Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50583 (asymmetrical)
 12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The prenatal diagnosis of hydrocephalus is described in 11 cases between 17 and 21 weeks using two sonographic criteria. These sonographic findings involve the asymmetrical appearance of the choroid plexus and the size and configuration of the anterior horns of the lateral ventricles. We have found that these criteria can accurately diagnose fetal hydrocephalus in the first half of the second trimester.
 ...
PMID:The diagnosis of fetal hydrocephalus prior to 22 weeks. 313 60

A case of asymmetrical hydrocephalus complicating the surgical evacuation of a subdural haematoma is reported.
 ...
PMID:Asymmetrical hydrocephalus following evacuation of a subdural haematoma. 326 47

A rhesus monkey fetus was examined by ultrasound at 110, 111, and 113 gestational days (GD) and showed features suggestive of Amniotic Band Syndrome (ABS). These included an unusual craniofacial configuration, cortical distortion, asymmetrical hydrocephalus, a right occipital porencephalic cyst, and hydropic membranes with several free strands attached to the fetal head, neck, and scapular regions. The fetus remained fixed in the same position with the head retroflexed during each consecutive exam. A hysterotomy was performed and ABS was confirmed.
 ...
PMID:Amniotic band syndrome in a rhesus monkey: a case report. 332 Mar 75

Eight patients representing visual field defects associated with hydrocephalus are reviewed. Seven cases had aqueductal stenosis and one had congenital communicating hydrocephalus. We found five cases of defects in visual field typical of a chiasmal or optic nerve lesion: (1) inferior altitudinal hemianopia with inferior nasal quadrantanopia in the opposite eye; (2) inferior binasal quadrantanopia; (3) unilateral inferior nasal depression; (4) unilateral temporal defect; (5) bilateral central scotoma. In these cases CT demonstrated moderate or marked symmetrical dilatation of the third and lateral ventricles. Four out of five cases showed bulging of the third ventricle anteriorly into the sella turcica on CT or ventriculography. Other three patients had incongruous homonymous hemianopia. Characteristic asymmetrical dilatation of the lateral ventricles was noted in all three cases. The more enlarged lateral ventricles were ipsilateral with the affected visual pathways. The sites of lesion responsible for these field defects seemed to be optic tract in one case and optic radiation in two cases. Ventriculoperitoneal shunt was placed in five out of seven cases. Impaired visual field improved in three patients after shunt insertion. A 28-year-old female who had history of blurred vision fos 14 days showed improvement in visual acuity and field when the enlarged ventricles became slit-like by shunting. In the other two patients defects in visual fields improved in spite of consistent ventriculomegaly. These facts suggested that not only the mechanical forces with distended third ventricle but also increased intracranial pressure played an important role in producing visual field defects in hydrocephalic patients.
 ...
PMID:[Visual field defects in hydrocephalus]. 387 34

A study is presented based on CT scans, using advanced computer techniques, to determine brain volume in a representative sample of sixteen subjects, with treated and untreated hydrocephalus, whose ventricle size varied from normal to extreme and from symmetrical to grossly asymmetrical dilatation. The calculations take into account the maximal head circumference at the time of the CT scans and the results are correlated with the patients' intellectual and neurological conditions.
 ...
PMID:Brain and ventricular volume in hydrocephalus. 652 6

A 30-year-old multigravida woman was admitted to the obstetrical unit in the third trimester of gestation, because of a large-for-date uterus. Repeated ultrasonic examinations over a 2-week period revealed an increase in biparietal diameter far too large to be normal. This progressive asymmetrical hydrocephalus was diagnosed as caused by an intracranial space-occupying lesion in the middle cranial fossa. Because of the only minimal thickness of the cerebral cortex prognosis was judged so poor, that labor was induced. A stillborn female infant was delivered vaginally after an ultrasonically guided transabdominal and later transcervical encephalocentesis. Autopsy revealed hydrocephalus and section through the fixed brain showed that the mentioned mass was an undifferentiated meningeal sarcoma that filled the left middle cranial fossa. Microscopically the sarcoma was invading the brain tissue. Definitions of the term "congenital brain-tumors" vary among authors. "Congenital" can be interpreted as "derived from embryonal tissue" or as "originating in utero". Congenital intracranial neoplasms are very rare. Antenatally intracranial tumors have been reviewed by Wells, Solitare and Farwell. Only a few cases of congenital brain tumors arising in the meninges have been reported in these reviews. The genesis of the tumor is explained as derived from multipotential cells. The undifferentiated type of a meningeal sarcoma has a poor prognosis. Most meningeal sarcoma present with progressive hydrocephalus.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:Congenital meningeal sarcoma--a case report. 664 19

The radiological and clinical features of 90 histologically verified intraventricular masses were reviewed. Computed tomography (CT) and plain X-rays were available in all and angiograms in over half the cases. The localisation, effects on the adjacent brain substance and the presence and degree of hydrocephalus was evident on CT. Two-thirds of colloid cysts presented as pathognomonic anterior third ventricular hyperdense masses and the other third were isodense; an alternative diagnosis should be considered for low density masses in this situation. Plexus papillomas and carcinomas mainly involved the trigone and body of a lateral ventricle of young children and caused asymmetrical hydrocephalus; the third ventricle was occasionally affected also in children and the fourth ventricle more frequently and usually in adults. Two-thirds were hyperdense, one-third of mixed or lower density. The meningiomas were dense trigonal tumours of adults generally arising in the choroid plexus, but two tentorial meningiomas passed through the choroidal fissure and caused a predominantly intraventricular mass. Gliomas frequently thickened the septum and generally involved the frontal segments of the lateral ventricles. They may be supplied by perforating as well as by the choroidal arteries, which supply most other vascularised masses within the ventricles. Only 10% of our cases did not fall into one of the former categories; these included low density non-enhancing dermoid or epidermoid tumours and higher density enhancing metastatic or angiomatous masses.
 ...
PMID:Diagnosis of masses presenting within the ventricles on computed tomography. 685 76

Ventriculitis developed suddenly in a patient with an undiagnosed abscess and was accompanied by obtundation, fever, meningismus, and hemiplegia. Aspiration of a streptococcal thalamic abscess and high doses of intravenous penicillin produced marked improvement. Increasing dysphasia 5 weeks later was accompanied by ventricular dilatation, most marked on the left, with no evidence of recurrent abscess. The left foramen of Monro was demonstrably patent. Shunting relieved the symptoms of aphasia; they recurred with one episode of malfunction of the shunt. This case lends support to the belief that parenchymal characteristics are important in hydrocephalus and demonstrates how asymmetrical ventricular dilatation can produce focal symptoms.
 ...
PMID:Asymmetrical hydrocephalus following ventriculitis from rupture of a thalamic abscess. 685 81

Unwanted results of shunting for hydrocephalus include slit and asymmetrical ventricles and the conversion of communicating hydrocephalus to noncommunicating hydrocephalus. Evidence suggests this may be due to a mismatch between the pressure/flow performance characteristics of the shunt valve and the pathologic hydrodynamics of the ventricular cerebrospinal fluid. Commercially available shunts are currently tested using a steady-state pressure/flow method. We have utilized a bench testing method which incorporates pulsed flow and varying compliance. Results indicate that with minimal compliance in the system, opening and closing pressures differ markedly in value with pulsed flow as compared to steady-state testing. The greater the compliance the less deviation was noted. It is recommended more effort be made to understand the value of matching pressure/flow characteristics of valve to the individual hydrocephalic state.
 ...
PMID:Testing the hydrocephalus shunt valve. 688 24

Cysticercosis cerebri is a rare neurological diagnosis, which is usually made at the time of operation or at autopsy. Few cases have been reported in North America, and these were usually found in immigrants and in domestic travelers who lived in infested countries. Cysticercosis cerebri is classically divided into four general types: 1) intraparenchymal, 2) basilar cisternal, 3) ventricular, and 4) diffuse cerebral. We are presenting a unique case of solitary ventricular cysticercosis occluding the foramen of Monro, and producing an asymmetrical obstructive hydrocephalus.
 ...
PMID:Cysticercosis cerebri occluding the foramen of Monro. 696 97


<< Previous 1 2 3 4 5 Next >>