Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P52742 (
pT3
)
1,034
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The aim of the present study was to evaluate the activity of
cathepsin B
in 36 colorectal adenocarcinomas at stage
pT3
of clinical advancement and histological grade G2. A correlation was also analysed of
cathepsin B
activity with the stage of anatomo-clinical advancement and the presence of chosen anatomo-clinical features of the tumour. Statistically significantly higher activity of
cathepsin B
was observed both in the cytosol and homogenate of the neoplastic tissue compared to its activity in the cytosol and homogenate of the adjacent unchanged tissue. A tendency was found towards higher
cathepsin B
activity in homogenate than in cytosol, both in the neoplastic and normal tissue. No correlation was revealed between
cathepsin B
activity in neoplastic cells and other anatomo-clinical tumour parameters analysed.
...
PMID:[The activity of cathepsin B in colorectal adenocarcinomas]. 1177 Mar 13
