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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Infant positional plagiocephaly, a cranial molding deformity expressed by asymmetrical head shape, is on the rise. The increase correlates with the recommendation by the American Academy of Pediatrics that infants be placed on their backs to sleep to reduce the risk of sudden infant death syndrome. The majority of misshapen heads develop because infants are placed to sleep in the same supine position, without head rotation. Infant molding deformities will generally improve with repositioning and cranial growth, but permanent deformation can occur, especially without early treatment. This article informs pediatric practitioners about positional plagiocephaly, offers preventative and treatment interventions, and reviews treatment options.
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PMID:Infant cranial molding deformation and sleep position: implications for primary care. 1069 81

Positional plagiocephaly is a deformation resulting from intrauterine constraint or postnatal positioning leading to asymmetrical cranial growth. There has been a steady increase in referrals for positional plagiocephaly following the release of the American Academy of Pediatrics recommendation of supine infant sleeping position to prevent Sudden Infant Death Syndrome (SIDS) in 1992, largely because of poor parent education on the risks of prolonged occipital pressures. While this deformity is fairly easy to manage when diagnosed early, treatment can become more difficult and complicated with prolonged course. Because of this, it is essential that primary care physicians and parents be educated on recognition of positional plagiocephaly, prevention strategies, and treatment options. In milder cases, where diagnosis is made early, the deformation can be managed by stretching exercises and regular prone positioning, while in more severe cases molding helmets may be needed. Following appropriate treatment, success rates for acceptable cranial shape may be as high as 92%.
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PMID:Positional plagiocephaly: pathogenesis, diagnosis, and management. 1670 Apr 33