Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P51812 (mitogen-activated protein)
10,636 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein mitogen-activated protein 10636 p38 3522 MAP kinase 2022 ERK1 1536 extracellular signal-regulated kinase 1332 Mol 1330 JNK 1174 ERK 1085 c-Jun 969 MEK 865 cytokine 801 Sep 750 MAPK 726 tumor necrosis factor 695 lipopolysaccharide 661 p38 MAP kinase 654 p42 617 p44 550 ERK2 500 IL-6 440 tyrosine kinase 410 caspase-3 397 TNF 396 phosphatidylinositol 3-kinase 394 insulin 378 MEK1 353 inducible nitric oxide synthase 347 AP-1 336 epidermal growth factor 320 threonine 317 cyclooxygenase-2 314 phosphatase 311 extracellular signal-regulated kinase 1 302 Bcl-2 258 IL-8 234 p65 232 interleukin-6 231 collagen 220 TLR4 219 MAP 218 TNF-alpha 216 protein kinase B 215 JNK1 204 p53 200 c-fos 199 nitric oxide synthase 195 angiotensin II 192 ATP 192 AKT 191 Raf-1 190 epidermal growth factor receptor 182 LPS 172 tumor necrosis factor alpha 165 p21 163 platelet-derived growth factor 163 vascular endothelial growth factor 151 matrix metalloproteinase 148 PKC 148 Rho 148 chemokine 147 phosphoinositide 3-kinase 142 interferon 142 AMP 141 Ang II 140 heme oxygenase-1 132 COX-2 128 PI3K 126 calmodulin 124 mTOR 123 IL-10 123 superoxide dismutase 122 nerve growth factor 120 myelin basic protein 119 erythroid 117 cytochrome c 116 cyclin 115 MEKK 114 cyclooxygenase 112 GTP 110 catalase 109 more...

Disease cancer 991 tumor 593 pertussis 202 diabetes 202 ischemia 192 breast cancer 179 atherosclerosis 164 hypertension 148 tumorigenesis 144 carcinogenesis 137 Alzheimer's disease 133 leukemia 120 carcinoma 118 hepatocellular carcinoma 117 melanoma 111 tumor growth 110 rheumatoid arthritis 97 neuroblastoma 90 MCF 89 prostate cancer 86 asthma 84 GSH 77 obesity 75 sepsis 73 tumor progression 73 sepsis 72 Parkinson's disease 67 arthritis 65 heart failure 63 stroke 61 pheochromocytoma 60 colon cancer 60 lung cancer 55 adenocarcinoma 53 infectious diseases 51 osteoarthritis 49 Blocking 49 HIV 49 colorectal cancer 46 glioma 46 cold 44 virus infection 44 depression 44 ATM 44 cardiovascular disease 44 Mycobacterium 44 colitis 43 osteoporosis 42 lymphoma 41 chronic obstructive pulmonary disease 41 hyperglycemia 40 Infection 39 cerebral ischemia 38 type 2 diabetes 38 metastases 38 SDS 37 inflammatory bowel disease 37 myocardial infarction 35 squamous cell carcinoma 34 B-cell lymphoma 34 retinoblastoma 33 tuberculosis 32 gastric cancer 32 skin cancer 31 immunodeficiency 31 bacterial infection 29 multiple sclerosis 29 ovarian cancer 28 pancreatic cancer 28 lung carcinoma 28 diabetic nephropathy 27 osteosarcoma 27 renal disease 27 glioblastoma 26 astrocytoma 26 multiple myeloma 26 acute myeloid leukemia 24 myocardial ischemia 24 chronic myeloid leukemia 24 dermatitis 23 more...

Symptom pain 94 starvation 32 seizures 28 diarrhea 19 anesthesia 12 collapse 10 skin damage 10 vomiting 9 erythema 9 functional recovery 9 hyperoxia 9 analgesia 7 respiratory distress 7 headache 6 splenomegaly 5 cachexia 5 arthralgia 5 acute stress 5 fatigue 4 cough 4 Neuropathic pain 4 anorexia 3 Ear swelling 3 nausea 3 acute pain 3 weakness 3 dry eye 2 exhaustion 2 tremor 2 orofacial pain 2 stigma 2 ataxia 2 dental pain 2 dyspnea 2 neuralgia 2 scaly skin 2 constipation 2 pelvic pain 2 hypothermia 2 angina 2 bone pain 2 chronic cough 2 low back pain 2 Macula 1 ENT 1 dysuria 1 memory loss 1 paresis 1 swollen joints 1 paresthesia 1 fasciculation 1 spasm 1 tinnitus 1 neck pain 1 cancer pain 1 muscle cramps 1 flushing 1 acidity 1 chills 1 abdominal pain 1 hepatosplenomegaly 1 hypotonia 1 Organ failure 1 back pain 1 nausea and vomiting 1 night sweats 1 overweight 1 skin irritation 1 muscle stiffness 1 skin irritant 1 menopausal symptoms 1 hypercapnia 1 ataxic gait 1 Inflammatory pain 1 twitching 1 sore throat 1 Decreased activity 1 thinning 1 catarrh 1 autodigestion 1 more...

Drug MAP 228 Angiotensin II 66 ROS 64 IFN-gamma 59 IL-2 56 Dermatol 47 Cardiovasc 44 CSF 38 lysine 29 ETS 25 ICI 24 Ethanol 22 Heme 21 vitamin E 20 p75 20 Forskolin 18 caffeine 18 Gel 16 EE2 15 TAK 15 ETA 14 Histamine 13 ascorbate 13 Taxol 12 IFN-beta 11 Arsenic trioxide 11 Epigallocatechin 9 Retinoic acid 9 NADH 8 Gefitinib 8 Glycyrrhiza 8 Activin 8 Monit 7 Sorafenib 7 IL-11 7 Growth hormone 7 ABC 7 Ouabain 7 Simvastatin 7 Growth hormone 7 PTH 7 Nephron 7 Gelatin 6 Nitric Oxide 6 Asn 6 MRC 6 Emodin 5 Sodium nitroprusside 5 Emodin 5 CoCl2 5 Indomethacin 5 GRF 5 Myricetin 5 Cetuximab 5 Glutathione 5 Ginseng 5 CoCl2 5 Estrogens 4 Leaf 4 Mutagen 4 CCL 4 EPA 4 Rolipram 4 PCP 4 Imatinib 4 TAT 4 Silica 4 Glucagon 4 Albumin 4 Glycerol 3 NBT 3 Portal 3 DNase I 3 K-252a 3 Gleevec 3 Asthma 3 Nexavar 3 Flavopiridol 3 Oxaliplatin 3 Rutin 3 more...

Enzyme mitogen-activated protein kinase 6382 protein kinase 1321 ERK 1283 MEK 1274 protein kinase C 894 phosphatidylinositol 3-kinase 395 caspase-3 325 focal adhesion kinase 258 MAP 218 phospholipase C 201 NO synthase 156 MEKK1 155 calcineurin 150 luciferase 143 phosphoinositide 3-kinase 142 NADPH oxidase 137 superoxide dismutase 133 catalase 118 NADPH oxidase 117 collagenase 90 phospholipase A2 89 IKK 89 thrombin 85 peroxidase 80 cdc2 77 PARP 75 proteasome 70 glutathione peroxidase 67 ATPase 65 caspase-9 64 glutathione S-transferase 62 AMP-activated protein kinase 60 AMPK 57 alkaline phosphatase 56 renin 53 caspase-8 51 CaMKII 50 GSK 47 heme oxygenase 46 adenylate cyclase 44 lactate dehydrogenase 44 phospholipase D 43 MMP-3 38 protein phosphatase 2A 36 reverse transcriptase 34 RNA polymerase 33 guanylate cyclase 31 alanine aminotransferase 30 caspase-1 29 urokinase-type plasminogen activator 28 aspartate aminotransferase 26 phosphodiesterase 24 trypsin 24 myosin light chain kinase 24 tyrosinase 22 MIP 22 lipoxygenase 22 tyrosine hydroxylase 22 MMP 21 NOS 19 xanthine oxidase 18 ornithine decarboxylase 18 cathepsin K 18 NQO1 16 AMPK 15 transcriptase 15 PKG 14 hexosaminidase 14 lipase 13 elastase 13 glutathione reductase 13 sphingosine kinase 13 APC 13 creatine kinase 12 GRK2 12 PDK1 12 acetylcholinesterase 11 acetyl-CoA carboxylase 11 PTPase 11 ACS 10 more...

Compound tyrosine 1075 oxygen 976 DNA 969 Dec 832 calcium 712 MEK 572 nitric oxide 559 threonine 431 serine 419 TNF 396 acetate 371 cAMP 309 glucose 270 NH2 229 MAP 218 ATP 193 sodium 187 cysteine 182 phosphate 182 hydrogen 178 Clin 165 AMP 147 water 145 H2O2 122 glutamate 122 PGE 121 GTP 110 alanine 98 Ang II 96 THP 94 THP 94 N-acetylcysteine 94 ethanol 93 Insulin 92 MTT 92 arginine 80 GSH 79 GSH 79 Angiotensin II 78 leucine 77 nitrogen 73 Phe 72 PMA 71 proline 69 salicylic acid 68 MDA 68 PMA 68 galactose 67 COS 67 sulfate 63 glycerol 61 salt 61 lysine 57 cGMP 56 Cardiol 49 ATF 49 ADP 49 retinoic acid 48 bromide 47 zinc 46 potassium 46 Asp 46 dUTP 44 methionine 42 Wortmannin 42 cadmium 42 ADP 41 iodine 41 ADP 41 Curcumin 38 SDS 37 CO2 34 iron 33 nicotinamide 31 Phosphatidylinositol 31 PGE2 30 NADPH 29 ADP-ribose 29 NADPH 29 diacetate 29 more...

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