Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A Norwegian family with asymmetrical scapuloperoneal atrophy is described. Chronic, aching shoulder pain, slight proximal and distal sensory dysfunction, and atrophy of the extensor digitorum brevis muscle occurred in some individuals. The proband had slightly impaired sensory conduction velocity, and his father exhibited impaired position sense and a vibration threshold asymmetry. EMG and muscle biopsy findings were equivocal. The syndrome is probably of neurogenic origin. It may be classified as a variant of Davidenkow's syndrome.
 ...
PMID:Sensory signs and symptoms in scapuloperoneal atrophy: a report of a family. 406 60

A 70-year-old woman with squamous cell carcinoma of the lung and chronic lymphocytic leukemia/small lymphocytic lymphoma underwent PET/CT for initial staging. There was avid focal asymmetrical uptake at the left shoulder, concerning for metastasis. Magnetic resonance imaging performed for further evaluation showed an enhancing soft tissue process at the rotator interval. Clinical notes indicated a 6-month history of progressive left shoulder pain and limited range of motion. The magnetic resonance imaging appearance and patient's symptoms were characteristic of adhesive capsulitis. We describe a new location of benign FDG avidity at the rotator interval due to adhesive capsulitis that can mimic neoplasm.
...
PMID:Adhesive capsulitis mimicking metastasis on 18F-FDG-PET/CT. 2499 85

A 54-year-old man presented to the emergency department with a 4-week history of right shoulder pain radiating down his arm, with some associated sensory loss. Further questioning and examination in the department revealed a classical Horner's syndrome; miosis, partial ptosis and hemifacial anhidrosis. An initial chest X-ray was deemed to be unremarkable; however, further review by a radiologist noted asymmetrical right apical thickening. A subsequent high-resolution CT scan of the chest revealed a right-sided Pancoast tumour. This case highlights the importance of a thorough history and examination in identifying a rare cause of shoulder and/or back pain.
 ...
PMID:Pancoast tumour presenting as shoulder pain with Horner's syndrome. 3068 61