Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P50583 (
asymmetrical
)
12,197
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The binding of
asymmetrical
and optically pure tridentate ligands (
L
=
1(
S
)
and
1(
R
)
) containing one carboxylic group and
2-naphthyl
as an antenna to lanthanide ions (
M
= La(iii) and Eu(iii)) was studied in CH
3
CN, showing the successive formation of
M:L
,
M:L
2
and
M:L
3
stoichiometric species in solution. The europium complexes
EuL
3
were also synthesised, structurally characterised and their photophysical properties probed in CH
3
OH and CH
3
CN. The changes in the chiroptical properties of both
1(
S
)
and
1(
R
)
were used (by circular dichroism (CD) spectroscopy) to monitor the formation of these chiral self-assemblies in solution. While circularly polarised luminescence (CPL) showed the formation of
Eu(1(
S
))
3
and
Eu(1(
R
))
3
as enantiomers, with high luminescence dissymmetry factors (
g
lum
), fitting the CD changes allowed for binding constants to be determined that were comparable to those seen in the analyses of absorbance and luminescence changes.
...
PMID:The application of chiroptical spectroscopy (circular dichroism) in quantifying binding events in lanthanide directed synthesis of chiral luminescent self-assembly structures. 2893 3
