Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50502 (Hip)
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Human Gene/Protein
Hip 12.2
EMILIN3 10.6
CCDC91 10.2
METRNL 10.2
hsp70-interacting protein 9.8
BAG-5 9.6
STCH 9.3
BAG-2 9.2
PTHR2 9.0
SODD 8.8
scythe 8.8
CILP2 8.8
SH3P7 8.8
MEK kinase 2 8.6
DDH 8.4
Hsp70-interacting protein 8.3
Ubiquilin-2 8.2
ADAMTS16 8.2
HHS 8.1
huntingtin interacting protein 8.1
DPM3 8.0
chimera 1 8.0
CHC22 7.9
chimera 2 7.9
AARS 7.9
alpha NAC 7.9
CRIP1 7.8
HIP-55 7.8
HTE 7.8
DPM synthase 7.8
BAG-1 7.7
protein phosphatase 3 7.7
CHIP 7.7
BAG5 7.6
tetratricopeptide repeat protein 7.5
STEAP1 7.5
CLS 7.5
Huntingtin-interacting protein 1 7.5
DPM2 7.5
Glycogen synthase kinase 3 beta 7.5
STIP1 7.3
cyclophilin 40 7.3
MNK 7.2
ubiquitin-protein isopeptide ligase (E3) 7.2
PES1 7.2
ubiquitin B 7.2
DACT2 7.2
RPL29 7.2
ABG 7.1
Corin 7.1
EHD3 7.1
OGN 7.1
flotillin 2 7.1
C-terminal binding protein 2 7.1
PKM2 protein 7.1
NELL-1 7.0
LRR1 7.0
UBC7 7.0
DYNC2H1 7.0
IRX1 7.0
NOF 6.9
TKR 6.9
UBE2D1 6.9
SAP18 6.9
suppressor of fused 6.8
Hsp40 6.8
GRIK4 6.8
FK506-binding protein 38 6.8
HHIP 6.8
CDON 6.7
CP protein 6.7
ribosomal protein L29 6.7
COL8A1 6.6
HspBP1 6.6
JPS 6.6
DHS 6.6
DRAL 6.6
FKBP52 6.5
DNAJA1 6.5
TRO 6.4
HIP 6.4
SLA2 6.4
mitogen-activated protein kinase 3 6.4
RNF2 6.4
PPP3CA 6.3
ST13 6.3
BONE 6.3
MO25 6.3
HOS 6.3
Tumor suppressor protein 6.3
E2 ubiquitin-conjugating enzyme 6.3
WISP3 6.3
BMD 6.3
OTA 6.3
ROM 6.2
EHD2 6.2
Angiotensin I converting enzyme 6.2
FKBP38 6.2
DCP1 6.2
TRIM22 6.2
Cam 6.2
DPM1 6.2
LARS 6.2
PSMB9 6.1
MIS 6.1
small acidic protein 6.1
STRAD 6.1
PGAM5 6.1
GIR 6.0
ADL 6.0
FKBP51 6.0
FGS 6.0
Histone H2A 6.0
DYX1C1 6.0
XAF1 5.9
HARP 5.9
GPR37 5.9
TED 5.9
STI1 5.9
lysosomal alpha-glucosidase 5.9
S100A2 5.9
p48 5.9
OTUB1 5.8
fatty acid transport protein 1 5.8
NQO1 protein 5.8
p60 5.8
Suppressor of Fused 5.7
Dsk2 5.7
CAPN3 5.7
C-RAF 5.7
SKT 5.7
CDPX2 5.7
A49 5.7
ubiquitin-conjugating enzyme E2 5.6
PIS 5.6
IRS-4 5.6
SENP3 5.6
p23 5.6
FRK 5.6
WWP1 5.6
CDO 5.6
RING1B 5.5
UbcH7 5.5
MLK 5.5
LCP 5.4
Hsp90 5.4
Dance 5.4
Br3 5.4
HSS 5.4
DTD 5.4
3B3 5.4
ubiquitin-conjugating enzyme 5.3
zinc metallopeptidase 5.3
INSL3 5.3
BEF 5.3
EOS 5.3
scavenger receptor class B type 1 5.3
E3 protein 5.3
DOCK8 5.3
kinesin light chain 5.3
more...
Disease
Benign bone tumor 12.2
Complication, infection 12.2
Pelvis 11.5
Chlorhexidine allergy 11.2
Obturator neuropathy 9.6
Obturator neuropathy 9.6
Snapping hip 9.5
Transient synovitis 9.3
Leg length discrepancy 9.2
Sciatic nerve palsy 9.0
Elbow dysplasia 8.8
Canine hip dysplasia 8.8
arthritis of the hip 8.7
coxarthrosis 8.6
Iliopsoas bursitis 8.6
Bone marrow edema syndrome 8.6
OHS 8.3
Iliotibial band syndrome 8.2
HHS 8.1
HHS 8.1
Dysostosis 8.0
Perthes disease 7.9
BFH 7.8
Protrusio acetabuli 7.8
metaphyseal dysostosis 7.6
Synovial osteochondromatosis 7.6
Lequesne 7.5
Bone and joint infections 7.4
CHARGE syndrome 7.4
Mucolipidosis 7.3
congenital dislocation of the hip 7.2
Bone marrow edema 7.0
chondrolysis 7.0
Bone fragility 7.0
LCP 7.0
Spondyloepiphyseal dysplasia tarda 6.9
Femoral neuropathy 6.9
Eccrine poroma 6.9
Hyponatremic 6.9
CLS 6.8
bursitis 6.7
Periodic fever 6.7
osteoporotic fracture 6.6
Barlow 6.6
DHS 6.6
DHS 6.5
Prosthetic joint infection 6.5
epiphysis 6.4
Septic arthritis 6.3
osteoarthritis 6.2
chondromatosis 6.2
Unicameral bone cyst 6.2
HPC1 6.1
spinal degeneration 6.0
heritable connective tissue disorder 6.0
HOS 5.9
joint effusion 5.9
BMD 5.9
Synovial chondromatosis 5.9
IgM gammopathy 5.8
epiphysiolysis 5.8
Pituitary gland 5.8
Pituitary gland 5.8
Pituitary gland 5.8
capsulitis 5.8
dysplasia 5.8
enthesopathy 5.7
background diabetic retinopathy 5.7
lumbar spondylosis 5.7
rotator cuff syndrome 5.6
osteochondromatosis 5.6
Prehypertension 5.6
Brown tumor 5.6
osteochondrodysplasia 5.6
septic arthritis 5.6
apophysitis 5.6
Localized disease 5.6
Osteoid osteoma 5.5
Androgen deficiency 5.5
HRA 5.5
Axenfeld-Rieger syndrome 5.4
Psoas abscess 5.4
spondyloepiphyseal dysplasia 5.4
infectious arthritis 5.4
osteochondritis 5.3
HSS 5.3
X-linked hydrocephalus 5.3
EOS 5.3
EOS 5.3
Freiberg 5.3
musculoskeletal infection 5.2
cerebral palsy 5.2
MCS 5.2
MCS 5.2
Metabolic bone disease 5.2
osteoporosis 5.2
Nemaline myopathy 5.2
Anus 5.2
nerve entrapment 5.2
Lower limb 5.2
HAN 5.2
Schnitzler syndrome 5.1
DTD 5.1
Tumoral calcinosis 5.1
coxitis 5.0
early disease onset 5.0
DVT 5.0
gonarthrosis 5.0
Scheuermann's disease 5.0
villonodular synovitis 5.0
Postoperative infection 5.0
sponge kidney 5.0
arthropathy 5.0
PCS 5.0
spastic diplegia 4.9
JIP 4.9
synovitis 4.9
circulatory disorder 4.9
Tumor-induced osteomalacia 4.9
FIM 4.9
Diffuse idiopathic skeletal hyperostosis 4.8
staghorn calculus 4.8
Frontal lobe 4.8
idiopathic disorder 4.8
Estrogen deficiency 4.8
disuse osteoporosis 4.8
monoarthritis 4.7
radioulnar synostosis 4.7
arthrodesis 4.7
arthritis of the knee 4.6
tendinitis 4.5
foot drop 4.5
kidney hypertrophy 4.5
pathological fracture 4.4
osteoma 4.4
Gull 4.4
fat embolism 4.4
Scheie 4.4
decubitus 4.3
jetlag 4.3
ankylosing spondylitis 4.3
collagen disease 4.3
chondromalacia 4.3
deep vein thrombosis 4.3
enthesitis 4.2
periarthritis 4.2
diplegia 4.2
Ellis-van Creveld syndrome 4.2
hereditary motor and sensory neuropathy 4.1
Best 4.1
Larsen 4.1
Spondyloarthritis 4.1
inflammatory joint disease 4.1
RSI 4.1
SMD 4.1
plantar fasciitis 4.1
Tauopathies 4.1
juvenile rheumatoid arthritis 4.1
collagen disease 4.1
complete paraplegia 4.1
more...
Symptom
clicking hip 10.2
Hip joint laxity 9.8
hip pain 9.1
groin pain 8.7
thigh pain 8.7
Sensory ataxia 8.1
Ankle stiffness 8.0
Dribbling 7.9
pain in the buttock 7.5
Sore 7.3
Pain at rest 6.8
musculoskeletal disability 6.6
Referred pain 6.4
PAIN 6.0
feeling tired 5.9
Buckling 5.5
BHS 5.4
abnormal gait 5.2
Joint hypermobility 5.2
joint stiffness 5.1
knee pain 5.0
generalized pain 4.5
loss of balance 4.3
disturbed balance 4.3
spasticity 4.1
distraction 4.0
arthralgia 4.0
elbow pain 3.9
pain 3.8
No adverse effect 3.8
metatarsalgia 3.7
Postoperative pain 3.7
Tenderness 3.6
breakthrough pain 3.4
functional recovery 3.3
heel pain 3.3
Stiffness 3.2
low back pain 3.2
decreased appetite 3.0
incoordination 2.9
Fluctuation 2.9
muscle stiffness 2.9
tingling 2.8
numbness 2.8
hemiplegia 2.8
thinning 2.7
back pain 2.7
collapse 2.7
clonus 2.6
chronic back pain 2.6
sciatica 2.5
acute pain 2.5
torticollis 2.5
rigors 2.5
weakness 2.5
discomfort 2.5
discomfort 2.4
fatigue 2.2
pelvic pain 2.2
analgesia 2.0
overweight 1.9
hypertonia 1.9
Mills 1.8
neck pain 1.8
anesthesia 1.7
hypotonia 1.6
paresthesia 1.5
spasm 1.3
acute abdominal pain 1.2
leg pain 1.2
skin irritation 1.1
masculinization 0.8
paresis 0.6
bone pain 0.5
colic 0.5
myalgia 0.5
acute stress -0.0
dizziness -0.1
shortness of breath -0.2
insomnia -0.2
Ill -0.3
nausea -0.4
seizures -0.4
abdominal pain -0.8
ataxia -0.8
starvation -0.9
hypothermia -0.9
nausea and vomiting -1.1
constipation -1.2
cough -1.4
exhaustion -1.6
chest pain -1.9
tremor -2.0
angina -2.2
dyspnea -2.6
headache -2.6
vomiting -2.8
Drug
THA 8.7
Actonel 8.3
Risedronate sodium 7.4
CLS 7.3
Vitamin-E 6.9
Icodextrin 6.4
Evista 6.1
Pyridostigmine bromide 5.7
Ethibond 5.4
Posture 5.1
Cilazapril 5.0
Ibandronate 4.9
CFX 4.8
BOTOX 4.7
CrCl3 4.6
NOV 4.4
RAL 4.2
Iloprost 4.1
GNA 4.1
Mezlocillin 4.1
Denosumab 4.1
ID2 4.0
Premarin 3.9
Fondaparinux 3.8
Teriparatide 3.7
Dalteparin 3.7
Raloxifene 3.6
Tenofovir 3.5
MDM 3.5
DPA 3.4
CVA 3.3
CSI 3.3
PFT 3.2
EHDP 3.2
MTC 3.2
Glide 2.8
CAM 2.6
Captopril 2.6
PMPA 2.5
Zoledronic acid 2.5
ROC 2.4
DBS 2.4
DEX 2.3
Parkin 2.3
Parkin 2.3
Frontal 2.1
Luteinizing 2.1
Spectrum 2.0
Infliximab 2.0
Infliximab 2.0
AMC 1.9
CoCl2 1.9
CoCl2 1.9
Methylene blue 1.8
ZnCl2 1.8
ZnCl2 1.8
CTX 1.7
CTX 1.7
Growth hormone 1.6
Growth hormone 1.6
Triclosan 1.5
Ranitidine 1.5
PTH 1.4
Kenyan 1.4
vitamin E 1.4
DMI 1.1
MDS 1.0
G418 1.0
Fragment 1.0
CDP 1.0
TAT 0.9
Albumin 0.9
Angiotensin II 0.8
CTX 0.8
Fraction 0.8
Nitric Oxide 0.8
Alanine 0.7
Ringer's solution 0.7
MOF 0.6
ADM 0.5
Vitamin E 0.5
MRC 0.4
niacin 0.3
ICI -0.2
caffeine -0.2
Indomethacin -0.5
CaCl2 -0.5
CaCl2 -0.5
lysine -0.5
CaCl2 -0.5
Leaf -0.7
EE2 -0.8
Monit -0.9
Dial -1.2
CSF -1.2
TiO2 -1.3
ascorbate -1.3
Asn -1.4
lactose -1.9
ampicillin -1.9
Asthma -2.5
Cardiovasc -2.6
Dermatol -4.9
Enzyme
thiosulfate dehydrogenase 7.4
heterodisulfide reductase 5.6
MCS 5.1
CDH 5.0
thrombin-activatable fibrinolysis inhibitor 4.2
LIS 3.9
calpain 3 3.4
CPN 3.4
MDP 3.3
TGT 3.1
firefly luciferase 3.0
ACE 2.9
CPS 2.8
CPT 2.8
CPT 2.7
proteasome 2.7
insulin-degrading enzyme 2.6
FAST 2.6
SST 2.6
TMT 2.5
CAD 2.4
CAD 2.4
acylase 2.3
CAD 2.3
CPT 2.3
MEKK1 2.3
interstitial collagenase 2.3
chaperonin 2.1
granzyme B 2.0
TPP 1.8
PGM 1.7
indoleamine 2,3-dioxygenase 1.7
TPP 1.6
alpha-mannosidase 1.6
cathepsin K 1.3
MPP 1.3
botulinum neurotoxin 1.3
glucoamylase 1.1
lactase 1.1
matrix metalloproteinase 9 1.0
TAT 0.9
CD10 0.5
ATPase 0.5
GSK 0.4
caspase-8 0.4
S1 nuclease 0.3
enolase 0.3
NO synthase 0.2
thromboplastin 0.0
malate dehydrogenase -0.0
IKK -0.1
kinesin -0.1
glutamine synthetase -0.2
renin -0.2
pyruvate kinase -0.2
alkaline phosphatase -0.2
urokinase-type plasminogen activator -0.2
luciferase -0.3
tissue plasminogen activator -0.3
phosphoinositide 3-kinase -0.4
NQO1 -0.4
CYP3A4 -0.5
aldehyde dehydrogenase -0.5
thrombin -0.6
protein kinase -0.6
glutathione S-transferase -0.7
APC -0.8
succinate dehydrogenase -0.8
xanthine oxidase -0.9
guanylate cyclase -0.9
pepsin -0.9
complex I -1.0
gamma-glutamyl transpeptidase -1.0
creatine kinase -1.1
transcriptase -1.1
mitogen-activated protein kinase -1.2
focal adhesion kinase -1.3
caspase-3 -1.4
AMP-activated protein kinase -1.5
ERK -1.6
neuraminidase -1.7
beta-galactosidase -1.7
peroxidase -1.8
calcineurin -1.9
MEK -2.0
collagenase -2.0
endonuclease -2.0
trypsin -2.2
protein kinase C -2.4
alanine aminotransferase -2.6
lactate dehydrogenase -2.7
reverse transcriptase -2.8
RNA polymerase -2.9
ACS -3.1
Compound
His-Leu 9.2
Enduron 8.2
CHIP 7.7
CI 100 7.6
5-phosphomevalonate 7.5
5-aminoisophthalic acid 7.5
CLS 7.4
Decoquinate 7.3
Thiothixene 7.3
BTO 7.3
Cyclobenzaprine 7.2
5-hydroxyisophthalic acid 7.1
5-hydroxyisophthalic acid 7.1
Xanthurenic acid 6.6
BMD 6.2
Flucloxacillin 6.2
Mepivacaine 6.0
Prone 5.5
Zirconia 5.5
B 5 5.4
AFC 5.4
EOS 5.3
Ropivacaine 5.2
Taxifolin 5.1
Alendronate 5.1
Angiotensin I 5.1
Alendronate 5.0
Dolichol 4.9
CDH 4.8
PIH 4.8
[1,10]phenanthroline 4.8
isophthalic acid 4.7
Risedronate 4.7
Cobalt 4.6
Tranexamic acid 4.3
Triamcinolone acetonide 4.3
Triamcinolone 4.3
BAS 4.2
NFA 4.2
sulfamic acid 4.2
Geldanamycin 4.2
[1,10]phenanthroline 4.1
MHS 4.0
Cyanogen bromide 4.0
chromium 4.0
PCMB 4.0
PCMB 4.0
PCMB 4.0
HMS 4.0
PCMB 3.9
TEP 3.9
Premarin 3.8
Raloxifene 3.8
cobalt 3.8
DPA 3.6
DPA 3.6
Safranin O 3.6
DLT 3.6
titanium 3.6
ASA 3.6
Austin 3.5
DPA 3.5
DPA 3.4
TGT 3.4
NH4OH 3.4
EHDP 3.4
DPA 3.4
Morin 3.4
Enalapril 3.4
DPA 3.3
3-hydroxyanthranilic acid 3.3
Hydroxychloroquine 3.3
PDP 3.2
DPA 3.2
AGE 3.2
DPA 3.2
DPA 3.2
DPA 3.2
DPA 3.2
THE 3.2
DPA 3.2
MTC 3.1
DHA 3.1
B17 3.1
vitamin D 3.1
Tobramycin 3.0
LPR 3.0
Thiobarbituric acid 3.0
T10 2.9
Safranin O 2.9
Match 2.9
keratan sulfate 2.9
CPT 2.8
BHA 2.8
HBA 2.8
CPT 2.7
2,6-diisopropylphenyl 2.7
HAP 2.7
oxalacetate 2.6
DEA 2.5
DEA 2.5
5-HTP 2.5
DEA 2.5
Vitamin D 2.5
Chondroitin sulfate 2.4
HMM 2.4
5-HTP 2.4
NiCl2 2.4
Polypeptide 2.4
Premarin 2.4
Tumor Necrosis Factor 2.4
Warfarin 2.4
DBS 2.4
A 1 2.3
Octreotide 2.2
Hypo 2.2
T 1 2.2
threonine 2.1
Wellcome 2.1
strontium 2.1
hyaluronic acid 2.0
Valproic acid 2.0
Coronal 2.0
Belt 1.9
L-leucine 1.9
Vancomycin 1.9
DCP 1.9
A 3 1.8
Statin 1.8
CAM 1.8
Pro-Gly 1.7
TPP 1.7
dihydrogen phosphate 1.7
PMSF 1.7
dihydrogen phosphate 1.7
Uric acid 1.7
HPP 1.7
Estrogen 1.6
Angiotensin II 1.6
Benin 1.6
PIN 1.6
Ara-C 1.5
DMS 1.5
8-OHdG 1.5
Methamphetamine 1.4
MPP 1.4
TPP 1.4
MPP 1.4
1H-imidazole 1.3
6-12 1.3
Cbl 1.3
TCP 1.3
TCP 1.3
BNP 1.3
ANCA 1.3
DCP 1.3
Pyruvate 1.3
D-Ala 1.3
Gentamicin 1.3
Methylene blue 1.3
more...