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Query: UNIPROT:P56851 (epididymal)
 11,273 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of epididymotesticular metastases are reported: one epididymal from a carcinoma of the kidney by retrograde venous spread and the other testicular secondary to a carcinoma of the prostate and apparently by arterial spread. Epididymotesticular metastases of carcinomas are rare. When the initial carcinoma is known, or even treated, the development of a large testis should lead to consideration of the possibility. Treatment should consist of inguinal orchidectomy with ligation of the spermatic cord as high as possible.
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PMID:[Epididymal and testicular metastases. 2 cases (author's transl)]. 49 14

A case of epididymal metastasis from carcinoma of the prostate with an unusual presentation is reported. A review of the literature disclosed only 10 reported cases of this rare finding. A mechanism for the method of metastasis in this patient is proposed.
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PMID:Epididymal metastasis from prostatic carcinoma. 403 47

A retrospective study was done on 185 patients who underwent transurethral prostatectomy. Of these patients 6 had seminal vesicle tissue in the resected specimen. The presence of the yellow-brown pigment, lipofuscin, in the seminal vesicle epithelium was a consistent finding and, often, paramount to differentiation from carcinoma of the prostate. There was no pathological misdiagnosis of malignancy in this series. Of the 6 patients 2 suffered acute epididymitis postoperatively and 1 had persistent microscopic hematuria 2 months postoperatively. The high incidence of postoperative epididymitis probably is owing to contamination of the seminal vesicles by bacteria. Acquired during urinary tract manipulation, having access to the seminal vesicles and, thus, the vas deferens. In these patients vasectomy and broad-spectrum antibiotics are recommended because epididymal invasion by bacteria may already have occurred before pathologic diagnosis is obtained.
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PMID:Transurethral resection of the prostate with partial resection of the seminal vesicle. 729 20

Tissue testosterone, dihydrotestosterone, and zinc concentrations have been determined in testis and epididymis of 13 patients with carcinoma of the prostate, 1 patient with carcinoma of the penis, and 3 patients with carcinoma of the prostate on estrogens. The 13 patients not receiving estrogens had the following testicular levels: testosterone, of 529 +/- 63.1 ng/g (mean +/- SE); dihydrotestosterone, 23.7 +/- 2.58 ng/g; and zinc 62.2 +/- 7.6 micrograms/g. The epididymal levels were as follows: testosterone, 40.6 +/- 3.4 ng/g; dihydrotestosterone, 20.5 +/- 2.36 ng/g; and zinc, 67.2 +/- 11.1 micrograms/g. Patients on estrogen therapy showed much lower androgen values in the two organs but zinc was not changed significantly. Concentrations of androgens were not significantly different in the epididymal fractions of caput, corpus, and cauda. In testis, there was a positive correlation between zinc and androgens contents, while the opposite was suggested by the data in the epididymis. Even though these patients were not normal, there was no evidence of testicular or epididymal disturbances.
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PMID:Testosterone, dihydrotestosterone, and zinc concentrations in human testis and epididymis. 731 3

Epididymal Metastasis from a primary carcinoma of the prostate gland is a rare but recognised phenomena. We describe a case of such metastasis which, unlike previous reports, presents as a painful epididymal mass. Therefore it is important for urologists to consider epididymal metastasis as part of the differential diagnosis in a patient with known carcinoma of the prostate and a tender epididymal mass.
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PMID:Epididymal metastasis from carcinoma of the prostate. 1534 41

Carcinoma prostate secondary metastasis to testicle and epididymis is rare. We report a case of metastatic carcinoma prostate in which testicular and epididymal metastasis were diagnosed incidentally in bilateral orchiectomy specimen. Testicular and para testicular structure should be properly evaluated for accurate staging of carcinoma prostate. Epididymis should always be included in bilateral orchidectomy specimen.
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PMID:Testicular and Epididymal Metastasis from Prostate Carcinoma: A Rare Manifestation of Common Disease. 2920 73