Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P50583 (
asymmetrical
)
12,197
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This article describes a form of localized aggressive periodontitis (LAP) in young multiparous women and denotes this form of periodontitis as localized aggressive multiparous periodontitis (LAMP). The authors retrospectively reviewed six cases of LAP in healthy multiparous women who were followed clinically for more than five years, examining clinical histories, clinical findings, and radiographic features. Age, race, gender, parity, location of attachment loss, rate of attachment loss, and symptoms were recorded. LAMP is characterized by
asymmetrical
attachment loss along the distal proximal area of the maxillary and/or mandibular first permanent molars in multiparous females with a median age of 27. The mean annual rate of attachment loss in the maxillary first molars was calculated at 0.5 mm. LAMP progresses to involve the mandibular incisors but, unlike LAP, appears to spare the maxillary incisors. The authors suggest that LAMP is a recognizable
periodontal disease
that can be diagnosed in young, multiparous females via clinical history, periodontal examination, and radiographs. This study presents potential pathogenic pathways and suggests a possible answer to the paradox of why aging women become more edentulous than men despite better overall dental care.
...
PMID:Localized aggressive multiparous periodontitis: a newly documented entity. 2190 69
The esthetic rehabilitation of advanced periodontal cases remains a challenge, despite the numerous advances in treatment of periodontitis and regenerative therapies. Whilst understanding of periodontal diseases deepens with advances in cell biology, cell signaling, and genomic research, the restoration of the gingival tissues to anatomical norms remains a considerable challenge in advanced cases. The improvements in diagnosis and treatment of disease certainly enable successful management of disease and stabilization of the compromised and failing dentition. Nonetheless, effective "esthetic" rehabilitation of patients with advanced disease affecting teeth in the esthetic zone, where significant
asymmetrical
bone loss and tissue recession are present, still constitutes a significant dilemma. An interdisciplinary approach involving vertical augmentation of bone and soft tissues by means of orthodontic extrusion of severely compromised periodontally involved teeth to reconstitute esthetics, as well as ideal bone and soft tissue volume prior to immediate implant placement and restoration, may be a particularly useful treatment option in patients suffering advanced
periodontal disease
with
asymmetrical
bone and tissue loss in the esthetic zone. This paper discusses the concepts and illustrates its use in two complex and demanding cases.
...
PMID:Rehabilitation of esthetics in advanced periodontal cases using orthodontics for vertical hard and soft tissue regeneration prior to implants - a report of 2 challenging cases treated with an interdisciplinary approach. 2223 23