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Query: UNIPROT:P50502 (Hip)
 7,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We investigated the radiological and epidemiological data of 4,151 subjects followed up from 1976 to 2003 to determine individual risk factors for hip osteoarthritis (OA), hip pain and/or treatment by total hip replacement (THR). Pelvic radiographs recorded in 1992 were assessed for evidence of hip-joint degeneration and dysplasia. Sequential body mass index (BMI) measurements from 1976 to 1992, age, exposure to daily lifting and hip dysplasia were entered into logistic regression analyses. The prevalence of hip dysplasia ranged from 5.4% to 12.8% depending on the radiographical index used. Radiological hip OA prevalence was 1.0--2.5% in subjects <60 years of age and 4.4--5.3% in subjects >or=60 years of age. While radiological OA was significantly influenced by hip dysplasia in men and hip dysplasia and age in women, the risk of THR being performed was only influenced by BMI assessed in 1976. Hip-joint degeneration and treatment by THR do not necessarily share the same risk factors, and caution should be exercised in epidemiological studies in attributing one or the other as the end point of coxarthrosis.
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PMID:Increased body mass index is a predisposition for treatment by total hip replacement. 1585 29

Running has steadily gained in worldwide popularity and is the primary exercise modality for many individuals of all ages. Its low cost, versatility, convenience and related health benefits appeal to men and women of broad cultural, ethnic and economic backgrounds. With more children and adults participating in recreational and competitive running, the incidence of injuries has steadily increased. Most running-related injuries affecting the lower extremities are due to preventable training errors, and some may necessitate medical evaluation or a significant reduction in training. Hip injuries in runners are due to interactions of intrinsic and extrinsic factors that adversely affect the complex regional anatomy. Acute or chronic hip pain presents a diagnostic and therapeutic challenge because the vague, nonspecific symptoms and signs may originate from local, regional or distant foci. Muscle strains and tendonitis are the most common aetiologies of hip pain and typically result from sudden acceleration/deceleration manoeuvres, direction changes or eccentric contractions. Apophysitis and avulsion fractures may affect younger runners and produce localised pain at muscle attachment sites. Iliotibial band syndrome is a common cause of lateral hip and knee symptoms characterised by sharp or burning pain that is exacerbated by activity. Bursitis, due to repetitive activity or acute trauma, may affect the trochanteric, ischial or iliopectineal bursae. Hip osteoarthritis may also produce persistent pain that worsens with running. Stress fractures are potentially serious conditions that affect women more frequently than men. Snapping hip syndrome is a benign condition that results from tight connective tissues' passing repeatedly over the greater trochanter, anterior hip capsule, lesser trochanter, femoral head or iliopectineal eminence. Acetabular labral tears, sports hernias and nerve entrapment syndromes are also potential causes of persistent hip pain in runners. Treatment of hip pain in running should focus not only on addressing the symptoms but also identifying the underlying conditions that precipitated the injury. Injury prevention and comprehensive rehabilitation are essential, since prior hip injuries increase the risk of subsequent ones. Coaches, trainers and medical personal who care for runners should advocate running regimens, surfaces, shoes, technique and individualised conditioning programmes that minimise the risk of initial or recurrent hip injuries.
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PMID:An overview of hip injuries in running. 1627 Oct 11

Quality of life outcome and patient satisfaction after total hip arthroplasty are complex phenomena and many confounding determinants have been identified. Degenerative disease of the hip joint may present with variable patterns of pain referral in the lower limb. However the effect of varied preoperative pain referral patterns on patient outcome and satisfaction after total hip arthroplasty has not previously been examined. From 2000 to 2003, 236 eligible patients scheduled to undergo primary total hip arthroplasty were prospectively enrolled. The principal pain referral pattern (as hip, thigh or knee) was identified in all patients. Health related quality of life (HRQOL) was examined using the Harris Hip score (HHS), the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) and the 36-Item Short-Form Health Survey (SF-36) pre-operatively, 1 year and 2 years postoperatively and with the HHS at 3 months postoperatively. All patients were followed up for a minimum of 2 years. The frequency of the pain referral distributions were; hip pain 41%, knee pain 32% and thigh pain 27%. Patients in all groups were comparable preoperatively with respect to age, HHS, and both mean and domain specific WOMAC and SF-36 scores. The mean duration of symptoms was significantly greater in patients with knee pain when compared to the remaining two pain patterns. All patients demonstrated improvements in HHS, SF-36 and WOMAC scores after surgery. At all times postoperatively there were significant differences in mean HHS and mean and domain specific WOMAC and SF-36 scores between patients with hip or thigh pain and those with knee pain (p < 0.001). While notable, differences between hip and thigh pain were not as consistent however. Based on these findings, it appears that pre-operative pain referral patterns of hip arthritis are among the determinant factors for patient outcome and satisfaction after total hip arthroplasty, as measured using validated HRQOL scoring systems.
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PMID:Do pain referral patterns determine patient outcome after total hip arthroplasty? 1630 78

New research has changed our perception and management of common injuries. Magnetic resonance imaging and arthroscopy of the hip have shown that labral injuries, chondral injuries, rim lesions, synovitis and tears of the ligament teres are common causes of hip, groin and low-back pain. Hip arthroscopy is used both as a diagnostic and therapeutic tool; it has been shown to be of benefit in recent traumatic labral injury, but disappointing in the management of chronic hip pain (which may be associated with degenerative change, and chondral lesions of the acetabulum). The McConnell multimodal physiotherapy regimen is effective in treating patellofemoral pain. Anterior cruciate ligament rupture is three to five times more common in women, but neuromuscular training appears to decrease its incidence. Patellar tendon and hamstring grafts appear to be equally effective in anterior cruciate ligament reconstruction. Articular cartilage defects remain a significant problem, and the efficacy of treatments such as autologous chondrocyte implantation is still unclear.
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PMID:5. Recent advances in sports medicine. 1648 7

Hip arthroscopy is a procedure that is gaining popularity for treating hip pain related to intraarticular cartilage lesions or loose bodies. It offers an alternative procedure that can decrease or eliminate hip pain and increase a patient's ability to do activities of daily living. This article provides a comprehensive overview of hip arthroscopy and also addresses the anatomy of the hip, appropriate diagnoses for the procedure, operative considerations and postoperative teaching.
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PMID:Arthroscopy of the hip joint: an overview. 1657 24

Hip impingement is now recognized as a relatively common cause for hip pain in young adults. The early evolution of impingement begins in childhood in several common hip disorders (slipped capital femoral epiphysis, Perthes, early avascular necrosis due to other causes). Recognition and treatment of childhood impingement may prevent the evolution to early hip arthritis.
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PMID:Impingement and childhood hip disease. 1675 30

In the 20-50-year age group, hip pain usually indicates dysplasia. Chronic mechanical pain is the usual pattern, although acute pain caused by avulsion or degeneration of the labrum may occur. The morphological characteristics of the dysplastic hip should be evaluated, and the link between the dysplasia and the osteoarthritis should be confirmed. Three factors indicate a favorable prognosis: joint space preservation, age younger than 40 years, and correctable femoral and acetabular abnormalities. Reconstruction is highly desirable, as it delays the need for joint replacement by 20 years. After 15 years, good outcomes are seen in 87% of patients after shelf arthroplasty and 85% after femoral varus osteotomy with or without shelf arthroplasty. Chiari acetabular osteotomy can be performed in patients with osteoarthritis but is followed by prolonged limping. Periacetabular osteotomy should be reserved for patients with moderate dysplasia and no evidence of osteoarthritis. Shelf arthroplasty and femoral osteotomy require 5-8 months off work (compared to 5 months after hip replacement surgery) but subsequently permits a far more active lifestyle. Hip replacement, which is required 20 years or more after biologic reconstruction, carries the same prognosis as first-line hip replacement (good results in 80% of patients after 15 years). Acute sharp pain related to anterior hip derangement also occurs in primary femoroacetabular impingement (FAI). The most common pattern is cam impingement, which is due to a decrease in head-neck offset and manifests as pain during flexion and adduction of the hip. Cam impingement can be corrected by anterolateral osteoplasty, which is often performed arthroscopically. Pincer-type impingement is contact between the anterior acetabular rim and the femoral neck due to retroversion of the proximal acetabulum. The imaging study strategy is discussed. Coxometry, computed tomography, and arthrography can be used. Primary FAI, which occurs as a result of geometric abnormalities, should be distinguished from secondary impingement. Causes of secondary impingement include exaggerated lumbar lordosis with pelvic tilt and to hip osteophytosis (sports or posterior hip osteoarthritis). Osteoplasty is rarely appropriate in patients with secondary impingement. The features of acute anterior hip derangement are now better defined. They can be used to guide palliative treatment, which is effective, in the medium term at least. Experience acquired over the last two decades has established the efficacy of surgery for hip dysplasia.
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PMID:Hip pain from impingement and dysplasia in patients aged 20-50 years. Workup and role for reconstruction. 1713 20

A survey was distributed to the American Association of Hip and Knee Surgeons (AAHKS) membership to evaluate surgical treatment preferences for displaced femoral neck fractures (DFNFXs). Of 718 members, 381 (54%) responded to the 16-question survey that was an adjunct to a multicenter, randomized study (funded by AAHKS/OREF) designed to prospectively evaluate efficacy of hemiarthroplasty vs total hip for treatment of DFNFXs. Hemiarthroplasty (85%) was the most preferred treatment option for DFNFXs (reduction with internal fixation 2%, total hip arthroplasty 13%). Prefracture hip pain/osteoarthritis, poor bone quality, and fracture comminution were the main reasons why arthroplasty was chosen over reduction with internal fixation. Ambulatory status and dislocation risk after arthroplasty were the main factors in choosing between unipolar (48%) and bipolar (52%) hemiarthroplasty. Total hip arthroplasty is used by 88% of responders. Dislocation risk and ambulatory status were influential factors against performing total hip arthroplasty. Arthroplasty is the preferred method of surgical intervention for the treatment of DFNFXs for AAHKS members.
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PMID:Surgical treatment of displaced femoral neck fractures in the elderly: a survey of the American Association of Hip and Knee Surgeons. 1716 71

Osteoarthritis (OA) presupposes the interaction of systemic and/or local factors. In hip joint OA, congenital or developmental malformation is believed to constitute an individual risk factor for premature degeneration. Hip dysplasia (HD) is such a malformation. The radiological and epidemiological studies had several aims: To critically evaluate the radiological source material of the Copenhagen Heart Study: The Osteoarthritis Substudy, consisting of 4,151 standardized, weight bearing pelvic radiographs recorded 1991-1994. To qualify or disqualify the radiological source material for further studies. To develop a comprehensible and reproducible radiographic discriminator of hip OA with as close an association to self reported hip pain as possible. To identify prevalences of hip OA and HD in a Caucasian, urban background population and investigate the influence of sex, age, physical and occupational parameters on these prevalences. To evaluate the influence of HD on hip OA development relative to other potential risk factors. To evaluate degeneration in dysplastic hips over time. To evaluate the three dimensional anatomy of HD and the distribution of degenerative features in severely dysplastic hips, and To evaluate risk factors for total hip replacement surgery. In the course of the studies we found that assessments of classic indices of HD were significantly influenced by pelvic orientation during x-ray recording and identified exclusion limits of rotation and inclination/reclination of pelvic radiographs to stay inside a measurement error of +/- 3 degrees. We found that minimum joint space width (JSW) </= 2.mm constituted a radiologic hip OA discriminator of superior reproducibility and clinical relevance compared to composite, radiological OA classifications. We documented a progressive postmenopausal decline in female minimum JSW, while male minimum JSW remained relatively unaltered throughout life. We found no evidence that smoking, occupational exposure to repeated, heavy lifting or overweight significantly influenced minimum JSW. Prevalences of hip OA was approximately 5.5% in subjects >/= 60 years of age, and HD prevalence was 4-10%, depending on the radiographic criteria applied. Age and HD were significant risk factors for hip OA development in women, and HD was found to be a significant risk factor for hip OA in men. However, only obesity was found to determine an event of hip replacement surgery. In a longitudinal study of 81 subjects and with mild or moderate hip dysplasia followed for a decade we did not document a tendency for radiological degeneration compared to 136 control subjects. In a computerized tomographic study of severely dysplastic hips we found a close relationship between insufficient anterior, acetabular containment and proximal femoral anteversion. The primary area of degeneration in dysplastic hips was in the antero-lateral quadrant of the joint.
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PMID:Adult hip dysplasia and osteoarthritis. Studies in radiology and clinical epidemiology. 1738 May 95

Femoroacetabular impingement (FAI) occurs when an osseous abnormality of the proximal femur (cam) or acetabulum (pincer) triggers damage to the acetabular labrum and articular cartilage in the hip. Although the precise etiology of FAI is not well understood, both types of FAI are common in athletes presenting with hip pain, loss of range-of-motion, and disability in athletics. An open surgical approach to decompressing FAI has shown good clinical outcomes; however, this highly invasive approach inherently may delay or preclude a high level athlete's return to play. The purpose of this study was to define associated pathologies and determine if an arthroscopic approach to treating FAI can allow professional athletes to return to high-level sport. Hip arthroscopy for the treatment of FAI allows professional athletes to return to professional sport. Between October 2000 and September 2005, 45 professional athletes underwent hip arthroscopy for the decompression of FAI. Operative and return-to-play data were obtained from patient records. Average time to follow-up was 1.6 years (range: 6 months to 5.5 years). Forty two (93%) athletes returned to professional competition following arthroscopic decompression of FAI. Three athletes did not return to play; however, all had diffuse osteoarthritis at the time of arthroscopy. Thirty-five athletes (78%) remain active in professional sport at an average follow-up of 1.6 years. Arthroscopic treatment of FAI allows professional athletes to return to professional sport.
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PMID:Femoroacetabular impingement in 45 professional athletes: associated pathologies and return to sport following arthroscopic decompression. 1747 50


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