Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P51812 (
mitogen-activated protein
)
10,636
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mitogen-activated protein
10636
p38
3522
MAP kinase
2022
ERK1
1536
extracellular signal-regulated kinase
1332
Mol
1330
JNK
1174
ERK
1085
c-Jun
969
MEK
865
cytokine
801
Sep
750
MAPK
726
tumor necrosis factor
695
lipopolysaccharide
661
p38 MAP kinase
654
p42
617
p44
550
ERK2
500
IL-6
440
more...
Disease
cancer
991
tumor
593
diabetes
202
pertussis
202
ischemia
192
breast cancer
179
atherosclerosis
164
hypertension
148
tumorigenesis
144
carcinogenesis
137
Alzheimer's disease
133
leukemia
120
carcinoma
118
hepatocellular carcinoma
117
melanoma
111
tumor growth
110
rheumatoid arthritis
97
neuroblastoma
90
MCF
89
prostate cancer
86
more...
Symptom
pain
94
starvation
32
seizures
28
diarrhea
19
anesthesia
12
collapse
10
skin damage
10
erythema
9
vomiting
9
hyperoxia
9
functional recovery
9
respiratory distress
7
analgesia
7
headache
6
acute stress
5
arthralgia
5
splenomegaly
5
cachexia
5
fatigue
4
cough
4
more...
Drug
MAP
228
Angiotensin II
66
ROS
64
IFN-gamma
59
IL-2
56
Dermatol
47
Cardiovasc
44
CSF
38
lysine
29
ETS
25
ICI
24
Ethanol
22
Heme
21
p75
20
vitamin E
20
caffeine
18
Forskolin
18
Gel
16
TAK
15
EE2
15
more...
Enzyme
mitogen-activated protein kinase
6382
protein kinase
1321
ERK
1283
MEK
1274
protein kinase C
894
phosphatidylinositol 3-kinase
395
caspase-3
325
focal adhesion kinase
258
MAP
218
phospholipase C
201
NO synthase
156
MEKK1
155
calcineurin
150
luciferase
143
phosphoinositide 3-kinase
142
NADPH oxidase
137
superoxide dismutase
133
catalase
118
NADPH oxidase
117
collagenase
90
more...
Compound
tyrosine
1075
oxygen
976
DNA
969
Dec
832
calcium
712
MEK
572
nitric oxide
559
threonine
431
serine
419
TNF
396
acetate
371
cAMP
309
glucose
270
NH2
229
MAP
218
ATP
193
sodium
187
cysteine
182
phosphate
182
hydrogen
178
more...