Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P61278 (
somatostatin
)
22,083
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The influence of
somatostatin
on tumor cell growth was studied in vivo in mice (
sarcoma 180
ascites tumor and Lewis lung tumor) and in vitro on nontransformed and polyoma-transformed cell lines. 4 or 20 micrograms/100 g of cyclic
somatostatin
and 4 micrograms/100 g of linear protamin Zn-bound
somatostatin
were injected s.c. twice daily in the in vivo study. Cyclic
somatostatin
(1, 4 or 10 micrograms/ml) was added twice daily to the cell cultures.
Somatostatin
administration influenced neither the survival of animals nor the growth rate of cultured cell lines.
...
PMID:Failure of somatostatin to influence experimental tumor cell growth in vivo and in vitro. 611 74
