Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P56851 (epididymal)
 11,273 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 54-year-old Canadian presented with a 1-month history of painless swelling in the right testis. The diagnosis was thought to be a sperm granuloma, a leiomyoma, or an adenomatoid tumour of the epididymis; histologic examination, however, revealed evidence of schistosomiasis, probably due to Schistosoma haematobium. Solitary schistosomiasis of the epididymis has been reported previously in only two cases. Epididymal schistosomiasis has never been diagnosed preoperatively because it is so rare, but even if it were suspected preoperatively and confirmed by biopsy, chemotherapy alone would not prevent impairment of epididymal function due to scarring. Surgical excision of the lesion, therefore, is recommended.
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PMID:Solitary epididymal schistosomiasis. 117 14

The authors report on two isolated cases of bilharzioma: one vesical revealed by an hematuria and one epididymal constituting an intrascrotal mass. Clinical signs did not oriented toward these diagnosis and biology was helpless. Serodiagnosis by hemagglutination was negative, but immunofluorescence was more reliable. On the contrary both tumors were detected by echotomography of which the efficiency is determinant for the diagnosis and must be underlined. Only anatomopathology was able to confirm the diagnosis of tumor. As a matter of course, surgical exploration and excision are necessary in these types of tumors with negative biology. In both cases, effects were isolated. In one patient, infestation was old and already treated; in the second one, infestation was probably light. The authors recall also bilharzioma physiopathology. Frequency of vesical bilharzioma is about 20% of genito-urinary schistosomiasis while epididymal bilharzioma reaches only 0.29 to 4.8%. Direct line between bilharzioma and cancer is likely but controversial, schistosomiasis beeing a true irritative agent.
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PMID:[Genitourinary bilharzioma. Isolated cases of vesical bilharzioma and epididymal bilharzioma]. 393 97