Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P50583 (asymmetrical)
12,197 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To correct compensatory head turn in twelve cases with congenital nystagmus, they were classified into two types according to the relative visual lines of both eyes to each other with respect to the sagittal axis of the head or the median plane of the body. One was termed the symmetrical pattern and the other was termed the asymmetrical pattern. In cases of the symmetrical pattern, a neutral zone exists in which the dominant eye in in the adducted position of gaze with esotropia and in the abducted position of gaze with exotropia. However, in the case of the asymmetrical pattern the neutral zone of the dominant eye is located in the abducted position of gaze with esotropia and in the abducted position of gaze with exotropia. Surgery was performed by shifting the dominant eye to the direction of the sagittal axis of the head in accordance with the degree of ocular deviation in the primary position. In asymmetrical pattern cares, both eyes were surgically shifted in parallel to the direction of the sagittal axis of the head without regard to the types of strabismus. The operation was based on the degree of compensatory head turn. We compared the surgical results the two types. In symmetrical cases, decreasing strabismus was disappointing compared to the head turn, while in asymmetrical cases decreasing head turn was disappointing as compared to strabismus. From these results surgery should be confined to the dominant eye in symmetrical cases, taking as the basis for operation the degree of head turn and not the ocular deviation.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Surgical treatment of torticollis in cases of congenital nystagmus with strabismus]. 261 Jan 64

Our surgical treatment of the A and V phenomena consists of a systematic combination of oblique and horizontal muscle surgery. The oblique muscles are desagittalized: the plane of action of the muscle is displaced forwards so that its angle with the visual axis enlarges. The vertical action of the oblique muscle is thus reduced in favour of the torsional action. This desagittalization is always performed bilaterally and combined with a bilateral recession of a rectus muscle: the medial rectus muscles in cases of esotropia and the lateral rectus muscles in cases of exotropia. A real vertical deviation (RVD), if present, is treated by asymmetrical oblique muscle surgery or by the weakening of a vertical rectus muscle. In cases of under- or overcorrection a remaining diagonal and vertical deviation is carefully searched for and dealt with. In addition, a horizontal undercorrection is treated by placing a secondary loop on the already recessed medial rectus muscle, and a horizontal overcorrection is treated by weakening both lateral rectus muscles.
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PMID:Surgical treatment of the A and V phenomena. 696 55

Surgical results after symmetrical and asymmetrical surgery performed by the same surgeon (M.S.) as initial procedure for basic intermittent exotropia were retrospectively analysed in 55 young patients. Twenty-five patients underwent unilateral recess-resect surgery on the non-fixating eye (Groupe 1) and 30 patients bilateral lateral rectus recessions (Group 2). The average age at surgery was 6.5 yrs (range: 2-18). The average post-operative follow-up was 2.81 yrs (range: 0.50-8 yrs), (p = 0.143). Sensory fusion was assessed by the Bagolini straited glasses and/or the Worth test and stereopsis by either the TNO and/or Lang stereoacuity test prior and after surgery. Prior to surgery, 84% of the patients had reached isoacuity. Ocular motility was normal in all patients. The average size of preoperative exotropia measured by prism and alternate cover test was 28 PD (SD = 5) for both Groups. In the immediate postoperative period, 53% of the patients were overcorrected without any statistically significant difference between the 2 groups (p = 0.053). Nine (16%) patients had a "mixed" deviation (from eso- to exo depending of the fixation distance), 8 (15%) patients were orthophoric (20% in Group 1 vs 10% in Group 2) and 9 (16%) patients were undercorrected (12% in Group 1 vs 20% in Group 2). The results at last exam, were similar between the 2 Groups; good or fair alignment was achieved in 29 (53%) patients (p = 0.512); 23 (42%) patients had still X(T) (p = 0.829) and 3 (5%) patients were overcorrected. We concluded that even if the immediate postoperative results seem better with asymmetrical surgery, in the long-term there is no significant difference between the two surgical procedures.
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PMID:[Symmetric or asymmetric surgery for basic intermittent exotropia]. 981 Jan 4

We investigated the clinical factors affecting the development of consecutive exotropia following esotropia surgery. The development period of consecutive exotropia, amblyopia and limitation of adduction were evaluated in 89 patients with primary esotropia that changed to consecutive exotropia after surgery. In the presence of deep amblyopia, consecutive exotropia developed earlier. When two horizontal muscles were operated, limitation of adduction was more frequent in symmetrical rather than asymmetrical surgical procedure. Since consecutive exotropia may develop many years after esotropia surgery, a long-term follow-up period in patients without consecutive exotropia in the early postoperative period is advised.
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PMID:Consecutive exotropia following strabismus surgery. 1220 26