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Query: UNIPROT:P50502 (Hip)
 7,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The design of and early clinical results with the uncemented porous-coated LSF Anatomic and Midstem Total Hip Systems are described. In a Food and Drug Administration-approved program, a random selection method was used to determine which patients receive implants with a hydroxyapatite (HA) coating applied to the porous surface and which patients receive non-HA-coated implants. The early clinical results with the HA-coated systems appear superior to the non-HA-coated systems. A greater percentage of patients with HA systems have clinical scores in the excellent/good range, which is primarily a reflection of less prosthesis-related pain. Radiographically, all components appear well fixed with evidence of bone ingrowth. The HA-coated systems have a decreased incidence of radiolucencies, particularly in proximal zones.
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PMID:Early clinical results with the hydroxyapatite-coated porous LSF Total Hip System. 131 Jun 57

Forty-nine consecutive uncemented porous-coated LSF total hip prostheses were implanted in 41 patients and studied prospectively. Clinical rating as described by Harris was performed preoperatively, at 6 months and 1 year postoperatively, and annually thereafter. Anteroposterior and lateral radiographs were obtained preoperatively, immediately postoperatively, at 6 and 12 months, and annually thereafter. At the most recent follow-up visit, patients were evaluated clinically and radiographically utilizing the format recently recommended by the Hip Society. A patient satisfaction questionnaire was also completed. The follow-up period averaged 37 months (range, 24-48 months). Preoperative hip scores averaged 38 (range, 18-68) and improved to 93 at the most recent follow-up visit (range, 76-100). The incidence of mild pain was 14% at 1 year and 4% at 2 years or more. The incidence of limp was 16% slight and 8% moderate at 1 year, and 12% slight and 2% moderate at 2 years or more. Surgical fit was objectively graded as excellent in 61%, good in 33%, and poor in 6%. The authors were unable to correlate surgical fit with clinical scores or radiographic findings. According to radiographic criteria, all components were judged to be stable and 86% were judged to demonstrate objective signs of osseointegration. Patient satisfaction with the procedure was 100%. All patients stated that the procedure increased their function and decreased their pain and need for medication. Compared to a normal hip, in terms of symptoms and function, the patients rated their postoperative hip at 85% (range, 50-100%). Compared to their level of activity before their hip was symptomatic, they rated their current activity level as 83% (range, 50-100%).
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PMID:Clinical and radiographic analysis of the uncemented LSF total hip arthroplasty. 143 16