Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P51532 (
transcriptional activator
)
6,546
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
To increase phenylpropanoid constituents and energy content in the versatile C
4
grass sorghum (
Sorghum bicolor
[L.] Moench), sorghum genes for proteins related to monolignol biosynthesis were overexpressed: SbMyb60 (
transcriptional activator
), SbPAL (phenylalanine ammonia lyase), SbCCoAOMT (caffeoyl coenzyme A [CoA] 3-
O
-methyltransferase), Bmr2 (
4-coumarate:CoA ligase
), and SbC3H (coumaroyl shikimate 3-hydroxylase). Overexpression lines were evaluated for responses to stalk pathogens under greenhouse and field conditions. Greenhouse-grown plants were inoculated with
Fusarium thapsinum
(Fusarium stalk rot) and
Macrophomina phaseolina
(charcoal rot), which cause yield-reducing diseases.
F. thapsinum
-inoculated overexpression plants had mean lesion lengths not significantly different than wild-type, except for significantly smaller lesions on two of three
SbMyb60
and one of two
SbCCoAOMT
lines.
M. phaseolina
-inoculated overexpression lines had lesions not significantly different from wild-type except one
SbPAL
line (of two lines studied) with mean lesion lengths significantly larger. Field-grown
SbMyb60
and
SbCCoAOMT
overexpression plants were inoculated with
F. thapsinum
. Mean lesions of
SbMyb60
lines were similar to wild-type, but one
SbCCoAOMT
had larger lesions, whereas the other line was not significantly different than wild-type. Because overexpression of
SbMyb60
,
Bmr2
, or
SbC3H
may not render sorghum more susceptible to stalk rots, these lines may provide sources for development of sorghum with increased phenylpropanoid concentrations.
...
PMID:Response of Sorghum Enhanced in Monolignol Biosynthesis to Stalk Rot Pathogens. 3121 51
