Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 63-year-old man admitted to our hospital because of dyspnea and inspiratory stridor. The X-ray computed tomography and angiogram revealed tracheal stenosis due to compression by aortic arch aneurysm of retroesophageal right aortic arch. His face was congenitally asymmetrical, and he also showed anotia, and meatal atresia. In the operation, we approached the aneurysm via median sternotomy and left thoracotomy by the 3rd intercostal space, and found atretic left aortic arch in front of trachea. So, operative diagnosis was Edwards Ib complete vascular ring associated with right aortic arch aneurysm. The aneurysm was incised and the arch and its branches were reconstructed with vascular prosthesis under ECC using selective cerebral perfusion. Postoperatively, until 5th postoperative day his condition was uneventful, and he was neurologically almost normal. But on the 5th postoperative day, his hemodynamics suddenly deteriorated because of severe pneumonia and septicemia. On the 6th postoperative day, he died in spite of earnest resuscitation. We could not find any previous reports about this rare combination of diseases.
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PMID:[A case report of tracheal stenosis due to true aortic arch aneurysm of retroesophageal right aortic arch associated with so called vascular ring-facial syndrome]. 756 21

A double aortic arch is described in an 8-week-old female Siamese cat. In this case a vascular ring anomaly consistent with a double aortic arch is described in a cat. Stridor and dysphagia were noted in the cat. Radiography showed an esophageal dilation, with constriction at the fifth intercostal space. At necropsy, the esophagus and trachea were constricted at the base of the heart. The cause of the constriction of both the esophagus and trachea was a vascular ring formed by well-developed right and left aortic arches. The ascending aorta divided into two asymmetrical arches. The right aortic arch was larger than the left. The origin of the major arteries from the aortic arches were anomalous.
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PMID:Double aortic arch in a Siamese cat. 1042 Nov 2

To evaluate the role of MR imaging in patients with laryngoscleroma. We retrospectively reviewed the MR imaging of 14 patients (11 female, 3 male with mean age of 31 years) with pathologically proven laryngoscleroma. They presented with dysphonia (n = 12), stridor (n = 8) and airway obstruction (n = 4). They underwent T1- and T2-weighted MR images and post contrast study after injection of 0.1 mmol Gd/DTPA. Laryngoscleroma was seen in the subglottic (n = 13) and supraglottic (n = 1) regions. Laryngoscleroma at granulomatous stage (n = 6) appeared as diffuse circumferential soft tissue mass with high (n = 4) or mixed (n = 2) signal intensity on T2-weighted images with homogenous (n = 4) and inhomogeneous (n = 2) pattern of contrast enhancement. At fibrotic stage (n = 8), laryngoscleroma was seen as diffuse asymmetrical circumferential thickening of the subglottic region with low signal intensity on T2-weighted images and mild contrast enhancement. Subglottic lesions encircled the subglottic region with marked (n = 5) and mild (n = 9) narrowing of the airway with variable degree of extension into the trachea in three patients. There was diffuse thickening of the epiglottis, aryepiglottic folds in one patient with supraglottic scleroma. MR imaging is a non-invasive imaging modality for accurate localization, extension and staging of laryngoscleroma. These data is important for treatment planning.
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PMID:Role of MR imaging in laryngoscleroma. 2312 82

Follicular lymphomas (FL) are among the most common non-Hodgkin's lymphoma (NHL) in adults. However, they are rare in children making up less than 3% of paediatric NHL cases. They occur most commonly in the head and neck region, lymph nodes or tonsils, with occasional extra-nodal occurrences. Distinction of FL from potentially clonal but, reactive follicular hyperplasia is important. We report a case of a 6-year-old male child presenting with night stridor since 6 months. Clinical examination revealed asymmetrical enlargement of the left tonsil. Routine left tonsillectomy was performed and the specimen was sent for histopathological examination. Diagnosis of follicular lymphoma was made on histopathological examination and further confirmed by immunohistochemistry.
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PMID:Tonsillar follicular lymphoma in a child. 2318 42