Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P51812 (
mitogen-activated protein
)
10,636
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mitogen-activated protein
10636
p38
3522
MAP kinase
2022
ERK1
1536
extracellular signal-regulated kinase
1332
Mol
1330
JNK
1174
ERK
1085
c-Jun
969
MEK
865
cytokine
801
Sep
750
MAPK
726
tumor necrosis factor
695
lipopolysaccharide
661
p38 MAP kinase
654
p42
617
p44
550
ERK2
500
IL-6
440
tyrosine kinase
410
caspase-3
397
TNF
396
phosphatidylinositol 3-kinase
394
insulin
378
MEK1
353
inducible nitric oxide synthase
347
AP-1
336
epidermal growth factor
320
threonine
317
cyclooxygenase-2
314
phosphatase
311
extracellular signal-regulated kinase 1
302
Bcl-2
258
IL-8
234
p65
232
interleukin-6
231
collagen
220
TLR4
219
MAP
218
more...
Disease
cancer
991
tumor
593
pertussis
202
diabetes
202
ischemia
192
breast cancer
179
atherosclerosis
164
hypertension
148
tumorigenesis
144
carcinogenesis
137
Alzheimer's disease
133
leukemia
120
carcinoma
118
hepatocellular carcinoma
117
melanoma
111
tumor growth
110
rheumatoid arthritis
97
neuroblastoma
90
MCF
89
prostate cancer
86
asthma
84
GSH
77
obesity
75
sepsis
73
tumor progression
73
sepsis
72
Parkinson's disease
67
arthritis
65
heart failure
63
stroke
61
colon cancer
60
pheochromocytoma
60
lung cancer
55
adenocarcinoma
53
infectious diseases
51
HIV
49
Blocking
49
osteoarthritis
49
colorectal cancer
46
glioma
46
more...
Symptom
pain
94
starvation
32
seizures
28
diarrhea
19
anesthesia
12
skin damage
10
collapse
10
erythema
9
functional recovery
9
vomiting
9
hyperoxia
9
analgesia
7
respiratory distress
7
headache
6
cachexia
5
acute stress
5
splenomegaly
5
arthralgia
5
cough
4
fatigue
4
Neuropathic pain
4
Ear swelling
3
anorexia
3
acute pain
3
weakness
3
nausea
3
exhaustion
2
dry eye
2
hypothermia
2
constipation
2
neuralgia
2
dyspnea
2
chronic cough
2
ataxia
2
dental pain
2
scaly skin
2
tremor
2
stigma
2
angina
2
pelvic pain
2
more...
Drug
MAP
228
Angiotensin II
66
ROS
64
IFN-gamma
59
IL-2
56
Dermatol
47
Cardiovasc
44
CSF
38
lysine
29
ETS
25
ICI
24
Ethanol
22
Heme
21
vitamin E
20
p75
20
Forskolin
18
caffeine
18
Gel
16
EE2
15
TAK
15
ETA
14
ascorbate
13
Histamine
13
Taxol
12
Arsenic trioxide
11
IFN-beta
11
Epigallocatechin
9
Retinoic acid
9
Activin
8
NADH
8
Glycyrrhiza
8
Gefitinib
8
ABC
7
Monit
7
IL-11
7
Growth hormone
7
PTH
7
Ouabain
7
Growth hormone
7
Simvastatin
7
more...
Enzyme
mitogen-activated protein kinase
6382
protein kinase
1321
ERK
1283
MEK
1274
protein kinase C
894
phosphatidylinositol 3-kinase
395
caspase-3
325
focal adhesion kinase
258
MAP
218
phospholipase C
201
NO synthase
156
MEKK1
155
calcineurin
150
luciferase
143
phosphoinositide 3-kinase
142
NADPH oxidase
137
superoxide dismutase
133
catalase
118
NADPH oxidase
117
collagenase
90
phospholipase A2
89
IKK
89
thrombin
85
peroxidase
80
cdc2
77
PARP
75
proteasome
70
glutathione peroxidase
67
ATPase
65
caspase-9
64
glutathione S-transferase
62
AMP-activated protein kinase
60
AMPK
57
alkaline phosphatase
56
renin
53
caspase-8
51
CaMKII
50
GSK
47
heme oxygenase
46
lactate dehydrogenase
44
more...
Compound
tyrosine
1075
oxygen
976
DNA
969
Dec
832
calcium
712
MEK
572
nitric oxide
559
threonine
431
serine
419
TNF
396
acetate
371
cAMP
309
glucose
270
NH2
229
MAP
218
ATP
193
sodium
187
cysteine
182
phosphate
182
hydrogen
178
Clin
165
AMP
147
water
145
glutamate
122
H2O2
122
PGE
121
GTP
110
alanine
98
Ang II
96
THP
94
N-acetylcysteine
94
THP
94
ethanol
93
MTT
92
Insulin
92
arginine
80
GSH
79
GSH
79
Angiotensin II
78
leucine
77
more...