Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50502 (Hip)
 7,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hip fracture incidence accelerates approximately 10 years following the menopause in women and after age 70 in men. Approximately one million Americans suffer fragility fractures each year at a cost of over 14 billion dollars. The disability, mortality and cost of hip and vertebral fractures are substantial in the rapidly growing aging population so that prevention of osteoporosis is a major public health concern. Bone mineral density (BMD) measurement is used to make the diagnosis of osteoporosis prior to incident fracture, and to predict fracture risk. Recommendations for treatment and prevention of osteoporosis based on bone mineral density score published by the World Health Organization and the National Osteoporosis Foundation are outlined.
Conn Med 2003 Sep
PMID:Osteoporosis in older men and women. 1458 28

Falls are the most common cause of trauma in the elderly. Data regarding patterns of injury following geriatric falls are scant. We conducted a retrospective review of falls in patients aged 65 years and older seen at a trauma center over a nine year period. Two thousand eighty three patients met the inclusion criteria. Hip fracture proved to be the dominant injury (55%), 98% of which were isolated. Five hundred seven (21%) were non-hip fractures. Two hundred thirty eight patients (10%) sustained traumatic intracranial hemorrhage. Chest injury was the next most common injury type (6.7%) with rib fractures comprising 86% of this subgroup. A pattern of association between intracranial hemorrhage and cervical spine fractures was identified. Intra-abdominal injuries are rare.
Conn Med 2009 Mar
PMID:Patterns of injury in geriatric falls. 1935 88

Total joint replacement and tibial osteotomies have been used for decades to return the individual to activities and relieve pain. According to the American Academy of Orthopaedic Surgeons, joint replacement is considered one of the most successful medical innovations of the 20th century. Hip and knee-replacement operations are increasing in frequency and are continuing to achieve pain relief and improve function for patients with arthritic joints. Demand for knee replacement is expected to double over the next five to 10 years and for hip replacement, it is expected to double over the next 10 to 15 years. The trend for joint replacement has begun to include the younger as well as the older still active individual. Younger patients are considering joint-replacement surgery earlier in life due to advances in surgery and devices. Since children begin sports at a fairly early age, once they reach young adulthood, their joints have sustained recurrent internal impact for many years leading to degeneration earlier in life. These younger patients are expecting and choosing to participate in sports even after surgery. They want to be able to coach and play sports with their children without pain. While pain relief has historically been the main reason people have joint replacement surgery--the need to improve joint-function has also become motivating for patients--especially those involved in athletic activities. Patients and orthopedic surgeons do not necessarily worry about the same things after joint-replacement surgery.
Conn Med 2012 Sep
PMID:Returning to sports after total joint replacements and tibial osteotomies: is it possible? 2306 Dec 14