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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of asymmetrical tension on the vibratory pattern of the vocal cords were studied in two kinds of experiments: 1) high speed motion picture photography of artificial voice production in excised canine and human larynges, and 2) computer synthesis of voice and vocal cord vibration via a theoretical model incorporating the physiological parameters required for phonation. In both approaches the asymmetrically tensed vocal cords consistently vibrated in three distinct modes which depend partly on the rest positions of the vocal cords; Type I. For rest positions at or near closure, the two cords vibrate at the same frequency with glottal closure every period, and with tense cord preceding the lax one in phase and with the line of contact moving toward the tenser cord during the closed phase. The voice produced is not hoarse; Type II. For wider rest positions glottal closure occurs irregularly, the vibrations become complex and less periodic, and the voice becomes hoarse; Type III. The glottis never closes and the vibrations become more periodic with reduced amplitude. Supplementary stroboscopic observations suggest a precedure for diagnosing tension asymmetry and the implications for surgical treatment for disorders of vocal pitch are discussed.
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PMID:Clinical significance of asymmetrical vocal cord tension. 83 73

This study investigated the use of the Spanish subjunctive in bilingual children with and without specific language impairments (SLI). Using an elicited production task, we examined: (1) the potential of the subjunctive as a grammatical marker of SLI in Spanish-English bilingual children, (2) the extent to which degree of bilingualism affects performance, and (3) the specific patterns of errors across groups. The participants in this study were 16 children with SLI and 16 typically developing children (TD) matched on age, English language proficiency, and mother's education level. Bilingual children were selected based on their English proficiency and were classified either as Spanish-dominant children with intermediate English proficiency (asymmetrical bilinguals, AsyBi), or near-balanced bilinguals (BalBi). A completion task elicited the subjunctive in complement, purpose and temporal clauses. Results suggest that (1) level of bilingual proficiency, language clinical status, and age predicted of the accurate production of the subjunctive, (2) temporal clauses might have a better potential to discriminate between TD children and children with SLI in bilingual settings, and (3) tense underspecification errors were common in children with SLI. This study provides general support for grammatically targeted approaches to assessment in bilingual populations, and for theoretical approaches that link SLI to tense deficits.
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PMID:The Complexity of the Spanish Subjunctive in Bilingual Children with SLI. 2939 81

According to a prominent account of inflectional encoding (Pinker, 1999; Pinker & Ullman, 2002b), regular forms are encoded by a rule-governed combination of stems and affixes, whereas irregular forms are retrieved from memory while inhibiting rule application. Sahin, Pinker, and Halgren (2006) suggested that this concerns a domain-general mechanism. Previous research on domain-general inhibition has shown that when switching between tasks, languages, or phrase types, an asymmetrical switch cost is obtained, which has been attributed to overcoming previous inhibition of the predominant response. If generating an irregular form involves rule inhibition, then switching from an irregular to a regular form should require overcoming previous inhibition and delay responding. We tested this in three experiments on producing the past tense in Dutch. We observed that an asymmetrical switch cost is obtained when switching between inflecting and reading verbs, but not when switching between encoding irregular and regular forms. These results suggest that the production of irregular forms does not involve the type of domain-general inhibition involved in switching between tasks, languages, or phrase types.
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PMID:The role of domain-general inhibition in inflectional encoding: Producing the past tense. 3215 54