Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Vascular diseases are the main reason for morbidity and mortality worldwide. As we known, the earlier phase of vascular diseases is endothelial dysfunction in humans. The endothelial tissues play an important role in inflammation, coagulation, and angiogenesis, via the organizing of ligand-receptor associations and the various mediators' secretion. We can use many inflammatory non-invasive tests (flow-mediated dilatation, epicedial fat thickness, carotid-intima media thickness, arterial stiffness and ankle-brachial index) for assessing the endothelial function. In addition, many biomarkers (ischemia modified albumin, pentraxin-3, E-selectin, angiopoietin, endothelial cell specific molecule 1, asymmetrical dimethylarginine, von willebrand factor, endothelial microparticles and endothelial progenitor cells can be used to evaluate endothelial dysfunction. We have focused on the relation between endothelial dysfunction and inflammatory markers of vascular disease in this review.
 ...
PMID:Endothelial dysfunction and inflammatory markers of vascular disease. 3231 94