Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P61278 (somatostatin)
 22,083 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report on a patient with connatal chronic diarrhea. Electron microscopical examination revealed "microvillus inclusion disease", characterized by enterocyte brushborder abnormalities. Differential diagnoses are enteral infection and intolerance to formula protein, rarely disaccharidase deficiency. Therapeutic approaches with glucocorticosteroids, pentagastrin and somatostatin failed, just as using growth factor did. No differentiation of the enterocytes occurred with increasing age. Altogether the prognosis of this disease is very poor.
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PMID:[Congenital villous atrophy. Disease picture of congenital chronic diarrhea with poor prognosis]. 811 73