22,083
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
somatostatin
22083
insulin
4199
glucagon
3261
growth hormone
2087
SRIF
1933
gastrin
1776
substance P
1745
Sep
1438
somatostatin receptor
1155
cholecystokinin
1131
neuropeptide Y
1069
polypeptide
1034
pancreatic polypeptide
979
calcitonin
950
Mol
811
neurotensin
768
vasoactive intestinal peptide
710
parvalbumin
708
GHRH
705
beta-endorphin
644
gut
639
SMS
603
bombesin
591
secretin
549
prolactin
506
GABA
470
galanin
464
vasoactive intestinal peptide (VIP)
460
vasopressin
439
ACTH
419
adenylate cyclase
412
SSTR2
323
AMP
321
motilin
320
tyrosine hydroxylase
319
VIP
311
ghrelin
308
TRH
304
IGF-I
299
CCK
295
chromogranin A
281
calretinin
278
Growth hormone
268
calbindin
267
CA1
266
oxytocin
258
SSTR5
240
nitric oxide synthase
238
peroxidase
237
thyrotropin-releasing hormone
237
SSTR1
232
dynorphin
232
amylase
210
Gen
209
choline acetyltransferase
203
adenylyl cyclase
203
LHRH
196
neuron-specific enolase
191
PRL
187
corticotropin-releasing factor
184
gastrin-releasing peptide
182
axonal
179
insulin-like growth factor
172
5-hydroxytryptamine
170
GTP
163
synaptophysin
161
epidermal growth factor
160
BOD
155
peptide YY
154
mTOR
153
MRI
150
IGF-1
150
ATP
146
NPY
142
insulin-like growth factor I
141
interferon
140
Neuropeptide Y
137
cortistatin
136
SSTR3
135
SST
134
more...
Disease
tumor
2442
diabetes
1236
cancer
1112
acromegaly
771
metastases
674
carcinoid
629
SMS
603
hypoglycemia
470
hyperglycemia
442
pertussis
395
Alzheimer's disease
354
carcinoma
350
neuroendocrine tumor
303
tumor growth
260
carcinoid syndrome
260
adenoma
256
hyperinsulinemia
250
depression
219
Pituitary
218
SEM
216
insulinoma
211
liver metastases
205
pituitary adenoma
205
obesity
205
pituitary tumor
188
medullary thyroid carcinoma
175
varices
168
adenocarcinoma
162
multiple endocrine neoplasia
156
type 2 diabetes
153
breast cancer
152
cirrhosis
145
epilepsy
144
acute pancreatitis
139
hypertension
137
pancreatitis
137
Pancreas
130
Pancreas
129
gallstones
122
gastrinoma
119
prostate cancer
117
Zollinger-Ellison syndrome
115
dementia
114
portal hypertension
112
Cushing's syndrome
109
schizophrenia
109
primary tumor
108
pheochromocytoma
107
pancreatic cancer
107
glucose intolerance
107
Cushing's disease
107
somatostatinoma
106
chronic renal failure
103
neuroblastoma
102
glucagonoma
101
Huntington's disease
97
type 1 diabetes
96
duodenal ulcer
92
ischemia
92
cold
90
Parkinson's disease
90
hyperthyroidism
85
peptic ulcer
83
esophageal varices
80
cholera
75
lung cancer
73
paraganglioma
72
lymphoma
70
neuroendocrine carcinoma
70
chronic pancreatitis
68
hepatocellular carcinoma
65
hypothyroidism
65
celiac disease
64
small cell lung cancer
62
temporal lobe epilepsy
62
gastritis
60
tumor progression
59
plaque
58
chylothorax
57
tumorigenesis
55
more...
Symptom
diarrhea
421
pain
314
seizures
264
anesthesia
110
flushing
103
abdominal pain
93
headache
81
analgesia
54
nausea
52
vomiting
51
constipation
43
starvation
40
acidity
39
erythema
36
fatigue
36
anorexia
33
nausea and vomiting
20
hypothermia
19
epigastric pain
18
weakness
16
discomfort
16
discomfort
16
acute stress
15
hunger
14
bone pain
13
dyspnea
13
abdominal discomfort
12
abdominal cramps
12
respiratory distress
12
arthralgia
11
overweight
11
tremor
11
wheezing
10
cachexia
10
exhaustion
9
polyuria
8
ataxia
8
functional recovery
8
polydipsia
8
excessive sweating
7
HSA
7
dystonia
7
dizziness
7
memory loss
7
bloating
7
ketonuria
6
Ill
6
acute pain
6
sleepiness
6
cancer pain
6
agitation
6
POA
6
collapse
6
paresthesia
6
lethargy
5
low back pain
5
hypercapnia
5
chest pain
5
syncope
5
hepatomegaly
5
autodigestion
5
hypoproteinemia
4
back pain
4
neuralgia
4
cough
4
shortness of breath
4
angina
4
Wind
4
myoclonus
4
regurgitation
3
Deafferentation
3
emaciation
3
Cushingoid
3
intestinal bleeding
3
exertional dyspnea
3
chronic constipation
3
hemoptysis
3
cyanosis
3
chorea
3
Welt
3
more...
Drug
Glucagon
297
Growth hormone
253
Growth hormone
211
Sandostatin
205
Sandostatin
205
GRF
173
Gel
95
lysine
92
CSF
90
GHRP
78
Secretin
75
Atropine
69
Forskolin
63
ENT
61
Nephron
56
Asn
52
Sandostatin LAR
46
Pegvisomant
42
Histamine
42
Dermatol
38
OctreoScan
36
Portal
36
nitroglycerin
31
Cardiovasc
30
Omeprazole
24
Paraffin
23
PTH
23
IFN-gamma
21
Everolimus
21
IL-2
19
Indomethacin
19
Leaf
18
caffeine
17
Luteinizing
17
EE2
16
Phentolamine
16
ICI
16
DNase I
15
Biopolymers
14
Clonidine
13
Terlipressin
13
Terlipressin
13
DMSA
12
ABC
12
Ethanol
12
MAP
11
Vapreotide
11
Theophylline
11
Alanine
10
Cimetidine
10
Gastro
10
DHT
10
Cimetidine
10
DHT
10
CaCl2
9
Angiotensin II
9
CaCl2
9
CaCl2
9
Fructose
9
Activin
9
Albumin
9
Cetrorelix
8
HCG
8
CAM
7
ascorbate
7
ADM
7
ETA
7
HCH
7
Kainic acid
7
PCB
6
Ringer's solution
6
Ranitidine
6
Retinoic acid
6
CTX
6
Ketoconazole
6
NADH
6
Bisacodyl
6
Apomorphine
6
Proglumide
6
CPT-11
5
more...
Enzyme
adenylate cyclase
426
tyrosine hydroxylase
312
peroxidase
262
protein kinase
235
choline acetyltransferase
204
protein kinase C
185
ERK
143
acetylcholinesterase
142
SST
134
mitogen-activated protein kinase
131
NADPH-diaphorase
104
trypsin
87
collagenase
85
pepsin
76
NO synthase
75
lipase
74
phosphodiesterase
73
phospholipase C
69
ATPase
69
renin
57
reverse transcriptase
55
CD10
50
glutamate decarboxylase
47
enolase
47
alkaline phosphatase
46
histidine decarboxylase
43
diaphorase
41
dopamine beta-hydroxylase
41
NQO1
40
diaphorase
40
catalase
34
luciferase
32
cholinesterase
31
guanylate cyclase
31
calcineurin
30
chymotrypsin
30
glucokinase
30
superoxide dismutase
29
NOS
28
acid phosphatase
28
caspase-3
25
AMPK
24
focal adhesion kinase
23
MEK
22
chloramphenicol acetyltransferase
22
RNase
22
PTPase
21
phospholipase A2
21
RNase
21
lipoxygenase
20
RNA polymerase
19
ACE
19
lactate dehydrogenase
19
tryptophan hydroxylase
19
transcriptase
19
lysozyme
16
urease
15
phosphatidylinositol 3-kinase
15
prostate-specific membrane antigen
15
phosphorylase
15
urease
15
thymidine kinase
14
alpha-glucosidase
14
ribonuclease
14
ribonuclease
14
carbonic anhydrase
13
kallikrein
13
alanine aminotransferase
13
ACS
13
thrombin
12
Lys4
12
CaMKII
12
phosphoenolpyruvate carboxykinase
12
phenylethanolamine N-methyltransferase
12
beta-galactosidase
11
phosphoinositide 3-kinase
11
furin
11
sucrase
11
GRK5
10
glyceraldehyde-3-phosphate dehydrogenase
10
more...
Compound
glucose
2661
Clin
1572
Dec
1538
calcium
1059
cAMP
694
arginine
571
Octreotide
560
Insulin
545
tyrosine
530
GABA
487
GABA
481
DNA
445
Phe
432
lysine
425
ACTH
422
sodium
413
TSH
381
TRH
355
AMP
334
water
326
glutamate
319
threonine
300
Glucagon
297
NH2
273
leucine
264
acetate
259
potassium
258
5-HT
254
noradrenaline
245
methionine
242
alanine
235
gamma-aminobutyric acid
220
Substance P
213
DTPA
187
GTP
164
His
163
nitric oxide
162
silver
150
phosphate
149
ATP
147
ethanol
142
Diabetol
116
galactose
109
Dopamine
104
acetic acid
102
iodine
101
glycerol
100
oxygen
98
Gly
97
Ile
92
Calcitonin
81
HCl
80
isoleucine
77
isoleucine
76
Cysteamine
75
Secretin
75
Thyroid
74
ACh
73
Adrenal
73
Neurotensin
73
sulfate
71
cGMP
70
Atropine
69
salt
69
NMDA
69
tryptophan
66
L-DOPA
65
Cereb
64
ADP
63
Forskolin
63
hydroxyindoleacetic acid
62
ADP
62
nitrogen
61
serine
61
alloxan
61
Neuronal
61
cysteine
61
ADP
61
urea
59
tryptophan
59
more...