Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P51532 (transcriptional activator)
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Human Gene/Protein
Nuclear autoantigen 12.2
Immediate early response 3 12.2
ERG/EWS 12.2
TLX1 protein 12.2
hLBH 12.2
CCDC127 12.2
transcriptional activator 12.2
epithelial discoidin domain receptor 1 12.2
CMPX1 12.2
FUP1 11.7
GIG18 11.2
ZNFD 11.2
C11orf9 11.2
Myeloid Elf-1-like factor 11.2
Eyes absent homolog 2 11.2
TFECL 11.2
histidyl-tRNA synthetase-related 10.9
purine-rich element binding protein A 10.9
ZAN75 10.9
ZNF268 protein 10.7
cell division protein kinase 6 10.7
Oct-1B 10.7
SAF2 10.7
mitochondrial ribosomal protein S11 10.7
SYT protein 10.4
FKLF 10.4
ZNF396 10.2
EYA2 protein 10.2
C1QTNF1 10.2
ZNF496 10.2
AAD14 10.2
zinc finger and SCAN domain containing 21 10.2
aristaless-like homeobox 4 10.2
Zfp260 10.2
TTMP 10.2
ZBTB48 10.2
ZNF397 10.2
TXBP181 10.2
rab28 9.9
DPRX 9.9
Retinoid-related orphan receptor gamma 9.9
LEUTX 9.9
Arkadia-like 1 9.9
Collagenase 3 9.9
MLL2 protein 9.9
HKR3 9.9
SPATA12 9.9
TIP120 9.9
zinc finger protein 2 9.9
E2F2 protein 9.9
ZNF322 9.9
ZNF410 9.9
ZAP1 9.9
GCN1 9.8
EWS-Fli1 9.7
Cys-X-Cys) 9.7
DSCR6 9.7
Mvp1 9.7
Siah-interacting protein 9.7
TAFII80 9.7
AUTS2 protein 9.7
ZNF6 9.7
PC4 protein 9.7
TCDD-inducible poly(ADP-ribose) polymerase 9.7
Nuclear factor 1 9.7
DCLK3 9.7
LBP-9 9.7
CPA6 9.7
MITF-C 9.7
HFH-3 9.7
ZNF326 9.7
methyl-CpG binding domain protein 1 9.7
KBTBD7 9.7
Nuclear respiratory factor 1 9.6
HSF protein 9.5
ABCB4 protein 9.4
Myc-associated factor X 9.4
mitogaligin 9.4
lipid phosphate phosphatase-related protein type 4 9.4
ERR3 9.4
NOL7 9.4
CUX1 protein 9.4
ISYNA1 9.4
Kruppel-like zinc finger protein 9.4
PPR1 9.4
Importin 13 9.4
SRB7 9.4
IGL@ 9.4
Intestinal mucin 9.4
CACD 9.4
histidyl tRNA synthetase 9.3
A-myb 9.3
transcription factor Pax-5 9.2
SES1 9.2
UPP1 9.2
PUT1 9.2
NOT3 9.2
PRBP 9.2
POU5F1P1 9.2
IES2 9.2
NRF1 protein 9.2
FOX3 9.2
ZF7 9.2
ubiquinone-binding protein 9.2
WNT1 inducible signaling pathway protein 2 9.2
pre-B-cell leukemia transcription factor 1 9.2
transcription factor EC 9.2
SARP 9.1
CycT2 9.1
OAF1 9.1
HSF2 protein 9.1
aml1 9.1
X11L2 9.1
LBP-1a 9.1
estrogen receptor variant 9.1
DMTF1 9.1
PSP2 9.1
FOXJ2 9.0
NPH4 9.0
TG protein 9.0
PFDN2 8.9
ZNF711 8.9
ZF6 8.9
IGK@ 8.9
GLI2 protein 8.9
RRE1 8.9
TIEG2 8.9
DABP 8.9
MED6 8.9
MAZR 8.9
coxsackie virus and adenovirus receptor 8.9
NCYM 8.8
GAL4 8.8
zinc finger protein 423 8.8
TREF 8.8
ARID4B 8.8
SAP-1a 8.8
RNA editase 8.8
TBP-interacting protein 8.8
CDC-like kinase 2 8.8
Interferon regulatory factor 1 8.8
HERP1 8.7
PCGF3 8.7
32 AA 8.7
B99 8.7
HBP2 8.7
SPI-B 8.7
AP2B1 8.7
Sgn1 8.7
NR3B3 8.7
Fez family zinc finger protein 1 8.7
MI-ER1 8.7
p53DINP1 8.7
msg1 8.7
SPX2 8.7
hDMP1 8.7
NRF3 8.7
YAP2 8.6
GORAB 8.6
TAF4 8.6
more...
Disease
FBH3 10.2
PPR1 10.1
PAPB 9.9
CACD 9.4
CACD 9.2
Vaccinia virus infection 8.2
PGL2 8.0
Infective dermatitis 7.8
HFH 7.5
TSHoma 7.4
Central hypothyroidism 7.2
Greig cephalopolysyndactyly syndrome 7.1
CLN2 6.5
AUTS2 6.5
Teratocarcinoma 6.5
NPHP4 6.4
Lymphatic metastasis 6.3
FRAXE 6.3
CLN1 6.3
viral carcinogenesis 6.3
Sendai virus infection 6.3
AHL 6.2
Alveolar rhabdomyosarcoma 6.2
Subependymomas 6.2
MODY3 6.2
cancer angiogenesis 6.1
AN2 5.8
AD2 5.8
MODY1 5.8
Kaposi's Sarcoma 5.8
rhabdoid tumor of the kidney 5.7
Taybi 5.6
Benson 5.6
PKS 5.6
multicentric Castleman's disease 5.5
KCS 5.5
NPHS2 5.5
TSH deficiency 5.3
LIP 5.3
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy 5.2
Hepatocarcinogenesis 5.2
PHS 5.2
Carotid body tumors 5.2
crown gall 5.2
FUS 5.0
SGS 5.0
Carotid body 5.0
Tumor-induced osteomalacia 5.0
Visna 5.0
Carotid body 5.0
Carotid body 5.0
BOR syndrome 4.9
STY 4.9
PER 4.9
Legionella micdadei 4.9
Friend leukemia 4.9
LIN 4.8
XY females 4.8
HS3 4.8
HTLV-I 4.8
achromatopsia 4.8
Fuchs' endothelial dystrophy 4.8
dyserythropoietic anemia 4.8
OCM 4.7
adult T-cell leukemia/lymphoma 4.7
AML/MDS 4.7
adrenocortical cancer 4.7
DBA2 4.7
SGS 4.7
Growth failure 4.6
LWS 4.6
Drash syndrome 4.6
CLN3 4.6
DRM 4.6
PIT 4.6
FDH 4.5
Ewing's sarcoma 4.5
bacillary dysentery 4.5
Desmoplastic 4.5
embryonal carcinoma 4.4
CP1 4.4
Kaposi's sarcoma 4.4
IS2 4.4
AD1 4.4
HMR 4.3
familial Alzheimer disease 4.3
monocytic leukemia 4.3
HP2 4.3
HML 4.3
GRTH 4.3
leukemogenesis 4.3
IS3 4.2
ear infection 4.2
Epstein 4.2
velocardiofacial syndrome 4.2
canker 4.2
OAR 4.2
NLS 4.2
BLS 4.2
Rust 4.2
Shigella flexneri 4.2
PIE 4.1
ACS1 4.1
hereditary persistence of fetal hemoglobin 4.1
Yersinia 4.1
Human immunodeficiency virus type 4.1
DNT 4.0
hormone deficiency 4.0
hyperosmolality 4.0
LAP 4.0
orf 4.0
AAA 4.0
NPHP1 4.0
WT1 4.0
blood cancer 4.0
pseudotuberculosis 4.0
thyroid neoplasm 3.9
eustachian tube dysfunction 3.9
Brock 3.9
CYLD 3.9
CAA 3.9
reticuloendotheliosis 3.9
DMS 3.9
Sotos syndrome 3.9
renal tubular acidosis 3.9
SBS 3.8
SBS 3.8
herpes simplex 3.8
EKC 3.8
cholera 3.8
AIC 3.8
INS 3.8
RP4 3.8
HTL 3.7
erythroblastosis 3.7
MBS 3.7
Klippel-Trenaunay syndrome 3.7
chronic phase CML 3.7
Sutton 3.7
EBV infection 3.7
Crabs 3.7
retinoblastoma 3.7
PDR 3.7
Recruitment 3.6
EL4 3.6
FTLD 3.6
plant disease 3.6
bovine leukemia 3.6
Renal fibrosis 3.6
erythrocytosis 3.6
MODY 3.6
dermatofibroma 3.5
MSA 3.5
avian sarcoma 3.5
RP11 3.5
primitive neuroectodermal tumor 3.5
RBS 3.5
Rous sarcoma 3.5
CAA 3.5
NS2 3.5
more...
Symptom
benign congenital hypotonia 8.1
starvation 4.8
Noise-induced hearing loss 4.6
bladder pain 3.6
limb pain 2.9
CSR 2.8
hypotonia 1.3
twitching 1.3
skin irritation 1.2
hoarseness 0.7
HSA 0.7
diarrhea 0.6
memory loss 0.4
hepatosplenomegaly 0.1
acidity -0.1
hepatomegaly -0.3
collapse -0.6
arthralgia -0.6
ataxia -0.7
splenomegaly -1.0
agitation -1.3
weakness -1.4
stigma -1.5
functional recovery -1.5
exhaustion -1.5
analgesia -1.5
tremor -1.9
respiratory distress -2.0
seizures -2.0
angina -2.1
fatigue -2.4
abdominal pain -2.7
anesthesia -2.9
pain -3.4
Drug
1-Methylimidazole 9.1
Hypophosphite 8.7
AraC 8.5
Quinate 7.0
O-Acetylserine 6.8
Tarivid 6.8
AC2 6.6
GVG 6.5
DNase I 6.2
beta-Galactosidase 5.8
Pirarubicin 5.7
Azacytidine 5.7
ETS 5.3
DPE 5.2
FLM 5.0
Beta-2 4.9
Cellulase 4.8
Galactose 4.8
TAT 4.6
Olmesartan 4.5
PE2 4.4
Maltose 4.4
OMP 4.4
Gel 4.3
Clodronate 4.3
AIC 4.2
FLP 4.2
Doxycycline 4.2
Alanine 4.0
Heme 4.0
Copaxone 4.0
IFN-beta 3.9
Ganciclovir 3.7
TEL 3.6
AGG 3.6
Capsicum 3.4
FAD 3.4
ABC 3.4
PFT 3.3
Orphan 3.2
p75 3.1
Retinoic acid 3.1
CED 3.1
Meropenem 3.0
RFP 3.0
Meropenem 2.9
Kainic acid 2.9
uPA 2.8
lysine 2.8
Carotenoid 2.7
G418 2.7
L-tyrosine 2.6
Ranitidine 2.6
Rosiglitazone 2.6
Ofloxacin 2.6
Sodium nitroprusside 2.3
CTC 2.2
IFN-gamma 2.2
IL-11 2.1
MAP 2.1
Etoposide 2.1
Phentolamine 2.0
CoCl2 2.0
CoCl2 2.0
DPA 1.9
Arsenic trioxide 1.9
CTC 1.9
CCL 1.9
Glutathione 1.9
ETA 1.8
FeCl3 1.8
lactose 1.8
CTA 1.8
PCB 1.8
Glycyrrhiza 1.8
IPM 1.7
ROS 1.7
Growth hormone 1.7
Growth hormone 1.7
Leaf 1.7
IL-2 1.6
Ethanol 1.6
Biopolymers 1.5
NH3 1.5
Parkin 1.4
TTC 1.4
Parkin 1.4
Asn 1.3
Itraconazole 1.3
ADR 1.2
EPI 1.2
NAG 1.2
ACT 1.2
NADH 1.2
nitroglycerin 1.1
Glycerol 1.1
Adriamycin 1.1
ampicillin 1.0
pyridoxal phosphate 0.9
Forskolin 0.9
Alliance 0.9
Fluorescein 0.8
ALA 0.8
CTX 0.8
CTX 0.8
CAM 0.7
ADM 0.6
CTX 0.5
MRC 0.5
Kenyan 0.5
Glucagon 0.4
Fluorescein 0.4
niacin 0.4
EE2 0.3
Portal 0.2
CSF 0.1
caffeine -0.2
ascorbate -0.2
Nephron -0.3
Mutagen -0.3
Indomethacin -0.4
CaCl2 -0.4
CaCl2 -0.4
CaCl2 -0.4
citric acid -1.0
Dermatol -2.4
Dial -2.7
Monit -2.9
Cardiovasc -4.4
Enzyme
6-oxohexanoate dehydrogenase 12.2
precorrin isomerase 11.7
EC 1.2.2.3 11.2
3-phenylpropionate dioxygenase 9.9
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase 9.9
lactaldehyde reductase 9.7
4-hydroxybenzoate 3-monooxygenase 9.2
propanediol dehydrogenase 9.2
quinoline 2-oxidoreductase 8.8
aliphatic nitrilase 8.7
pterin-4alpha-carbinolamine dehydratase 8.7
tartrate dehydrogenase 8.3
wax synthase 8.2
2-oxopent-4-enoate hydratase 8.0
phosphonoacetate hydrolase 8.0
acetone carboxylase 7.9
YgjG 7.9
nitric-oxide reductase 7.9
alpha-glucuronidase 7.9
dinitrogenase reductase-activating glycohydrolase 7.9
PrpD 7.8
LasR 7.7
AAO3 7.5
p-hydroxybenzoate hydroxylase 7.4
benzoate-CoA ligase 7.3
methylmalonyl-CoA epimerase 7.2
aryl-alcohol dehydrogenase 7.2
myo-inositol-1-phosphate synthase 7.2
VanX 7.2
agmatine deiminase 7.2
phosphite dehydrogenase 7.2
methylisocitrate lyase 7.0
histidyl-tRNA synthetase 7.0
p-hydroxybenzoate hydroxylase 7.0
ATase 6.9
arabitol dehydrogenase 6.9
ent-kaurene oxidase 6.8
glucose-1-phosphate thymidylyltransferase 6.8
dienelactone hydrolase 6.8
FtsH protease 6.7
benzaldehyde dehydrogenase 6.6
benzaldehyde dehydrogenase 6.6
amylomaltase 6.6
methylglyoxal synthase 6.5
GMP synthase 6.5
acyl-ACP synthetase 6.4
nicotianamine synthase 6.4
pyrroline-5-carboxylate dehydrogenase 6.4
benzoate dioxygenase 6.4
PepX 6.3
acetylxylan esterase 6.3
collagenase 3 6.3
membrane-bound hydrogenase 6.3
urocanase 6.3
phosphoenolpyruvate synthase 6.2
lysine decarboxylase 6.2
histone acetyltransferase 6.2
galactokinase 6.1
SirA 6.1
benzylsuccinate synthase 6.1
homocitrate synthase 6.1
protocatechuate 3,4-dioxygenase 6.1
5beta-reductase 6.1
benzyl alcohol dehydrogenase 6.0
GMP synthetase 6.0
threonine synthase 6.0
3-hydroxy-3-methylglutaryl-CoA lyase 6.0
LexA repressor 6.0
phenol hydroxylase 5.9
formate dehydrogenase 5.9
chorismate synthase 5.9
muconate lactonizing enzyme 5.8
coproporphyrinogen oxidase 5.8
hormone-sensitive lipase 5.8
6-phosphogluconolactonase 5.8
matrix metalloproteinase 14 5.8
coproporphyrinogen III oxidase 5.8
histidinol dehydrogenase 5.8
cyclohexanone monooxygenase 5.7
aromatic amino acid aminotransferase 5.7
isovaleryl-CoA dehydrogenase 5.7
PHD 5.7
histidine kinase 5.7
branched-chain alpha-keto acid dehydrogenase 5.6
transaldolase 5.6
cystathionine beta-lyase 5.6
phosphatidylglycerophosphate synthase 5.6
quinolinic acid phosphoribosyltransferase 5.6
alpha-isopropylmalate synthase 5.6
proline dehydrogenase 5.6
ferric chelate reductase 5.5
glucose permease 5.5
isoprene synthase 5.5
RNA polymerase 5.5
feruloyl esterase 5.5
formate dehydrogenase 5.5
formate dehydrogenase 5.5
sulfite reductase 5.5
sulfite reductase 5.5
nitrogenase 5.5
chloramphenicol acetyltransferase 5.5
dihydrodiol dehydrogenase 5.5
CTS2 5.4
sulfite reductase 5.4
Pla 5.4
NCED 5.4
saccharopine dehydrogenase 5.4
sterol carrier protein 5.4
3-dehydroquinate 5.4
Lys4 5.4
carbamate kinase 5.4
HMG-CoA synthase 5.3
xyloglucan endotransglycosylase 5.3
amidophosphoribosyltransferase 5.3
fatty acid elongase 5.2
proline iminopeptidase 5.2
TGT 5.2
HOA 5.2
oligopeptide permease 5.2
malate synthase 5.2
phytoene synthase 5.2
chitin deacetylase 5.2
ubiquitin-protein ligase 5.2
proline oxidase 5.2
GAS 5.2
biliverdin reductase 5.1
isochorismate synthase 5.1
diol dehydratase 5.1
CTD kinase 5.1
isocitrate lyase 5.1
arginine deiminase 5.1
endonuclease V 5.1
flavonol synthase 5.1
STK 5.0
SLB 5.0
flavin reductase 5.0
murein hydrolase 5.0
ClpP 5.0
calpain 3 5.0
nitrite reductase 4.9
mannitol dehydrogenase 4.9
S1 nuclease 4.9
hydrogenase 4.9
type 1 protein phosphatase 4.9
hydrogenase 4.9
nitrite reductase 4.9
nitrite reductase 4.8
PBP5 4.8
xylulokinase 4.8
cystathionine gamma-lyase 4.8
anthranilate synthase 4.8
cystathionine gamma-synthase 4.8
lysine acetyltransferase 4.8
polynucleotide phosphorylase 4.8
TOR 4.7
CLK1 4.7
mannitol dehydrogenase 4.7
catechol 2,3-dioxygenase 4.7
betaine aldehyde dehydrogenase 4.6
TAT 4.6
more...
Compound
OOHL 10.7
Aerotex 10.7
Daunomycinone 9.7
N-Acetylserine 9.4
Pyoluteorin 9.2
alpha-isopropylmalate 9.1
9(S)-HODE 9.1
gamma-N-methylaminobutyrate 9.1
Benzarone 8.8
2,3-DHP 8.2
Maltotriose 8.2
Pisatin 8.2
Pyrazofurin 7.9
A 174 7.9
PEK 7.7
Isomaltose 7.7
PQM 7.7
Ponasterone A 7.4
Thiostrepton 7.4
triphenylarsine 7.2
2-methylcitric acid 7.1
3,4-dimethylphenol 7.1
Oxypurinol 7.0
homoserine 6.8
homoserine 6.8
allantoate 6.8
3-chlorobenzoic acid 6.8
homoserine 6.8
ML-236B 6.6
1-methyl-1H-imidazole 6.6
OLN 6.5
Potassium permanganate 6.5
Octopine 6.5
TBP 6.5
N-acetylserine 6.5
DT3 6.4
1-dodecene 6.4
ATF 6.4
MHP 6.4
3-chlorobenzoic acid 6.3
Aloin 6.3
Cholesterol sulfate 6.3
TBP 6.3
Quinic acid 6.2
Pterin 6.2
K-40 6.2
Rifamycin 6.2
EPB 6.1
Benzbromarone 6.1
2-methyl-2-butene 6.1
HNS 6.1
Mimosine 5.9
Rifamycin 5.9
PTS 5.9
Mimosine 5.8
Rifamycin 5.8
KTS 5.8
Lanosterol 5.8
P 2 5.7
FOA 5.7
GA2 5.6
GAL 5.6
AIR 5.6
pyrroline-5-carboxylate 5.6
2-hexanol 5.6
TGT 5.5
mannitol-1-phosphate 5.5
coproporphyrinogen III 5.5
2-oxoadipate 5.5
Ropinirole 5.5
Virginiamycin 5.5
PRD 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
protoporphyrinogen IX 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.4
2-hydroxybenzaldehyde 5.3
1-indanone 5.3
1-indanone 5.3
Exotoxin 5.3
Ecdysone 5.2
(-)-quinic acid 5.2
Paromomycin 5.2
Taxifolin 5.2
Formononetin 5.2
Rifamycin 5.2
2-hydroxybenzaldehyde 5.2
AF-2 5.1
TTA 5.1
O-acetylserine 5.1
MnO4 5.1
protocatechuate 5.1
GA3 5.1
GDP-D-mannose 5.1
MBH 5.1
2-hydroxybenzaldehyde 5.0
MAL 5.0
benzenesulfonyl fluoride 5.0
decarboxylated S-adenosylmethionine 5.0
ESE 4.9
Pullulan 4.9
O-acetylserine 4.9
TAR 4.9
Celastrol 4.9
4-OHT 4.8
Dihydroxyacetone 4.8
CUE 4.8
Galactose 4.8
Anthocyanin 4.8
2-hydroxybenzaldehyde 4.8
MNT 4.7
Methoprene 4.7
DSE 4.7
PHB 4.7
Biliverdin 4.7
triphenylphosphine oxide 4.6
DMS 4.6
8-hydroxyguanosine 4.6
Ethylene 4.6
Formate 4.6
ABA 4.6
Tetramethylpyrazine 4.5
GC-1 4.5
ABA 4.5
Tauroursodeoxycholic acid 4.5
Fumarate 4.5
O-acetylserine 4.5
TET 4.5
TET 4.5
meso-diaminopimelate 4.5
Panam 4.5
N-acetylcysteine 4.5
C2H2 4.4
fructose-6-P 4.4
2-hydroxybenzaldehyde 4.4
TIF 4.4
1-dodecanol 4.4
4-ethylphenol 4.4
Tetracycline 4.4
Maltose 4.4
Levan 4.3
ASK 4.3
3-hydroxy-2-butanone 4.3
GA1 4.3
OMP 4.3
Fisetin 4.3
4-hydroxyphenylpyruvate 4.3
more...