Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P51812 (mitogen-activated protein)
10,636 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mitogen-activated protein 10636
p38 3522
MAP kinase 2022
ERK1 1536
extracellular signal-regulated kinase 1332
Mol 1330
JNK 1174
ERK 1085
c-Jun 969
MEK 865
cytokine 801
Sep 750
MAPK 726
tumor necrosis factor 695
lipopolysaccharide 661
p38 MAP kinase 654
p42 617
p44 550
ERK2 500
IL-6 440
tyrosine kinase 410
caspase-3 397
TNF 396
phosphatidylinositol 3-kinase 394
insulin 378
MEK1 353
inducible nitric oxide synthase 347
AP-1 336
epidermal growth factor 320
threonine 317
cyclooxygenase-2 314
phosphatase 311
extracellular signal-regulated kinase 1 302
Bcl-2 258
IL-8 234
p65 232
interleukin-6 231
collagen 220
TLR4 219
MAP 218
more...
Disease
cancer 991
tumor 593
pertussis 202
diabetes 202
ischemia 192
breast cancer 179
atherosclerosis 164
hypertension 148
tumorigenesis 144
carcinogenesis 137
Alzheimer's disease 133
leukemia 120
carcinoma 118
hepatocellular carcinoma 117
melanoma 111
tumor growth 110
rheumatoid arthritis 97
neuroblastoma 90
MCF 89
prostate cancer 86
asthma 84
GSH 77
obesity 75
sepsis 73
tumor progression 73
sepsis 72
Parkinson's disease 67
arthritis 65
heart failure 63
stroke 61
colon cancer 60
pheochromocytoma 60
lung cancer 55
adenocarcinoma 53
infectious diseases 51
HIV 49
Blocking 49
osteoarthritis 49
colorectal cancer 46
glioma 46
more...
Symptom
pain 94
starvation 32
seizures 28
diarrhea 19
anesthesia 12
skin damage 10
collapse 10
erythema 9
functional recovery 9
vomiting 9
hyperoxia 9
analgesia 7
respiratory distress 7
headache 6
cachexia 5
acute stress 5
splenomegaly 5
arthralgia 5
cough 4
fatigue 4
Neuropathic pain 4
Ear swelling 3
anorexia 3
acute pain 3
weakness 3
nausea 3
exhaustion 2
dry eye 2
hypothermia 2
constipation 2
neuralgia 2
dyspnea 2
chronic cough 2
ataxia 2
dental pain 2
scaly skin 2
tremor 2
stigma 2
angina 2
pelvic pain 2
more...
Drug
MAP 228
Angiotensin II 66
ROS 64
IFN-gamma 59
IL-2 56
Dermatol 47
Cardiovasc 44
CSF 38
lysine 29
ETS 25
ICI 24
Ethanol 22
Heme 21
vitamin E 20
p75 20
Forskolin 18
caffeine 18
Gel 16
EE2 15
TAK 15
ETA 14
ascorbate 13
Histamine 13
Taxol 12
Arsenic trioxide 11
IFN-beta 11
Epigallocatechin 9
Retinoic acid 9
Activin 8
NADH 8
Glycyrrhiza 8
Gefitinib 8
ABC 7
Monit 7
IL-11 7
Growth hormone 7
PTH 7
Ouabain 7
Growth hormone 7
Simvastatin 7
more...
Enzyme
mitogen-activated protein kinase 6382
protein kinase 1321
ERK 1283
MEK 1274
protein kinase C 894
phosphatidylinositol 3-kinase 395
caspase-3 325
focal adhesion kinase 258
MAP 218
phospholipase C 201
NO synthase 156
MEKK1 155
calcineurin 150
luciferase 143
phosphoinositide 3-kinase 142
NADPH oxidase 137
superoxide dismutase 133
catalase 118
NADPH oxidase 117
collagenase 90
phospholipase A2 89
IKK 89
thrombin 85
peroxidase 80
cdc2 77
PARP 75
proteasome 70
glutathione peroxidase 67
ATPase 65
caspase-9 64
glutathione S-transferase 62
AMP-activated protein kinase 60
AMPK 57
alkaline phosphatase 56
renin 53
caspase-8 51
CaMKII 50
GSK 47
heme oxygenase 46
lactate dehydrogenase 44
more...
Compound
tyrosine 1075
oxygen 976
DNA 969
Dec 832
calcium 712
MEK 572
nitric oxide 559
threonine 431
serine 419
TNF 396
acetate 371
cAMP 309
glucose 270
NH2 229
MAP 218
ATP 193
sodium 187
cysteine 182
phosphate 182
hydrogen 178
Clin 165
AMP 147
water 145
glutamate 122
H2O2 122
PGE 121
GTP 110
alanine 98
Ang II 96
THP 94
N-acetylcysteine 94
THP 94
ethanol 93
MTT 92
Insulin 92
arginine 80
GSH 79
GSH 79
Angiotensin II 78
leucine 77
more...