Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A novel host-guest metal-organic compound with both chiral hydrophilic and achiral hydrophobic channels has been obtained through the reaction of Cd(II) ion and a versatile asymmetrical ligand of H(4)bptc (H(4)bptc = 1,1'-biphenyl-2,2',3,3'-tetracarboxylic acid) based on hydro(solvo)thermal reactions.
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PMID:Coexistence of chiral hydrophilic and achiral hydrophobic channels in one multi-helical-array metal-organic framework incorporating helical water cluster chains. 1714 6

Carbon-11 labeled isocyanates are efficiently prepared by dehydration of [(11) C]carbamate salts, which in turn are easily formed from cyclotron-produced [(11) C]CO(2) and amines in the presence of a CO(2) fixation agent. The [(11) C]isocyanates are useful radiosynthons for the synthesis of a variety of [carbonyl-(11) C]-labeled asymmetrical ureas and carbamate esters. The method is well suited to incorporate any isotope of carbon, and is especially useful for positron emission tomography (PET) radiotracers for in vivo imaging. This is demonstrated by using the method to make [carbonyl-(11) C]-6-hydroxy-[1,1'-biphenyl]-3-yl cyclohexylcarbamate which is a novel radiotracer for PET imaging of fatty acid amide hydrolase.
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PMID:Synthesis and application of isocyanates radiolabeled with carbon-11. 2120 22