Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P51532 (transcriptional activator)
 6,546 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
transcriptional activator 6546
Mol 1144
Sep 453
DNA-binding domain 277
transcriptional repressor 272
fused 267
GAL4 246
p53 232
Pseudomonas 191
transcriptional regulator 173
histone 165
leucine zipper 136
RNA polymerase II 132
DNase I 127
ATP 125
zinc finger 117
polypeptide 102
Sp1 100
DNA-binding protein 92
cytokine 90
Gen 84
beta-catenin 80
p300 79
ubiquitin 75
interferon 74
proteasome 74
nuclear protein 71
AP-1 69
SWI 69
AMP 68
CREB 68
insulin 67
erythroid 66
transactivator 66
ATPase 65
MYB 60
p65 57
endoplasmic reticulum 56
basic helix-loop-helix 56
lymphoid 56
phosphatase 55
CBP 51
NMR 51
p21 51
reductase 50
unknown function 49
EBP 49
TFIID 48
histone H3 45
cyclin 45
histone deacetylase 45
NAC 44
GAL 44
catenin 44
threonine 43
nuclear receptor 43
TFIIB 43
c-Jun 42
MAPK 42
membrane protein 42
p50 40
tRNA 40
proto-oncogene 40
c-myc 39
SOD 38
transcriptional coactivator 37
estrogen receptor 37
homeobox 37
lipopolysaccharide 36
CBF1 36
AP2 35
chimeric protein 35
vascular endothelial growth factor 35
histone acetyltransferase 35
TATA-binding protein 34
IFN 34
E-cadherin 34
transcriptional factor 34
HIF-1alpha 34
IRF-1 33
ATF 33
zinc finger protein 33
membrane-bound 32
GAL1 32
tumor necrosis factor 32
dimeric 32
A. nidulans 31
c-Myc 30
p38 29
GST 29
catalase 29
IRF-2 29
CAT 28
gut 28
CD4 28
IFN-gamma 27
EWS 26
GCN2 26
c-fos 26
ORF 26
DNA binding protein 25
CREB-binding protein 25
ERF 25
cyclin D1 25
TBP 25
ACS 25
hormone-sensitive lipase 25
caspase-3 25
general transcription factor 24
methyltransferase 24
cyclin-dependent kinase 24
CRP 24
ras 24
tumour suppressor 24
HIF-1 24
beta-glucuronidase 24
TCF 24
thymidine kinase 23
Nrf2 23
MyoD 23
ADP 23
WT1 23
acetyltransferase 22
Pol 22
erythropoietin 22
ubiquitin ligase 22
CBF 22
Bot 22
glucocorticoid receptor 21
serum response factor 21
interacting protein 21
thymus 21
ADH2 21
repressor protein 20
thyroid hormone 20
metallothionein 20
GTP 19
AP1 19
c-myb 19
interferon regulatory factor-1 19
MDM2 19
ABC 19
tyrosine kinase 19
cryptic 19
glutathione S-transferase 19
cAMP-response element 19
STAT3 19
c-Rel 19
hedgehog 19
CLOCK 18
p53 target 18
SCF 18
HDAC1 18
porin 18
STAT 18
phosphoprotein 18
tumor necrosis factor alpha 18
RNA-binding protein 17
MHC class I 17
MAP kinase 17
more...
Disease
cancer 402
tumor 335
leukemia 127
tumorigenesis 117
HIV 105
Epstein 92
breast cancer 87
herpes simplex 82
immunodeficiency 71
cold 70
cholera 59
carcinoma 52
Klebsiella 50
hepatocellular carcinoma 43
tumor progression 42
tumor growth 40
dehydration 39
Kaposi's sarcoma 38
virus infection 37
carcinogenesis 35
Yersinia 34
hepatitis B 33
diabetes 32
lymphoma 30
Mycobacterium 30
prostate cancer 29
retinoblastoma 29
colorectal cancer 29
melanoma 29
colon cancer 27
WT1 27
infectious diseases 26
cytomegalovirus 25
Ewing's sarcoma 23
AIDS 22
Infection 22
ischemia 22
tuberculosis 22
acute myeloid leukemia 21
obesity 19
neuroblastoma 18
MCF 18
SDS 17
anemia 16
leukemogenesis 16
depression 16
pheochromocytoma 15
lung cancer 15
glioma 15
embryonal carcinoma 15
sarcoma 14
adult T-cell leukemia/lymphoma 14
Shigella 14
HTLV-I 14
pertussis 13
APC 13
metastases 13
type 2 diabetes 13
Alzheimer's disease 13
stroke 13
B-cell lymphoma 12
mammary tumor 12
varicella 12
PCC 12
multiple myeloma 12
atherosclerosis 12
abdominal aortic aneurysm 11
Bordetella 11
adenocarcinoma 11
GSH 11
Shigella flexneri 11
squamous cell carcinoma 11
EBV infection 11
rhabdomyosarcoma 10
cervical cancer 10
AAA 10
Proteus 10
Burkitt's lymphoma 10
fibrosarcoma 10
PPR1 10
osteosarcoma 9
gastric cancer 9
acute lymphoblastic leukemia 9
heart failure 9
ovarian cancer 9
hypertension 9
myocardial infarction 8
Huntington's disease 8
pseudotuberculosis 8
Benson 8
Blocking 8
tumor angiogenesis 8
malaria 8
FUS 8
Leukemia 8
Hippel 8
epilepsy 8
lung carcinoma 8
Recruitment 8
myocardial ischemia 8
familial adenomatous polyposis 8
erythroleukemia 8
latent infection 7
Rous sarcoma 7
myelodysplastic syndrome 7
Rett syndrome 7
acute promyelocytic leukemia 7
PKS 7
rheumatoid arthritis 7
mental retardation 7
CLN2 7
glioblastoma 7
fatty liver 7
bends 7
mental retardation 7
insulinoma 7
basal cell carcinoma 7
liver cancer 7
ATM 7
cystic fibrosis 7
hepatitis C 7
PER 7
dysplasia 7
renal cancer 6
autism 6
worms 6
candidiasis 6
pancreatic cancer 6
TCP 6
bacterial infection 6
Shiga 6
herpes 6
osteoarthritis 6
sepsis 6
vaccinia 6
systemic lupus erythematosus 6
cerebral ischemia 6
asthma 6
pneumonia 6
HAM 6
renal tubular acidosis 6
Hodgkin's disease 5
infertility 5
Haemophilus 5
coronary artery disease 5
muscular atrophy 5
canker 5
liver cancer 5
Legionella 5
sepsis 5
parvovirus 5
SCID 5
neoplastic transformation 5
uterus 5
multicentric Castleman's disease 5
CAP 5
epithelial ovarian cancer 5
Human immunodeficiency virus type 5
renal cell carcinoma 5
thalassemia 5
more...
Symptom
starvation 140
diarrhea 18
pain 5
collapse 4
seizures 4
acidity 3
weakness 3
anesthesia 3
hypotonia 3
ataxia 2
analgesia 2
fatigue 2
twitching 1
Noise-induced hearing loss 1
splenomegaly 1
skin irritation 1
bladder pain 1
arthralgia 1
agitation 1
exhaustion 1
CSR 1
angina 1
respiratory distress 1
hepatomegaly 1
limb pain 1
functional recovery 1
hepatosplenomegaly 1
benign congenital hypotonia 1
tremor 1
memory loss 1
HSA 1
abdominal pain 1
hoarseness 1
stigma 1
Drug
DNase I 128
lysine 82
AraC 77
Gel 59
IFN-gamma 27
ETS 21
ABC 19
IL-2 18
MAP 14
Leaf 14
ROS 13
lactose 12
FAD 12
TAT 12
Dermatol 10
NADH 10
Heme 10
IFN-beta 9
Alanine 9
CSF 7
ampicillin 7
AC2 7
p75 7
Galactose 6
Asn 6
Ethanol 6
Retinoic acid 6
Biopolymers 5
Capsicum 5
beta-Galactosidase 5
Glutathione 4
NH3 4
FLP 4
ascorbate 4
Doxycycline 4
caffeine 4
nitroglycerin 4
CTX 3
L-tyrosine 3
GVG 3
Nephron 3
PCB 3
Cellulase 3
uPA 3
G418 3
Growth hormone 2
TEL 2
OMP 2
ETA 2
Cardiovasc 2
EE2 2
AGG 2
CAM 2
CTX 2
AIC 2
RFP 2
Ranitidine 2
CTX 2
Growth hormone 2
Maltose 2
Adriamycin 2
Ganciclovir 2
MRC 1
CTA 1
Tarivid 1
pyridoxal phosphate 1
citric acid 1
Dial 1
CTC 1
DPA 1
Parkin 1
Indomethacin 1
FeCl3 1
Sodium nitroprusside 1
Phentolamine 1
Hypophosphite 1
Clodronate 1
Carotenoid 1
Fluorescein 1
EPI 1
IPM 1
TTC 1
Monit 1
Portal 1
Etoposide 1
CCL 1
Beta-2 1
Meropenem 1
Meropenem 1
ADR 1
Parkin 1
Kenyan 1
DPE 1
Orphan 1
Olmesartan 1
O-Acetylserine 1
Ofloxacin 1
IL-11 1
CED 1
CaCl2 1
Rosiglitazone 1
FLM 1
CaCl2 1
Mutagen 1
Pirarubicin 1
Glycerol 1
CTC 1
Arsenic trioxide 1
NAG 1
ACT 1
Itraconazole 1
ALA 1
Fluorescein 1
Glycyrrhiza 1
Quinate 1
ADM 1
PE2 1
Glucagon 1
Kainic acid 1
Azacytidine 1
CoCl2 1
PFT 1
Copaxone 1
1-Methylimidazole 1
Forskolin 1
CaCl2 1
niacin 1
Alliance 1
CoCl2 1
Enzyme
RNA polymerase 326
protein kinase 184
luciferase 160
mitogen-activated protein kinase 102
proteasome 79
beta-galactosidase 71
ATPase 67
ERK 64
catalase 59
glutathione S-transferase 49
chloramphenicol acetyltransferase 46
histone acetyltransferase 40
LasR 38
nitrogenase 33
protein kinase C 29
calcineurin 28
histidine kinase 25
focal adhesion kinase 25
ACS 25
hormone-sensitive lipase 25
beta-glucuronidase 24
S1 nuclease 23
thymidine kinase 23
reverse transcriptase 22
hydrogenase 21
cellulase 21
hydrogenase 21
superoxide dismutase 20
cdc2 19
MEK 19
aldehyde dehydrogenase 18
caspase-3 18
alcohol dehydrogenase 18
AMPK 17
elastase 16
nitrate reductase 16
DNA polymerase 16
nitrate reductase 16
APC 15
GSK 14
nitrate reductase 14
nitrate reductase 14
nitrate reductase 14
nitrate reductase 14
endonuclease 13
trypsin 13
RNase 13
RNase 13
alkaline phosphatase 13
AMP-activated protein kinase 13
formate dehydrogenase 13
alpha-amylase 12
xylanase 12
nitrite reductase 12
phospholipase C 12
TAT 12
aldehyde dehydrogenase 12
xylanase 12
PARP 11
aldehyde dehydrogenase 11
nitrite reductase 11
aldehyde dehydrogenase 11
phosphodiesterase 11
nitrite reductase 11
aldehyde dehydrogenase 11
DNase 11
MAP 11
peroxidase 10
DNA methyltransferase 10
collagenase 10
transcriptase 10
formate dehydrogenase 9
urease 9
beta-lactamase 9
PHD 9
galactokinase 9
urease 9
formate dehydrogenase 9
ornithine decarboxylase 8
TOR 8
Pla 8
MMP 8
glucoamylase 8
adenylate cyclase 8
phosphatidylinositol 3-kinase 8
pyruvate kinase 8
cytochrome oxidase 8
phosphoenolpyruvate carboxykinase 7
glucose-6-phosphate dehydrogenase 7
phosphoenolpyruvate carboxykinase 7
acid phosphatase 7
isocitrate lyase 7
prolyl hydroxylase 7
demethylase 7
phosphoenolpyruvate carboxykinase 7
GAS 7
lysine decarboxylase 6
IKK 6
arginine deiminase 6
MAT 6
ubiquitin-protein ligase 6
caspase-1 6
p-hydroxybenzoate hydroxylase 6
prostate-specific antigen 6
phosphoglycerate kinase 6
pyruvate dehydrogenase 6
urokinase-type plasminogen activator 6
invertase 6
glyceraldehyde-3-phosphate dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
deaminase 6
N-acetyltransferase 6
glutathione reductase 5
cellobiohydrolase 5
complex I 5
glucose-6-phosphatase 5
glyceraldehyde-3-phosphate dehydrogenase 5
micrococcal nuclease 5
glutamine synthetase 5
gamma-glutamyl transpeptidase 5
lipase 5
ribonuclease 5
alpha-glucosidase 5
lysozyme 5
chitinase 5
ClpP 5
ALA synthase 5
firefly luciferase 5
ribonuclease 5
MAT 5
AMPK 5
aldose reductase 5
transketolase 5
glyceraldehyde-3-phosphate dehydrogenase 5
histidyl-tRNA synthetase 5
glyceraldehyde-3-phosphate dehydrogenase 5
cellulose synthase 4
CaMKII 4
thioredoxin reductase 4
thrombin 4
polynucleotide phosphorylase 4
TGT 4
pyruvate decarboxylase 4
sulfatase 4
glutamate dehydrogenase 4
DNA ligase 4
acetyl-CoA carboxylase 4
glycerol-3-phosphate dehydrogenase 4
PAL 4
chaperonin 4
DNA ligase 4
myo-inositol-1-phosphate synthase 4
amylomaltase 4
heme oxygenase 4
CD10 4
MMP-3 4
kinesin 4
acyl-CoA synthetase 4
rubisco 4
protein phosphatase 2A 4
more...
Compound
DNA 2019
Dec 518
oxygen 255
glucose 217
nitrogen 190
zinc 181
phosphate 139
ATP 125
iron 116
serine 107
cysteine 106
leucine 103
His 100
lysine 99
cAMP 95
alanine 83
galactose 76
proline 74
homoserine 71
homoserine 71
homoserine 71
AMP 68
salt 67
calcium 65
tyrosine 64
hydrogen 63
arginine 61
retinoic acid 61
acetate 60
water 59
threonine 56
tryptophan 55
ammonium 51
copper 49
N-acetylcysteine 49
methionine 48
glutamine 48
GAL 47
ethanol 46
Panam 44
NH2 40
sodium 40
Clin 36
ATF 33
sulfate 33
glutamate 32
nitrate 32
xylose 31
tryptophan 30
glycerol 30
salicylic acid 30
Phe 29
tryptophan 29
tryptophan 29
CAT 28
urea 28
CAT 28
CAT 28
Asp 26
ABA 26
TBP 25
ACS 25
TBP 25
ACS 25
ADP 24
ADP 23
ADP 23
ammonia 23
PEG 23
nitric oxide 23
cadmium 23
CO2 23
valine 22
GTP 22
PAS 21
ABA 21
Phytol 19
Phytol 19
Ile 18
nicotinamide 18
TNF 17
TEM 17
H2O2 17
NAD 17
alcohol dehydrogenase 17
SDS 17
CoA 17
GMP 17
acetic acid 16
isoleucine 15
isoleucine 15
COS 15
cobalt 14
barium 14
pyrimidine 14
THP 14
GSH 13
asparagine 13
GSH 13
NADPH 13
TAR 13
Gly 13
NADP 13
adenosylmethionine 13
pyrimidine 13
NAD 13
MDA 13
NADPH 13
Ethylene 12
FAD 12
pentose 12
pentose 12
pentose 12
pentose 12
GA3 11
aldehyde 11
PEG 11
Histone 11
PMA 11
PHB 11
MAP 10
potassium 10
methanol 10
Heme 10
nickel 10
aspartic acid 10
2-oxoglutarate 10
AAA 10
NADH 10
THP 10
Insulin 10
Alanine 9
Thyroid 9
cyanide 9
molybdenum 9
manganese 9
phosphorus 9
glutamic acid 9
aspartic acid 9
aspartic acid 9
Leucine 9
aspartic acid 9
PTS 9
MEK 9
C2H2 8
toluene 8
protocatechuate 8
PMA 8
TPA 8
DMS 8
CAM 8
phenazine 8
TPA 8
aldehyde 8
Tetracycline 7
Serine 7
chromate 7
benzene 7
gamma-aminobutyric acid 7
mercury 7
more...