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Query: UNIPROT:P50502 (Hip)
 7,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hydroxyapatite (HA)-coated APR Total Hip Replacement was found to be superior to a press-fit only control group in a randomized trial. This study confirms the importance of biologic fixation for durability of total hip replacement as compared with press-fit fixation only.
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PMID:Clinical results from the calcitite-coated press fit APR hip system. 131 Jun 56

The APR-I Hip System was designed for metaphyseal bone attachment by proximal patch porous coating and the acetabular component was a hemisphere fixed with screws. The results of 100 consecutive primary total hip arthroplasties performed with the APR-I were studied in patients still alive after an average of 6.7 years. The selection of hips for implantation of this hip system was limited to those patients in whom a satisfactory intraoperative fit could be obtained. This resulted in a distribution of patients such that 75% were younger than age 65 years and only 15% had osteoporotic bone. The revision rate was 16% with a mechanical failure rate of 11%. Seventy percent of hips had progressive loss of fixation. loss of femoral component fixation was correlated with younger patient age, higher patient activity level, metaphyseal fill of less than 90%, and increased polyethylene wear and osteolysis. Eighty-nine percent of hips maintained femoral neck contact with the porous coated collar. The acetabular component was well fixed in 97% of hips. The failure rate of the APR-I stem is unacceptably high and this stem is no longer used by the authors.
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PMID:Failure mechanisms of anatomic porous replacement I cementless total hip replacement. 900 9