Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report the case of a 65-year-old patient with a 15-year history of intermittent asymmetrical oligoarthritis, who subsequently developed splenomegaly, lymphadenopathy, and episodic leucopenia and thrombocytopaenia. Investigations revealed hairy cell leukaemia, and 'hairy cells' were detected in the synovial fluid. No other cause for this arthritis was found, and we consider the blood dyscrasia to be the likely cause. This case demonstrates a hitherto unreported association between arthritis and hairy cell leukaemia.
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PMID:Arthritis associated with hairy cell leukaemia. 709 43

We report the case of a patient who complained of arthralgias and arthritis 1 month before the onset of fever or other signs of infective endocarditis. In 2 months she developed an additive, asymmetrical polyarthritis with fever (febrile polyarthritis). Splenomegaly was present. Two-dimensional echocardiography showed no vegetations or other findings suggesting endocardial involvement. Initially, four blood cultures showed no microorganisms, then six of nine subsequent blood cultures grew highly gentamicin-resistant Enterococcus faecalis.
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PMID:Infective endocarditis presenting as polyarthritis. 989 Jun 83