Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors describe a systematic approach to plain-film diagnosis of joint disease. The major radiologic criteria--soft-tissue swelling, joint-space narrowing, bone erosion, bone sclerosis and osteophytosis, and chondrocalcinosis--are considered first. Assessing the involvement of the minor criteria of joint disease--soft-tissue atrophy or calcification, malalignment, osteoporosis, abnormal growth, intra-articular bony ankylosis, bone fragmentation, periostitis, subperiosteal resorption or acro-osteolysis--narrows the probabilities to the more likely diagnoses. Further analysis includes the distribution of joint injury, whether mono- or polyarticular, symmetrical or asymmetrical. Added to clinical information, this approach leads to a specific or refined differential diagnosis.
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PMID:Plain-film diagnosis of joint disease. 203 62

Periostitis ossificans (PO) is a type of osteomyelitis stemming from an odontogenic infection, generally found in children and adolescents, and often leads to the loss of the involved tooth. This case presents a less invasive alternative for the treatment of PO. A 10-year-old patient presented with an asymmetrical increase in the left side of the mandible. Tooth 36 exhibited pulp necrosis and incomplete root formation. Radiographically, the bone in the region had the appearance of the layers of an onion. Computed tomography indicated periosteal bone proliferation in the region of the ramus and angle of the mandible adjacent to the vestibular cortical bone. Therapy involved root canal preparation and intracanal medication with calcium hydroxide in tooth 36. Complete remission of the condition occurred within 14 months. In conclusion, endodontic intervention is a less invasive alternative and should be considered to minimize the negative impact of tooth loss in children.
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PMID:Periostitis ossificans in a 10-year-old child. 3217 34