Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P51532 (transcriptional activator)
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Human Gene/Protein
hLBH 12.2
transcriptional activator 12.2
Nuclear autoantigen 12.2
ERG/EWS 12.2
CMPX1 12.2
epithelial discoidin domain receptor 1 12.2
TLX1 protein 12.2
Immediate early response 3 12.2
CCDC127 12.2
FUP1 11.7
TFECL 11.2
C11orf9 11.2
Myeloid Elf-1-like factor 11.2
GIG18 11.2
Eyes absent homolog 2 11.2
ZNFD 11.2
histidyl-tRNA synthetase-related 10.9
purine-rich element binding protein A 10.9
ZAN75 10.9
mitochondrial ribosomal protein S11 10.7
cell division protein kinase 6 10.7
Oct-1B 10.7
ZNF268 protein 10.7
SAF2 10.7
FKLF 10.4
SYT protein 10.4
TTMP 10.2
aristaless-like homeobox 4 10.2
ZNF397 10.2
AAD14 10.2
ZNF396 10.2
ZBTB48 10.2
EYA2 protein 10.2
zinc finger and SCAN domain containing 21 10.2
Zfp260 10.2
C1QTNF1 10.2
TXBP181 10.2
ZNF496 10.2
TIP120 9.9
MLL2 protein 9.9
SPATA12 9.9
ZNF410 9.9
Retinoid-related orphan receptor gamma 9.9
HKR3 9.9
zinc finger protein 2 9.9
LEUTX 9.9
DPRX 9.9
ZNF322 9.9
rab28 9.9
E2F2 protein 9.9
Collagenase 3 9.9
Arkadia-like 1 9.9
ZAP1 9.9
GCN1 9.8
EWS-Fli1 9.7
Cys-X-Cys) 9.7
TAFII80 9.7
HFH-3 9.7
DCLK3 9.7
DSCR6 9.7
Nuclear factor 1 9.7
MITF-C 9.7
KBTBD7 9.7
AUTS2 protein 9.7
Mvp1 9.7
Siah-interacting protein 9.7
CPA6 9.7
LBP-9 9.7
ZNF6 9.7
ZNF326 9.7
methyl-CpG binding domain protein 1 9.7
PC4 protein 9.7
TCDD-inducible poly(ADP-ribose) polymerase 9.7
Nuclear respiratory factor 1 9.6
HSF protein 9.5
ABCB4 protein 9.4
Myc-associated factor X 9.4
NOL7 9.4
Kruppel-like zinc finger protein 9.4
PPR1 9.4
more...
Disease
FBH3 10.2
PPR1 10.1
PAPB 9.9
CACD 9.4
CACD 9.2
Vaccinia virus infection 8.2
PGL2 8.0
Infective dermatitis 7.8
HFH 7.5
TSHoma 7.4
Central hypothyroidism 7.2
Greig cephalopolysyndactyly syndrome 7.1
CLN2 6.5
AUTS2 6.5
Teratocarcinoma 6.5
NPHP4 6.4
Lymphatic metastasis 6.3
FRAXE 6.3
CLN1 6.3
viral carcinogenesis 6.3
Sendai virus infection 6.3
Alveolar rhabdomyosarcoma 6.2
AHL 6.2
Subependymomas 6.2
MODY3 6.2
cancer angiogenesis 6.1
AN2 5.8
AD2 5.8
MODY1 5.8
Kaposi's Sarcoma 5.8
rhabdoid tumor of the kidney 5.7
Taybi 5.6
Benson 5.6
PKS 5.6
multicentric Castleman's disease 5.5
KCS 5.5
NPHS2 5.5
TSH deficiency 5.3
LIP 5.3
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy 5.2
Hepatocarcinogenesis 5.2
PHS 5.2
Carotid body tumors 5.2
crown gall 5.2
FUS 5.0
SGS 5.0
Carotid body 5.0
Visna 5.0
Carotid body 5.0
Carotid body 5.0
Tumor-induced osteomalacia 5.0
BOR syndrome 4.9
STY 4.9
PER 4.9
Legionella micdadei 4.9
Friend leukemia 4.9
LIN 4.8
XY females 4.8
HS3 4.8
HTLV-I 4.8
achromatopsia 4.8
Fuchs' endothelial dystrophy 4.8
dyserythropoietic anemia 4.8
OCM 4.7
adult T-cell leukemia/lymphoma 4.7
AML/MDS 4.7
adrenocortical cancer 4.7
DBA2 4.7
SGS 4.7
Growth failure 4.6
Drash syndrome 4.6
LWS 4.6
DRM 4.6
CLN3 4.6
PIT 4.6
FDH 4.5
Ewing's sarcoma 4.5
bacillary dysentery 4.5
Desmoplastic 4.5
embryonal carcinoma 4.4
more...
Symptom
benign congenital hypotonia 8.1
starvation 4.8
Noise-induced hearing loss 4.6
bladder pain 3.6
limb pain 2.9
CSR 2.8
hypotonia 1.3
twitching 1.3
skin irritation 1.2
hoarseness 0.7
HSA 0.7
diarrhea 0.6
memory loss 0.4
hepatosplenomegaly 0.1
acidity -0.1
hepatomegaly -0.3
collapse -0.6
arthralgia -0.6
ataxia -0.7
splenomegaly -1.0
agitation -1.3
weakness -1.4
stigma -1.5
functional recovery -1.5
exhaustion -1.5
analgesia -1.5
tremor -1.9
respiratory distress -2.0
seizures -2.0
angina -2.1
fatigue -2.4
abdominal pain -2.7
anesthesia -2.9
pain -3.4
Drug
1-Methylimidazole 9.1
Hypophosphite 8.7
AraC 8.5
Quinate 7.0
Tarivid 6.8
O-Acetylserine 6.8
AC2 6.6
GVG 6.5
DNase I 6.2
beta-Galactosidase 5.8
Pirarubicin 5.7
Azacytidine 5.7
ETS 5.3
DPE 5.2
FLM 5.0
Beta-2 4.9
Cellulase 4.8
Galactose 4.8
TAT 4.6
Olmesartan 4.5
PE2 4.4
Maltose 4.4
OMP 4.4
Gel 4.3
Clodronate 4.3
AIC 4.2
FLP 4.2
Doxycycline 4.2
Alanine 4.0
Heme 4.0
Copaxone 4.0
IFN-beta 3.9
Ganciclovir 3.7
TEL 3.6
AGG 3.6
Capsicum 3.4
FAD 3.4
ABC 3.4
PFT 3.3
Orphan 3.2
p75 3.1
Retinoic acid 3.1
CED 3.1
Meropenem 3.0
RFP 3.0
Meropenem 2.9
Kainic acid 2.9
uPA 2.8
lysine 2.8
Carotenoid 2.7
G418 2.7
L-tyrosine 2.6
Ranitidine 2.6
Rosiglitazone 2.6
Ofloxacin 2.6
Sodium nitroprusside 2.3
CTC 2.2
IFN-gamma 2.2
IL-11 2.1
MAP 2.1
Etoposide 2.1
Phentolamine 2.0
CoCl2 2.0
CoCl2 2.0
DPA 1.9
Arsenic trioxide 1.9
CTC 1.9
CCL 1.9
Glutathione 1.9
ETA 1.8
FeCl3 1.8
lactose 1.8
CTA 1.8
PCB 1.8
Glycyrrhiza 1.8
IPM 1.7
ROS 1.7
Growth hormone 1.7
Growth hormone 1.7
Leaf 1.7
more...
Enzyme
6-oxohexanoate dehydrogenase 12.2
precorrin isomerase 11.7
EC 1.2.2.3 11.2
3-phenylpropionate dioxygenase 9.9
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase 9.9
lactaldehyde reductase 9.7
4-hydroxybenzoate 3-monooxygenase 9.2
propanediol dehydrogenase 9.2
quinoline 2-oxidoreductase 8.8
aliphatic nitrilase 8.7
pterin-4alpha-carbinolamine dehydratase 8.7
tartrate dehydrogenase 8.3
wax synthase 8.2
phosphonoacetate hydrolase 8.0
2-oxopent-4-enoate hydratase 8.0
YgjG 7.9
acetone carboxylase 7.9
alpha-glucuronidase 7.9
nitric-oxide reductase 7.9
dinitrogenase reductase-activating glycohydrolase 7.9
PrpD 7.8
LasR 7.7
AAO3 7.5
p-hydroxybenzoate hydroxylase 7.4
benzoate-CoA ligase 7.3
methylmalonyl-CoA epimerase 7.2
aryl-alcohol dehydrogenase 7.2
myo-inositol-1-phosphate synthase 7.2
VanX 7.2
agmatine deiminase 7.2
phosphite dehydrogenase 7.2
methylisocitrate lyase 7.0
histidyl-tRNA synthetase 7.0
p-hydroxybenzoate hydroxylase 7.0
ATase 6.9
arabitol dehydrogenase 6.9
ent-kaurene oxidase 6.8
glucose-1-phosphate thymidylyltransferase 6.8
dienelactone hydrolase 6.8
FtsH protease 6.7
benzaldehyde dehydrogenase 6.6
benzaldehyde dehydrogenase 6.6
amylomaltase 6.6
methylglyoxal synthase 6.5
GMP synthase 6.5
acyl-ACP synthetase 6.4
nicotianamine synthase 6.4
pyrroline-5-carboxylate dehydrogenase 6.4
benzoate dioxygenase 6.4
PepX 6.3
acetylxylan esterase 6.3
collagenase 3 6.3
membrane-bound hydrogenase 6.3
urocanase 6.3
phosphoenolpyruvate synthase 6.2
lysine decarboxylase 6.2
histone acetyltransferase 6.2
galactokinase 6.1
SirA 6.1
benzylsuccinate synthase 6.1
homocitrate synthase 6.1
protocatechuate 3,4-dioxygenase 6.1
5beta-reductase 6.1
benzyl alcohol dehydrogenase 6.0
GMP synthetase 6.0
threonine synthase 6.0
3-hydroxy-3-methylglutaryl-CoA lyase 6.0
LexA repressor 6.0
phenol hydroxylase 5.9
formate dehydrogenase 5.9
chorismate synthase 5.9
muconate lactonizing enzyme 5.8
coproporphyrinogen oxidase 5.8
hormone-sensitive lipase 5.8
matrix metalloproteinase 14 5.8
6-phosphogluconolactonase 5.8
coproporphyrinogen III oxidase 5.8
histidinol dehydrogenase 5.8
cyclohexanone monooxygenase 5.7
aromatic amino acid aminotransferase 5.7
more...
Compound
OOHL 10.7
Aerotex 10.7
Daunomycinone 9.7
N-Acetylserine 9.4
Pyoluteorin 9.2
alpha-isopropylmalate 9.1
gamma-N-methylaminobutyrate 9.1
9(S)-HODE 9.1
Benzarone 8.8
2,3-DHP 8.2
Maltotriose 8.2
Pisatin 8.2
Pyrazofurin 7.9
A 174 7.9
PEK 7.7
PQM 7.7
Isomaltose 7.7
Ponasterone A 7.4
Thiostrepton 7.4
triphenylarsine 7.2
3,4-dimethylphenol 7.1
2-methylcitric acid 7.1
Oxypurinol 7.0
homoserine 6.8
homoserine 6.8
allantoate 6.8
3-chlorobenzoic acid 6.8
homoserine 6.8
ML-236B 6.6
1-methyl-1H-imidazole 6.6
Potassium permanganate 6.5
OLN 6.5
Octopine 6.5
TBP 6.5
N-acetylserine 6.5
1-dodecene 6.4
DT3 6.4
ATF 6.4
MHP 6.4
3-chlorobenzoic acid 6.3
Aloin 6.3
Cholesterol sulfate 6.3
TBP 6.3
Quinic acid 6.2
Pterin 6.2
K-40 6.2
Rifamycin 6.2
EPB 6.1
Benzbromarone 6.1
2-methyl-2-butene 6.1
HNS 6.1
Mimosine 5.9
Rifamycin 5.9
PTS 5.9
Rifamycin 5.8
Mimosine 5.8
KTS 5.8
Lanosterol 5.8
P 2 5.7
FOA 5.7
GA2 5.6
GAL 5.6
AIR 5.6
pyrroline-5-carboxylate 5.6
2-hexanol 5.6
TGT 5.5
mannitol-1-phosphate 5.5
coproporphyrinogen III 5.5
Ropinirole 5.5
2-oxoadipate 5.5
Virginiamycin 5.5
PRD 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
protoporphyrinogen IX 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
more...