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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A model taking into account the cyclic character of respiration in humans is developed using two classical simplifications: CO2 is the only respiratory gas involved; and respiration is regulated only by a CO2 linear controller. The model is used to investigate two important clinical aspects of respiratory disease: asymmetrical ventilation and periodic breathing. We show that asymmetry in ventilation significantly influences the time course of the CO2 partial pressure in the expired alveolar air at the mouth and the elimination of CO2 through the lungs. Furthermore, the CO2 controller delay plays a major role in periodic breathing.
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PMID:Cyclic model of respiration applied to asymmetrical ventilation and periodic breathing. 832 Sep 86

This paper aims to explain the results of an observational population study that was carried out between 1991 and 1995 in six regions (departments) in France. The study was to assess the relationship between temperature and mortality in a few areas of France that offer widely varying climatic conditions and lifestyles, to determine their thermal optimum, defined as a 3 degrees C temperature band with the lowest mortality rate in each area, and then to compare the mortality rates from this baseline band with temperatures above and below the baseline. The study period was selected because it did not include extreme cold or hot events such as a heatwave. Data on daily deaths from each department were first used to examine the entire population and then to examine men, women, various age groups and various causes of death (respiratory disease, stroke, ischaemic heart disease, other disease of the circulatory system, and all other causes excluding violent deaths). Mean temperatures were provided by the National Weather Service. The results depicted an asymmetrical V- or U-shaped relationship between mortality and temperature, with a thermal optimum lower for the elderly, and generally lower for women than for men except in Paris. The relationship was also different depending on the cause of death. In all cases, more evidence was collected showing that cold weather was more deadly than hot weather, and it would now be interesting to enlarge the study to include years with cold spells and heatwaves. Furthermore, the results obtained could be of great use in estimating weather-related mortality as a consequence of future climate-change scenarios.
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PMID:Temperature-related mortality in France, a comparison between regions with different climates from the perspective of global warming. 1684 88

[Purpose] Some patients with respiratory disease exhibit asymmetrical movement of the thorax. The purpose of this study was to investigate the relationship of thoracic configuration with changes in thoracic volume in 13 sedentary healthy men. [Subjects and Methods] In upright sitting, 84 reflective markers were placed on the anterior and posterior aspects of the trunk to record thoracic volume during quiet and volitional deep breathing. Using a three-dimensional motion analyzer, the difference in volume within the upper and lower hemithoraces was measured. For calculation of the thoracic volume six imaginary hexahedra were visualized for the upper and lower thorax using four reflective markers for each on the anterior and posterior aspects of the thorax. Each hexahedron was then divided into three imaginary triangular pyramids to calculate positional vectors. Finally, the volume for both the hexahedra and triangular pyramids was calculated. Four thoracic volumes were obtained. [Results] The findings showed that the left upper and right lower hemithorax yielded significantly larger thoracic volumes. [Conclusion] In conclusion the left upper and right lower hemithoraces were found to expand more than their corresponding sides. Understanding the characteristics of thoracic excursion during quiet and volitional deep breathing could be of value in assessment and instruction of breathing techniques to patients.
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PMID:The relationship between thoracic configuration and changes in volumes of hemithoraces in upright sitting. 2794 50