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Query: UNIPROT:P56851 (epididymal)
 11,273 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We reviewed the records of 34 patients with epididymal and/or testicular abscess that were treated at our institution. The mean age of the patients was 48.6 years. The most common clinical manifestation was scrotal pain. The diagnosis was made on the clinical and/or scrotal ultrasound findings. E. coli was isolated in 84.6% of the cases. Chronic and acute orchitis with abscess formation were the most common histological findings. Twenty-nine cases required antibiotic therapy plus surgery and five cases required antibiotics alone.
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PMID:[Epididymo-testicular abscess]. 794 95

With the aim of describe a typology that will result in a more precise diagnostic which in turn will permit the selection of the most direct method approach, an analysis was made of the clinical characteristics of patients we treated due to the presence of torsion of the testicular and epididymal appendages. A retrospective review was made of 91 patients, taking into account this age, time of appearance, time of evolution, symptoms, physical examination, histological study and effects. The average age was 9.47 years with a greater incidence occurring between the eight and twelve years old. No influence due to a seasonal phase was detected. The time span between the initial appearance of the symptoms and the time of admittance was 39.5 hours, being somewhat less in patients below the age of six. The common symptom was pain. In addition, 58.2% of the patients also suffered scrotal affectation. In 31 patients the hydatid was palpable and in 19 the "blue dot sign" rendered positive. In 83 cases, surgery was done via the scrotum, resulting in the confirmation of the initial diagnosis. The affectation of the left side was more frequent (62.5%). The hospital discharge was possible in less than 48 hours with no visible long-term effects. Thus, we believe that it is possible to almost always make a diagnosis based on the clinical data, and the type of treatment to be applied should be the extirpation of the hydatid to be carried out via the scrotum.
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PMID:[The clinical characteristics of patients with torsion of the testicular and epididymal appendages]. 799 19

The current trend in South African health services is toward primary care. Pulmonary tuberculosis is well understood by the majority of primary care doctors and nurses, whereas genito-urinary tuberculosis may not be as easy to diagnose and treat. We reviewed our experience with this condition in 52 patients, who represented 0.74% of urology admissions between 1986 and 1991. There was a 3:2 male/female ratio, the age range was 7-76 years (mean 43 years), and the disease was more common among blacks and coloureds than among whites. Multiple sites of involvement were fairly common. Seventy-five per cent of patients had renal involvement and 17% epididymal involvement. The commonest presenting complaints were urinary frequency and haematuria, although flank and scortal pain were also reported by a number of patients. Physical examination seldom helped to suggest the diagnosis. On microscopic examination and culture of the urine, sterile pyuria was present in only 50% of our patients and 29% had positive cultures for a 'normal' coliform organism. Fifty patients underwent excretory urography and the findings were very varied. Patients were treated primarily with antituberculosis drugs, but 58% also required some form of surgery; nephrectomy was the commonest operation. Ureteral strictures developed in over 50% of cases with renal involvement. We conclude that the diagnosis of genito-urinary tuberculosis is not simple, and that treatment must include regular follow-up at a specialist institution.
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PMID:Genito-urinary tuberculosis--experience with 52 urology inpatients. 811 17

Vasectomy is the most reliable method of birth control. More than 33 million couples now rely on it in the United States, the United Kingdom, India, China, Thailand, South Korea, Canada, the Netherlands, and New Zealand. Many of the problems associated with vasectomy can be prevented by discussion about the procedure beforehand with the couple concerned, with clear warning that complications can sometimes occur. Recently, a no-scalpel technique has been introduced by Dr Li Shunqiang in China with good results. During 10 and 12 weeks follow-up, semen should be examined. The detailed study of 1000 vasectomies performed under local anesthetic at the Margaret Pyke Centre in London defined the expected complication rate. Two patients suffered vasovagal attacks during the operation and required resuscitation. Minor hematomas occurred in 3.5%. 12 developed minor sepsis but only one abscess occurred. Three cases of epididymo-orchitis were seen. Altogether, 5.6% of patients complained of minor local symptoms including bruising. In the large Oxford Series, 7.7% sought medical advice for local pain and 3.6% for bleeding. Scrotal hematoma developed in 0.9%. 80% returned to work in 3 days and 96% within 1 week. Spermatozoa have been found in a para-aortic lymph node one year after vasectomy in a man undergoing laparotomy, and circulating antisperm antibodies can be detected by sperm-agglutination tests in the serum of 60-80% of men following vasectomy. Technical difficulties with vas anastomosis and secondary changes in the epididymis make the chances of successful restoration of fertility only a little better than 50%. There are four causes of failure of vasectomy reversal: 1) in about half of patients there is stenosis or blockage of the previous vaso-vasostomy, 2) the second most common cause is epididymal blockage, 3) development of a very high antisperm antibody response to the vasectomy, and 4) cessation of spermatogenesis.
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PMID:Vasectomy and vasectomy reversal. 819 17

Congenital prostatic cysts are relatively uncommon and rarely symptomatic. We describe a 24-year-old man who presented with a 2-month history of anejaculation accompanied with bilateral epididymal pain. Transrectal ultrasonography of the prostate revealed a large midline prostatic cyst and bilateral dilatation of the seminal vesicles. Transrectal aspiration of the cyst resulted in return of antegrade ejaculation and resolution of epididymal pain.
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PMID:Congenital prostatic cyst causing ejaculatory duct obstruction: management by transrectal cyst aspiration. 848 34

Following vasectomy, spermatogenesis continues, the human epididymis and ductus deferens may distend and leak, and the extravasated spermatozoa stimulate formation of a sperm granuloma. Granulomas may occur at 60% of vasectomy sites and are usually asymptomatic and relieve intraluminal pressure. About 3-5% of patients experience pain. Intraluminal phagocytosis may explain why some reproductive tracts become depleted of spermatozoa. Distension of the epididymis is common after vasectomy and may lead to granuloma formation there. Up to 6% of patients have symptoms, but many with epididymal changes have no discomfort. Most episodes of painful epididymitis and granulomas resolve with conservative treatment, but < 1% require vasectomy reversal or, if this is ineffective, excision of the epididymis and obstructed ductus deferens.
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PMID:Vasectomy review: sequelae in the human epididymis and ductus deferens. 884 41

Ultrasound is the most sensitive imaging method available for demonstration of the scrotal contents. The main indications for the use of ultrasound are scrotal masses and pain. Solid intratesticular masses are typically malignant, whereas solid epididymal masses are usually benign.
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PMID:Scrotal ultrasound. 902 16

The authors report the case of a 3-year-old child with tuberculous epididymo-orchitis. The only presenting symptom was testicular, epididymis and scrotal swelling and pain. Diagnosis was reached after histopathological examination of epididymis and testis tissues. The response to antitubercular drugs given with prednisolone was rapid. This case emphasizes the importance of considering tuberculosis in differential diagnosis of testicular and epididymal enlargement in young children in an endemic area despite the absence of systemic, pulmonary and urinary manifestations.
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PMID:A 3-year-old boy with tuberculous epididymo-orchitis. 903 25

A 70-year-old male was hospitalized for right scrotal mass without pain in October 1991. Right orchiectomy was performed under a diagnosis of right epididymal tumor. Histopathological diagnosis was testicular adenomatoid tumor. In June 1992, he was admitted with a mass in the right inguinal region and a tumor was resected. Histopathological diagnosis was malignant testicular mesothelioma. Therefore, retroperitoneal lymphadenectomy was performed as additional therapy. One year after surgery he showed signs of recurrence and was admitted for treatment and further examination. Computed tomography demonstrated right inguinal and femoral mass. Thus he underwent total penectomy and radical ilioinguinal lymphadenectomy under a diagnosis of metastatic and recurrent mesothelioma of the testis. Three months postoperatively he developed a recurrence in the skin and lung field. After combination chemotherapy, the metastatic skin lesion was in remission but the lung lesion did not respond. Metastatic lung tumor grew rapidly and the patient died. The incidence of malignant mesothelioma of the tunica vaginalis testis is rare and 48 cases have been reported in the literature.
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PMID:[A case of malignant mesothelioma associated intrascrotal mass]. 912 70

A total of 37 percutaneous epididymal sperm aspiration (PESA) and/or testicular sperm aspiration (TESA) procedures were performed under local anaesthesia (LA) on 34 men between June and November 1996. Local anaesthesia was achieved by injecting 10 ml of 1% lignocaine solution along the sides of the vas deferens near the external inguinal ring (spermatic cord block). Sperm retrieval was successful in 92% of the procedures. Of the 37 procedures, in 29 the patients felt either no pain or mild discomfort while in six they experienced moderate but tolerable pain. Analgesia was incomplete in two procedures and was supplemented with i.v. sedation. Vasovagal reflex in two procedures was reversed by i.v. atropine. In 24 procedures patients felt relaxed, whilst in 13 they felt anxious. In 32 procedures the patients expressed overall satisfaction. If the procedure was to be repeated, after 29 procedures the patients requested LA again, while after four procedures they preferred i.v. sedation and after four were undecided. LA is adequate for PESA and TESA in a large proportion of patients. Prior discussion of LA technique with the patient is necessary. Back-up facilities for i.v. sedation and atropine should be available.
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PMID:The efficacy of local anaesthesia for percutaneous epididymal sperm aspiration and testicular sperm aspiration. 957 27


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